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Difference between revisions of "Talk:MitoEAGLE protocols, terminology, documentation"

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== Participants ==
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== Comments and discussion ==
::::# '' We are mostly interested in two WG: (1) Since we are working mostly  with heart and muscles, we are interested in WG 2 - MITOEAGLE data  repository in muscle and other tissues. (2) WG 1 - Standard operating  procedures and user requirement document: Protocols, terminology,  documentation. Since we have an expertise in fatty acid metabolism, we  are specially interested in experimental protocols for the evaluation of  mitochondrial capacities regarding fatty acid metabolism. Of course our  parts of the WG are also in our interest.'' - '''[[Makrecka-Kuka M| Marina Makrecka-Kuka]], [[Liepinsh E|Edgars Liepinsh]]''' (2016).
::::# '' My role in Mito-EAGLE would be mainly in WG 2 and 4, with a focus on  skeletal and cardiac muscle and cultured cardiomyocytes and endothelial  cells. I would particularly like to bridge the gap between the group  leaders and young investigators, trying to represent the young people  who are the active users of the OROBOROS equipment. This will fit in  nicely with the goals in WG1. ... Major congratulations on obtaining  this beautiful collaborative grant! Very glad to see this network  getting the recognition it deserves! Looking forward to being part of  this!'' - '''[[Wuest RC| Rob C Wuest]]''' (2016).
::::# ''Please, find enclosed my declaration to participate with my team in the following workgroups: WG1, WG2, WG3, WG4. We are now involved and have been in not a distant past – in studying of the following cell /tissue types: 
::::## ''Blood cells, with particular emphasis on platelets and lymphocytes – isolated from animals and humans.
::::## ''Endothelial cells, fibroblasts, neurocytes (neuroblastoma), astrocytes, cancer cell lines – predominantly cultured.
::::## ''Hepatocytes, cardiomyocytes, cell isolated from brain – isolated from lab animals. - '''[[Watala C| Cezary Watala]]''' (2016).
::::# ''I have already contacted the portuguese CNC to nominate me for  the MC of theaction. Concerning my active participation, taking into  account the type of work we do in my lab I could be included in all WGs.  As you know we work with mitochondria from liver, muscle and fat, as  well as cultured cells from different origins (WG2-4). The elaboration  of SOPs (WG1) we can certainly contribute (see the book I edited on  Mitochondrial Bioenergetics and in which you contribute a chapter). I  believe that everybody can be part of the WG5, but as the coordinators  of the action, you and Sandra should decide what is best for the success  of the action.'' - '''[[Palmeira C |Carlos Palmeira]]''' (2016).
::::# ''I would propose my participation in the WG1: Standard operating procedures and user requirement document: Protocols, terminology, documentation, considering that the goal of WG1 is to establish an integrated and analytic environment linking mitochondrial respiration with external data (cell physiology, anthropometry, spiroergometry, lifestyle, genomics) in the context of physical fitness evaluation and clinical diagnostics. I could give my active contribution in the phase of making platform that will aggregate the Action’s complete knowledge and provides the ability to make diagnostic profiling associated with diseases in particular tasks:
::::## ''Develop reccomendations for quality control, data reporting and data sharing beyond the published record. Develop concepts on Open Access and institutionalised service for data management, data mining and health-care conforming standards of data interpretation 
::::## ''Provide a summary on strategic dissemination and an education programme for MITOEAGLE.
::::## ''Considering that we are in process of buying the oxygraph, thus broading capacities of my lab, I would be happy to open the door of my new lab for the innovative inter-laboratory  ring test experiments and together with my team contribute in that phase of the MITOEAGLE Action. I look forward to the establishment of MitoGlobal EAGLE network where, as stated in the MoU,  researchers will collaborate on mapping mitochondrial physiology and medicine. The creation of such a unique well-coordinated network of senior researchers and young investigators will definitely put an added value to existing data and publications, will increase quality and validity of the research, will bring new possibilities of data sharing and data mining  and will hopefully bring us to the era of more economical research by saving resources through standardised and harmnonised protocols, where the measuremnts will not be wasted due to lack of comparability.'' - '''[[Lalic Nebojsa|Nebojsa Lalic]]''' (2016).
::::# ''Our research interest is oriented to reproductive endocrinology; especially to mechanisms that govern steroidogenesis of testicular Leydig cells in disturbed homeostasis. We use several in vivo models:'' 
::::## ''stress -/+ systemic or intratesticular blockade of different stress receptors (alpha1ADR; betaADR; GR)
::::## ''hypogonadal-hypogonadism -/+ testosterone-replacement therapy 
::::## ''androgens anabolics treatment -/+ blockade od AR
::::## ''aged rats -/+ Viagra-treatment 
::::## ''biological clock'' - '''[[Andric S|Silvana Andric]]''' (2016).
::::# ''I took a look to the MoU and the different working groups. You know well my research focus and having this into account I am interested in actions related to Working group 1 (Respirometric reference protocols, Interlaboratory proficiency test, Instrumental platforms). Working group 2 and 3: I have generated multiple mitochondrial respiration data sets in different mouse tissues (mainly in skeletal muscle, hypothalamus, liver and white adipose tissue). Currently we are also performing these assays in white adipose tissue from human patients. Hence I am interested in all milestones of WG 2 and 3. WG 5 is related to WG 1 and as you know I have interest in training, dissemination and also together with my collaborators (if needed) we could help with data sets and a data interpretation.  Overall, I have a general interest on this Action and my active role in MITOEAGLE could be discussed. I could be of help participating in some of the tasks where my expertise and interest fit best. We will be forming and interdisciplinary research group with four group leaders: JC Perales, R Guimera, M Sales-Pardo and PM Garcia-Roves with two different affiliations, University of Barcelona (JCP and PMG-R - Energy metabolism) and University Rovira I Virgili (RG and MS – Data base, statistics, data mining).'' - '''[[Garcia-Roves PM|Pablo M Garcia-Roves]]''' (2016).
::::# ''I will be pleased to contribute to the tasks of WG1 by developing interlaboratory proficiency tests and instrumental platform comparison. Moreover, as a (potential) MC member of MitoEAGLE I can also  offer visibility to the Action itself (i.e. WG5: MITOEAGLE dissemination  and training, according to mitoglobal.org webpages)  by establishing  new interactions with the International Coenzyme Q10 Association (ICQA)  where I act as a member of the Executive Committee. ICQA organizes  biennal conferences on  new highlights of Coenzyme Q research. In 2015,  we held the conference in Bologna  (http://conference2015.wix.com/icqaconference) and we included in the  program also some scientific sessions dedicated to mitochondrial  bioenergetics and diseases. I will be pleased to enforce cooperation  between ICQA and MitoEAGLE.'' - '''[[Genova ML| Maria Luisa Genova]]''' (2016).
::::# ''We found the scientific content and objectives of the call very  interesting and compatible with our wide expertise on oxysterol analysis  in food and biological systems. Our group has a large experience on  lipid composition and their degradation products (volatile and  non-volatile), as well as on sensory analysis.    Moreover, we are currently involved in the H2020-GERI-2014-1 project  "PLOTINA" ("Promoting gender balance and inclusion in research,  innovation    and training") with Prof. Gallina Toschi (in cc) as coordinator; the  project actually includes gendered case studies where gender and sex  variables are    considered. You can find further information about our expertises, publications and  the PLOTINA project at the following webpages: https://www.unibo.it/sitoweb/maria.rodriguez/, https://www.unibo.it/sitoweb/tullia.gallinatoschi/, http://www.unibo.it/en/research/projects-and-initiatives/research-projects-horizon-2020-1/plotina'' - '''[[Rodriguez Estrada MT| Maria Teresa Rodriguez Estrada]]''' (2016).
::::# ''As you know, our current/developing interests are with "evolution" (species comparisons) and "environment" (hypoxia and cold exposure), but have also experience and interest in assessing effects of "lifestyle" (diet, exercise) and "aging" as well (in rodents).'' - '''[[Chicco AJ|Adam J Chicco]]''' (2016).
::::# ''Congratulations on the considerable progress with MITOEAGLE! I am keen to participate in this exciting project and I’m sure I can make a valuable contribution to it's success. I have extensive experience performing respirometry assays in human muscle biopsies, myoblasts/tubes and mouse tissues in the contexts of aging, obesity, exercise and inactivity. I feel that I could contribute to any of the five working groups, but particularly to WG2, WG4, and WG5. I am also happy and willing to serve on the Management Committee if needed. Again, congratulations on organizing such an exciting project.'' - '''[[Coen PM|Paul M Coen]]''' (2016).
::::# ''I would be interested to be involved with WG1 and WG2. In particular, I am interested in contributing to developing protocols for multicenter quality control among labs, and for permeabilized muscle bundle respirometry.'' - '''[[Rossiter HB| Harry B Rossiter]]''' (2016).
::::# ''I think that we could contribute via participation in the evaluation of the protocols, and helping to develop them further. In addition, we have been working on the establishing a database that would allow us to keep protocol details, cell isolation and several other aspects. There is nothing very advanced, but we could contribute to establishing such data collection practice. In addition, we, as opposed to many others, happen to use Strathkelvin respirometer. This alternative hardware would allow us to verify whether the protocols work on them as well.'' - '''[[Vendelin M|Marko Vendelin]]''' (2016).
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Participants

CountryCityContact
ArmeniaYerevanTrchounian K
AustraliaMelbourneLionett S
AustraliaClayton VictoriaAlton Lesley
AustraliaNedlandsFilipovska Aleksandra
AustraliaSydneyHoehn Kyle L
AustraliaMelbourneCassar Samantha
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AustraliaQueenslandRadenkovic Filip
AustraliaMelbourneGenders Amanda J
AustraliaSydneyKrycer James R
AustraliaClaytonWolff Jonci Nikolai
AustraliaQueenslandHolland Olivia J
AustraliaNedlandsPerks Kara L
AustraliaMelobourneBotella Javier
AustraliaGeelong, VictoriaMcKenzie Matthew
AustraliaSouthportVidimce Josif
AustraliaMelbourneStepto Nigel K
AustraliaNewtown, SydneyStocker Roland
AustraliaMelbourneWhitfield Jamie
AustraliaVictoriaWinwood-Smith Hugh
AustraliaBurwoodTrewin Adam J
AustraliaQueenslandDong Lan-Feng
AustraliaParkvilleHardee Justin P
AustraliaVictoriaVan Bergen Nicole J
AustraliaMelbourne, VICMuccini Anna Maria
AustraliaMelbourneFerri Alessandra
AustraliaMelbourneSaner Nicholas
AustraliaSyndeyTon Riccardo
AustraliaMelbourneKuang Jujiao
AustraliaQueenslandFisher Joshua J
AustraliaMelbourneHewakapuge Sudinna
AustriaInnsbruckSchmitt Sabine
AustriaInnsbruckThapa Maheshwor
AustriaInnsbruckPlangger Mario
AustriaInnsbruckHoppel Florian
AustriaInnsbruckCecatto Cristiane
AustriaInnsbruckDoerrier Carolina
AustriaInnsbruckSchartner Melanie
AustriaInnsbruckDi Marcello Marco
AustriaInnsbruckBergmeister Lisa
AustriaInnsbruckSobotka Ondrej
AustriaInnsbruckGarcia-Souza Luiz F
AustriaInnsbruckPerez Valencia Juan Alberto
AustriaInnsbruckMeszaros Andras T
AustriaInnsbruckGallee Leon
AustriaInnsbruckSchwarzer Christoph
AustriaInnsbruckLaner Verena
AustriaAldransHaider Markus
AustriaInnsbruckGnaiger Erich
AustriaSalzburgKofler B
AustriaKlosterneuburgSazanov Leonid A
AustriaInnsbruckAntunes Diana
AustriaInnsbruckPassrugger Manuela
AustriaKapferer Werner
AustriaInnsbruckGoebel G
AustriaInnsbruckCardoso Luiza HD
AustriaViennaKozlov Andrey V
AustriaInnsbruckKlocker Helmut
AustriaInnsbruckNindl Veronika
AustriaInnsbruckKarabatsiakis Alexander
AustriaInnsbruckKeller Markus A
AustriaInnsbruckBurtscher Martin
BelgiumNamurArnould Thierry
BelgiumLiegeVotion Dominique-Marie
BelgiumLeuven, FlandersBaekelandt V
BelgiumBrusselsSonveaux P
BelguimSart Tilman (LiĂšge)Kruse C
BrasilPorto AlegreHaas Clarissa
BrasiliaLimeiraRopelle Eduardo R
BrazilSĂŁo PauloKowaltowski Alicia J
BrazilSao PauloSilber Ariel Mariano
BrazilRio de JaneiroGalina Antonio
BrazilJaboticabalOliveira Marcos Tulio
BrazilSĂŁo PauloCrispim Marcell
BrazilRio de JaneiroOliveira Marcus F
BrazilRio de JaneiroVieyra Adalberto
BrazilSao PauloVercesi Anibal E
BrazilSanta Maria - RSGoncalves Debora Farina
BrazilSanta Maria - Rio Grande do SulSoares Felix Alexandre Antunes
CanadaMoncton, NBPichaud Nicolas
CanadaEdmontonHan Woo Hyun
CanadaVancouver, BCTausan Daniel
CanadaQuebecJoseph Vincent
CanadaEdmonton (Alberta)Lemieux Helene
CanadaEdmontonZaugg Michael
CanadaRimouskiMunro Daniel
CanadaMontréalBreton Sophie
CanadaEdmontonLucchinetti Eliana
CanadaHamiltonScott Graham R
CanadaOttawaHarper Mary-Ellen
CanadaMontreal, QuebecBergdahl Andreas
CanadaAntigonishWeir M
CanadaHamiltonTarnopolsky Mark A
CanadaWinnipegChowdhury Subir Roy
CanadaGuelphHolloway Graham P
CanadaVancouverBovard Josh
CanadaSaint JohnPulinilkunnil Thomas
CanadaCharlottetownAdiele Reginald C
CanadaOttawaDarveau Charles-A
CanadaRimouskiBlier Pierre U
ChileCoyhaiqueJana Prado Fabian
ChinaXi`anLiu Jiankang
ChinaFuzhou, Fujian ProvinceChen Qi
ChinaPukou, Nanjing,Gan Zhenji
ChinaTianjinZhang Yong
CroatiaZagrebRubelj Ivica
CroatiaSplitLjubkovic M
CroatiaZagrebSaric A
CroatiaZagrebCurik I
Czech RepublicCeske BudejoviceZikova Alena
Czech RepublicHradec KraloveKucera Otto
Czech RepublicPardubiceHandl Jiri
Czech RepublicPraha 2Danhelovska Tereza
Czech RepublicPlzen -Severni predmestiJedlicka Jan
Czech RepublicVestecEzrova Zuzana
Czech RepublicPardubiceMajtnerova Pavlina
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Czech repHradec KraloveFalaye T
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DenmarkAarhus NJespersen Nichlas Riise
DenmarkRoskildeDalgaard Louise T
DenmarkHvidovreNehlin Jan O
DenmarkCopenhagen NScheibye-Knudsen Morten
DenmarkCopenhagenDela Flemming
DenmarkCopenhagen NMaise Chroeis K
DenmarkCopenhagenNielsen B
DenmarkAarhus NBoetker Hans Erik
DenmarkCopenhagenGonzalez-Franquesa Alba
DenmarkCopenhagenKraunsoee R
DenmarkCopenhagenLarsen Steen
DenmarkCopenhagenSoendergaard SD
EgyptCairoAbdel-Rahman Engy Ali
EgyptCairoAli Sameh S
EstoniaTartuPaju Kalju
EstoniaTallinnPuurand Marju
EstoniaTallinnVendelin Marko
EstoniaTallinnLaasmaa Martin
EstoniaTallinnKaambre Tuuli
EstoniaTallinnTruu Laura
EstoniaTallinnTepp Kersti
EstoniaTallinnKlepinina Lyudmila
EstoniaTallinnKarro N
EstoniaTallinnKlepinin Aleksandr
EstoniaTallinnShevchuk Igor
FinlandTurkuStier Antoine
FinlandJyvaeskylaeKainulainen Heikki
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GermanyMainzMaull Felicia
GermanyMunichZischka Hans
GermanyWilhelmshavenSalmon Pablo
GermanyMagdeburgSchoenfeld Peter
GermanyMarburgVogt Sebastian
GermanyDĂŒsseldorfGoy C
GermanyCologneWiesner Rudolf J
GreeceHeraklionTavernarakis Nektarios
Greece15771Andreadou Ioanna
GreeceThessalonikiLazou Antigone
GreeceAthensGumeni Sentiljana
GreeceAthensTrougakos Ioannis P
HungaryDebrecenVerebne Tar K
HungarySzegedBoros Mihaly
HungaryBudapestChinopoulos Christos
HungaryBudapestHorvath G
HungarySzegedFerdinandy Peter
HungaryBudapestTretter Laszlo
HungaryBudapestKomlodi Timea
IndiaVaranasiSonkar Vijay K
IndiaLucknowGayen Jiaur
IndiaKollamSuravajhala Prashanth
IndiaNew DelhiThakkar Himani
IndiaHaryanaChakrabarti Sasanka
IndiaNew DelhiVincent Vinnyfred
IndiaHyderabadJha Rajan Kumar
IranTehranShirazi Reza
IranTehranSafaei Zahra
IrelandDublinO'Gorman Donal
IrelandDublinPorter Richard K
IsraelRishon Le ZionHachmo Yafit
IsraelZrifinSova Marina
IsraelBeer ShevaMishmar Dan
IsraelJerusalemSaada Reisch Ann
ItaliaUdineSalvadego Desy
ItalienPadova PDSzabo Ildiko
ItalyCataniaDe Pinto Vito
ItalyPadovaFernandez-Vizarra Erika
ItalyBolognaGasparre G
ItalyCataniaMagri Andrea
ItalyAnconaBattino Maurizio
ItalyBolzano/BozenVolani Chiara
ItalyBariAttimonelli M
ItalySt. LorenzenHarrison David K
ItalyUdineGrassi B
ItalyBolognaGenova Maria Luisa
ItalyCampobassoPallotta Maria Luigia
ItalyRomeScatena Roberto
ItalyBolognaPaterlini S
ItalyMilanoBottoni P
ItalyMilanClementi Emilio
ItalyPadovaViscomi Carlo
ItalyMonserratoIsola Raffaella
ItalyBolognaPorcelli AM
ItalyCataniaMessina Angela
ItalyPadovaBernardi Paolo
ItalyBolzanoZanon Alessandra
JapanSapporoMatsumoto J
JapanItabashi-ku TokyoTanaka Masashi
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KoreaSeoulPak Youngmi Kim
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Korea (South)SeoulLee Hong Kyu
LatviaRigaVolska Kristine
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LatviaRigaStelfa Gundega
LatviaRigaInashkina I
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LatviaRigaLiepins Edgars
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LatviaRigaVilks Karlis
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MaltaMsidaVella Joanna
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NetherlandsGA WageningenGrefte Sander
New ZealandAucklandHickey Anthony J
New ZealandWellingtonBerridge Michael V
New ZealandAucklandWard Marie Louise
New ZealandAucklandKaur Sarbjot
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NorwayOsloEide L
NorwayTrondheimLerfall Joergen
NorwayTromsoeBoardman Neoma T
NorwayTrondheimRognmo O
NorwayBergenTronstad Karl Johan
NorwayBergenHoel Fredrik
NorwayBergenDyrstad Sissel E
NorwayBergenRoesland Gro Vatne
NorwayTrondheimGrill V
NorwayBergenBlindheim Dan Filip
NorwayBergenBerge Rolf K
NorwayBergenPettersen Nitschke Ina Katrine
PolandPoznanJarmuszkiewicz Wieslawa
PolandLodzWatala Cezary
PolandWarszawaJaskiewicz Anna
PolandWarsawDymkowska Dorota
PolandLodzLabieniec-Watala Magdalena
PolandKrakowDembinska-Kiec Aldona
PolandWarsawSzewczyk Adam
PolandWarsawWasilewski M
PolandGdaƄskKaczor Jan Jacek
PolandWarsawBednarczyk Piotr
PolandWarsawSek Aleksandra
PolandWarsawKarkucinska-Wieckowska Agnieszka
PolandWarsawKampa Rafal Pawel
PolandWarsawZablocki Krzysztof
PolandWarsawWieckowski Mariusz R
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PortugalCoimbraGrilo Luis
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Republic of SerbiaBelgradeLalic Nebojsa M
Republic of SerbiaNovi SadAndric Silvana
RussiaYoshkar-OlaDubinin M
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SerbiaBelgradeDjordjevic M
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SerbiaBelgradeMandic M
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SwedenStockholmLarsen Filip J
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SwitzerlandLausanneDonnelly Chris
SwitzerlandLausanneWeger M
SwitzerlandLausanneLagarrigue Sylviane
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SwitzerlandLausanneZalachoras I
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USAWinston-SalemTomar Dhanendra
USAOrlandoPino Maria F
USAFort CollinsChicco Adam J
USAEast LansingBazil Jason N
USALa JollaSchilling Jan M
USAOrlandoSparks Lauren M
USAProvoHancock Chad R
USAChicagoDayanidhi Sudarshan
USARochesterNair K Sreekumaran
USAAuroraMoreau Kerrie
USACorvallisBatterson Philip M
USAGainesvilleLeeuwenburgh Christiaan
USAPittsburghProchownik Edward V
USAWinston-SalemGonzalez-Armenta Jenny L
USAAuroraFord Ellen
USAMilwaukeeDash Ranjan K
USAPhiladelphiaTowheed Atif
USANorfolkLai Nicola
USALittle RockParajuli Nirmala
USAIowa CityChaurasia Bhagirath
USAFairbanksO'Brien Kristin
USAIndianapolisBrozinick Joseph T
USABethesdaSharma Pushpa
USARochesterLanza Ian R
USANew YorkGalkin Alexander
USABaltimoreGonzalez-Freire Marta
USAKansas CitySwerdlow Russell H
USAColorado SpringsJacobs RA
USAIowa CityWagner Brett A
USAAtlantaJang Young Charles
USAWinston-SalemAhn Bumsoo
USAStanfordStary Creed
USADurhamLi Pingan Andy
USAFayettevilleIyer Shilpa
USASt. LouisAbumrad Nada A
USANashvilleWasserman David H
USAAkronCohen Bruce H
USAJupiterTrivigno Catherine
USAEast LansingZhang Yizhu
USADavisHellgren Kim T
USAStillwaterDavis Michael S
USACorvallisRobinson Matthew M
USALos AngelesKwast Kurt E
USABirminghamMoellering Douglas R
USABaton RougeIrving Brian A
USAFayettevilleRao RR
USASan Diego; La JollaMolina Anthony JA
USABaton RougeHand Steven C
USAGainesvilleNeyroud D
USAAnn ArborTyrrell Daniel J
... further results


Comments and discussion

  1. We are mostly interested in two WG: (1) Since we are working mostly with heart and muscles, we are interested in WG 2 - MITOEAGLE data repository in muscle and other tissues. (2) WG 1 - Standard operating procedures and user requirement document: Protocols, terminology, documentation. Since we have an expertise in fatty acid metabolism, we are specially interested in experimental protocols for the evaluation of mitochondrial capacities regarding fatty acid metabolism. Of course our parts of the WG are also in our interest. - Marina Makrecka-Kuka, Edgars Liepinsh (2016).
  2. My role in Mito-EAGLE would be mainly in WG 2 and 4, with a focus on skeletal and cardiac muscle and cultured cardiomyocytes and endothelial cells. I would particularly like to bridge the gap between the group leaders and young investigators, trying to represent the young people who are the active users of the OROBOROS equipment. This will fit in nicely with the goals in WG1. ... Major congratulations on obtaining this beautiful collaborative grant! Very glad to see this network getting the recognition it deserves! Looking forward to being part of this! - Rob C Wuest (2016).
  3. Please, find enclosed my declaration to participate with my team in the following workgroups: WG1, WG2, WG3, WG4. We are now involved and have been in not a distant past – in studying of the following cell /tissue types:
    1. Blood cells, with particular emphasis on platelets and lymphocytes – isolated from animals and humans.
    2. Endothelial cells, fibroblasts, neurocytes (neuroblastoma), astrocytes, cancer cell lines – predominantly cultured.
    3. Hepatocytes, cardiomyocytes, cell isolated from brain – isolated from lab animals. - Cezary Watala (2016).
  4. I have already contacted the portuguese CNC to nominate me for the MC of theaction. Concerning my active participation, taking into account the type of work we do in my lab I could be included in all WGs. As you know we work with mitochondria from liver, muscle and fat, as well as cultured cells from different origins (WG2-4). The elaboration of SOPs (WG1) we can certainly contribute (see the book I edited on Mitochondrial Bioenergetics and in which you contribute a chapter). I believe that everybody can be part of the WG5, but as the coordinators of the action, you and Sandra should decide what is best for the success of the action. - Carlos Palmeira (2016).
  5. I would propose my participation in the WG1: Standard operating procedures and user requirement document: Protocols, terminology, documentation, considering that the goal of WG1 is to establish an integrated and analytic environment linking mitochondrial respiration with external data (cell physiology, anthropometry, spiroergometry, lifestyle, genomics) in the context of physical fitness evaluation and clinical diagnostics. I could give my active contribution in the phase of making platform that will aggregate the Action’s complete knowledge and provides the ability to make diagnostic profiling associated with diseases in particular tasks:
    1. Develop reccomendations for quality control, data reporting and data sharing beyond the published record. Develop concepts on Open Access and institutionalised service for data management, data mining and health-care conforming standards of data interpretation
    2. Provide a summary on strategic dissemination and an education programme for MITOEAGLE.
    3. Considering that we are in process of buying the oxygraph, thus broading capacities of my lab, I would be happy to open the door of my new lab for the innovative inter-laboratory ring test experiments and together with my team contribute in that phase of the MITOEAGLE Action. I look forward to the establishment of MitoGlobal EAGLE network where, as stated in the MoU, researchers will collaborate on mapping mitochondrial physiology and medicine. The creation of such a unique well-coordinated network of senior researchers and young investigators will definitely put an added value to existing data and publications, will increase quality and validity of the research, will bring new possibilities of data sharing and data mining and will hopefully bring us to the era of more economical research by saving resources through standardised and harmnonised protocols, where the measuremnts will not be wasted due to lack of comparability. - Nebojsa Lalic (2016).
  6. Our research interest is oriented to reproductive endocrinology; especially to mechanisms that govern steroidogenesis of testicular Leydig cells in disturbed homeostasis. We use several in vivo models:
    1. stress -/+ systemic or intratesticular blockade of different stress receptors (alpha1ADR; betaADR; GR)
    2. hypogonadal-hypogonadism -/+ testosterone-replacement therapy
    3. androgens anabolics treatment -/+ blockade od AR
    4. aged rats -/+ Viagra-treatment
    5. biological clock - Silvana Andric (2016).
  7. I took a look to the MoU and the different working groups. You know well my research focus and having this into account I am interested in actions related to Working group 1 (Respirometric reference protocols, Interlaboratory proficiency test, Instrumental platforms). Working group 2 and 3: I have generated multiple mitochondrial respiration data sets in different mouse tissues (mainly in skeletal muscle, hypothalamus, liver and white adipose tissue). Currently we are also performing these assays in white adipose tissue from human patients. Hence I am interested in all milestones of WG 2 and 3. WG 5 is related to WG 1 and as you know I have interest in training, dissemination and also together with my collaborators (if needed) we could help with data sets and a data interpretation. Overall, I have a general interest on this Action and my active role in MITOEAGLE could be discussed. I could be of help participating in some of the tasks where my expertise and interest fit best. We will be forming and interdisciplinary research group with four group leaders: JC Perales, R Guimera, M Sales-Pardo and PM Garcia-Roves with two different affiliations, University of Barcelona (JCP and PMG-R - Energy metabolism) and University Rovira I Virgili (RG and MS – Data base, statistics, data mining). - Pablo M Garcia-Roves (2016).
  8. I will be pleased to contribute to the tasks of WG1 by developing interlaboratory proficiency tests and instrumental platform comparison. Moreover, as a (potential) MC member of MitoEAGLE I can also offer visibility to the Action itself (i.e. WG5: MITOEAGLE dissemination and training, according to mitoglobal.org webpages) by establishing new interactions with the International Coenzyme Q10 Association (ICQA) where I act as a member of the Executive Committee. ICQA organizes biennal conferences on new highlights of Coenzyme Q research. In 2015, we held the conference in Bologna (http://conference2015.wix.com/icqaconference) and we included in the program also some scientific sessions dedicated to mitochondrial bioenergetics and diseases. I will be pleased to enforce cooperation between ICQA and MitoEAGLE. - Maria Luisa Genova (2016).
  9. We found the scientific content and objectives of the call very interesting and compatible with our wide expertise on oxysterol analysis in food and biological systems. Our group has a large experience on lipid composition and their degradation products (volatile and non-volatile), as well as on sensory analysis. Moreover, we are currently involved in the H2020-GERI-2014-1 project "PLOTINA" ("Promoting gender balance and inclusion in research, innovation and training") with Prof. Gallina Toschi (in cc) as coordinator; the project actually includes gendered case studies where gender and sex variables are considered. You can find further information about our expertises, publications and the PLOTINA project at the following webpages: https://www.unibo.it/sitoweb/maria.rodriguez/, https://www.unibo.it/sitoweb/tullia.gallinatoschi/, http://www.unibo.it/en/research/projects-and-initiatives/research-projects-horizon-2020-1/plotina - Maria Teresa Rodriguez Estrada (2016).
  10. As you know, our current/developing interests are with "evolution" (species comparisons) and "environment" (hypoxia and cold exposure), but have also experience and interest in assessing effects of "lifestyle" (diet, exercise) and "aging" as well (in rodents). - Adam J Chicco (2016).
  11. Congratulations on the considerable progress with MITOEAGLE! I am keen to participate in this exciting project and I’m sure I can make a valuable contribution to it's success. I have extensive experience performing respirometry assays in human muscle biopsies, myoblasts/tubes and mouse tissues in the contexts of aging, obesity, exercise and inactivity. I feel that I could contribute to any of the five working groups, but particularly to WG2, WG4, and WG5. I am also happy and willing to serve on the Management Committee if needed. Again, congratulations on organizing such an exciting project. - Paul M Coen (2016).
  12. I would be interested to be involved with WG1 and WG2. In particular, I am interested in contributing to developing protocols for multicenter quality control among labs, and for permeabilized muscle bundle respirometry. - Harry B Rossiter (2016).
  13. I think that we could contribute via participation in the evaluation of the protocols, and helping to develop them further. In addition, we have been working on the establishing a database that would allow us to keep protocol details, cell isolation and several other aspects. There is nothing very advanced, but we could contribute to establishing such data collection practice. In addition, we, as opposed to many others, happen to use Strathkelvin respirometer. This alternative hardware would allow us to verify whether the protocols work on them as well. - Marko Vendelin (2016).


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