Template:SUIT text D052: Difference between revisions
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The SUIT-012 O2 ce-pce D052 protocol specifically focuses on assessing the coupling control ([[LEAK | The SUIT-012 O2 ce-pce D052 protocol specifically focuses on assessing the coupling control ([[LEAK respiration|''L'']]-[[Oxidative phosphorylation| ''P'']]-[[ET-capacity| ''E'']]) with NADH-linked substrates ([[PM-pathway control state|PM]] and [[PGM]]). Addition of [[Glutamate|G]] enables evaluating the contribution of this substrate in NADH-supported [[Oxidative phosphorylation| OXPHOS]] respiration, which may be relevant in the presence of [[glutamate-anaplerotic pathway control state]]. SUIT-012 can be extended with the CIV assay module. | ||
Revision as of 10:47, 8 June 2020
The SUIT-012 O2 ce-pce D052 protocol specifically focuses on assessing the coupling control (L- P- E) with NADH-linked substrates (PM and PGM). Addition of G enables evaluating the contribution of this substrate in NADH-supported OXPHOS respiration, which may be relevant in the presence of glutamate-anaplerotic pathway control state. SUIT-012 can be extended with the CIV assay module.
