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Difference between revisions of "Bioblast alert 2015"

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[[Image:BB-Bioblast.jpg|left|30px|link=Bioblast:About|Bioblast wiki]]
[[File:Bioblast alert.jpg|240px|right|link=Bioblast_alert|Bioblast alert]]


'''Bioblast alert''' is prepared by the [[Bioblast editorial board]] to draw attention to specific topics on the '''Bioblast wiki'''.
'''[[Bioblast alert|back to "Bioblast alert" main page]]'''
'''Bioblast alert''' is for information purposes, it is not intended to be an advertisement. 
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Your contributions are very welcome.


== Bioblast alert 2012 (03): 2012-03-23 ==
=== Bioblast alert 2015(01): 2015-01-01 ===
'''MitoPedia topic: [[Permeabilized_muscle_fibres#Oxygen_dependence_of_ROS_production_-_are_permeabilized_fibres_a_valid_model.3F|Oxygen dependence of ROS production - are permeabilized fibres a valid model?]]''' / [[Talk:Permeabilized muscle fibres|Discussion]]


'''High-resolution respirometry in permeabilized muscle fibres: drosophila vs. sandworm'''
[[Image:BB-Bioblast.jpg|left|30px|link=Gentle Science|Gentle Science]]
# Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol Pichaud N, Rioux P, Blier PU (2012) In situ quantification of mitochondrial respiration in permeabilized fibers of a marine invertebrate with low aerobic capacity. [[Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol|Comp Biochem Physiol A Mol Integr Physiol Epub ahead of print.]]
# Pichaud N, Ballard JWO, Tanguay RM, Blier PU (2011)Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes. [[Pichaud 2011 Am J Physiol Regul Integr Comp Physiol|Am J Physiol Regul Integr Comp Physiol 301: R48-R49.]]


== Bioblast alert 2012 (02): 2012-03-06 ==
[[Gentle_Science#Bioenergetics_-_Arts_meets_Gentle_Science |'''Bioenergetics - Arts meets Gentle Science''']] - Bioenergetics Exhibition, March 15-June 17, 2015, Science Museum of Virginia, US - a Gentle Science project initiated by [[Iyer S |Shilpa Iyer]].
* '''50 Years ago''': '''Nick Holonyak''', considered as the "father of the light-emitting diode", developed the first practical '''visible-spectrum LED in 1962'''. ''Which colour? What is a'' '''LED'''''?'' >>> see '''[[Light emitting diode|Glossary: Fluorescence]]'''


'''Mitochondrial dys/function in obesity vs. anorexia''':
* Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlén M, Ekström TJ, Davisson MT, Hökfelt TG, Schalling M, Johansen JE (2011) Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. [[Lindfors 2011 Proc Natl Acad Sci U S A|Proc Natl Acad Sci U S A 108: 18108-18113]].
* Holmstrom MH, Iglesias-Gutierrez E, Zierath JR, Garcia-Roves PM (2012) Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. [[Holmstrom 2012 Am J Physiol Endocrinol Metab|Am J Physiol Endocrinol Metab Epub ahead of print]].


== Bioblast alert 2012 (01): 2012-02-27 ==
[[Image:Logo-MiP2014.jpg|left|55px|link=MiP2015|MiPArt by Odra Noel]]
» '''MiP''schools'' 2015''': »» [[MiPschool Cape Town 2015 |'''Cape Town ZA, March 24-28''']] »» [[MiPschool London 2015 |'''London UK, April 20-25''']] »» [[MiPschool Greenville 2015 |'''Greenville US, August 10-14''']].


Two exciting publications on '''mitochondrial [[p50]]''', apparent [[excess capacity]] of cytochrome c oxidase, '''[[basal metabolic rate]]''', [[P/O ratio]]s and ergometric [[efficiency]]:
» [[MiP2015 |'''Mitochondrial Physiology Conference MiP2015, Sep 7-11''']], Luční Bouda, Czech Republic.
:# Larsen FJ, Schiffer TA, Sahlin K, Ekblom B, Weitzberg E, Lundberg JO (2011) Mitochondrial oxygen affinity predicts basal metabolic rate in humans. [[Larsen_2011_FASEB_J|FASEB J 25: 2843-2852]].
:# Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Dietary inorganic nitrate improves mitochondrial efficiency in humans. [[Larsen_2011_Cell_Metab|Cell Metab 13: 149-159]].


== Bioblast alert 2011 (04): 2011-12-24 ==


* '''Congratulations''' to [[Pesta D|Dr. Dominik Pesta]], for receiving his degree of a PhD at the Medical University of Innsbruck! (Jan 2012)
[[Image:BB-Bioblast.jpg|20px|link=Bioblast:About|Bioblast wiki]] '''[[Bioblast track]]''' - evolving hot Bioblast topics: reflections at the beginning of the New Year.
* [[Bioblast editorial board]] - [[Talk:Bioblast editorial board|Why a wiki editorial board?]]  
* '''[[SUIT protocol]]s for HRR: from intact cells to permeabilized muscle fibres''':
::[[Pesta 2012 Methods Mol Biol|Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibres from small biopisies of human muscle. Methods Mol Biol 810: 25-58.]]


== Bioblast alert 2011 (03): 2011-11-24 ==
*'''Fluorometry combined with high-resolution respirometry''': Light guide inserted into the chamber through a black PEEK stopper<ref>[[Anderson 2011 Am J Physiol Heart Circ Physiol|Anderson EJ, Rodriguez E, Anderson CA, Thayne K, Chitwood WR, Kypson AP (2011) Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol 300: H118-124.]]</ref>, or optical probe operated through the O2k-glass window<ref>[[Hickey 2012 J Comp Physiol B|Hickey AJ, Renshaw GM, Speers-Roesch B, Richards JG, Wang Y, Farrell AP, Brauner CJ (2012) A radical approach to beating hypoxia: depressed free radical release from heart fibres of the hypoxia-tolerant epaulette shark (''Hemiscyllum ocellatum''). J Comp Physiol B [Epub ahead of print] ]]</ref>.
<references/>


*'''[[Talk:Fluorometry|Fluorometry versus fluorimetry]]''' - term of the week. >>>New '''[[Glossary: Fluorometry]]''' - high-resolution terminology.
'''<big><big><big>HRR</big></big></big> - high-resolution respirometry''' was established 20 years ago: [[Gnaiger 1995 J Bioenerg Biomembr |Control of mitochondrial and cellular respiration by oxygen. J Bioenerg Biomembr 1995.]]


== Bioblast alert 2011 (02): 2011-11-17 ==


*'''[http://www.oroboros.at/index.php?ioc64 O2k-Workshop IOC64 - Centre for Cellular and Molecular Biology, Hyderabad, India]: 2011-12-08'''.
=== Bioblast alert 2015(02): 2015-04-28 ===


*O2k-Publication: '''Heart failure and mitochondrial dysfunction'''. Increased OXPHOS capacity after cold preservation of the human heart – a paradox resolved by a dyscoupling mechanism.  
* Gentle Science: The '''Vancouver Protocol''' carries the spirit of Gentle Science. Do involved editors, authors and peer reviewers know that? »[[Gentle_Science#The_Vancouver_Protocol.2C_ICMJE.2C_and_Gentle_Science |''more details'']]
::[[Lemieux 2011 Int J Biochem Cell Biol|Lemieux H, Semsroth S, Antretter H, Hoefer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43: 1729–1738]]. >>> [[Talk:Lemieux 2011 Int J Biochem Cell Biol|Discussion: Complementary results on the PGC-1a pathway]].
* [[MitoGlobal Events]]: '''[[UMDF2015 |Mitochondrial Medicine, UMDF2015]]: Washington DC US, 2015 Jun 17-20'''.
* [[MitoGlobal Organizations]]: Amy Goldstein ([[Mitochondrial_Medicine_Society|Mitochondrial Medicine Society]]) created the '''Mitochondrial Global Networks map'''. »[http://www.mitosoc.org/clinics ''see the map''].
* Weissig V, Edeas M, eds (2015) Mitochondrial medicine: probing mitochondrial function. [[Weissig_2015_Methods_Mol_Biol_I |Methods Mol Biol 1264:1-480]].
* MitoPedia: '''What is wrong with the RCR?''' »''Find out:'' [[Image:j--P.jpg|50 px|link=OXPHOS-coupling efficiency |OXPHOS-coupling efficiency]] [[OXPHOS-coupling efficiency]]


*'''[[Tissue storage]]''' on ice is possible for limited periods of time (several hours) with preservation of mitochondrial respiratory function, as evaluated with [[SUIT protocol]]s. ([[Scientific service]])


*'''[[Uncoupled]], [[non-coupled]], [[dyscoupled]]''' - term of the week: a hallmark of high-resolution respirometry is a matching high-resolution terminology.
=== Bioblast alert 2015(03): 2015-07-03 ===
::[[Talk:Uncoupled respiration|Evaluate an example of low-resolution terminology]]: '''''[[Dyscoupled respiration|Uncoupling]]''' was studied in stressed cells by measurement of coupled respiration, evaluation of '''[[LEAK|uncoupled]]''' respiration after inhibition with oligomycin, and FCCP titration to quantify '''[[non-coupled|uncoupled]]''' respiration''.


[[Image:MitoPedia.jpg|40px|link=MitoPedia|MitoPedia]] » '''[[Melatonin |Melatonin beyond the clock]]'''


== Bioblast alert 2011 (01): 2011-11-11 ==
[[Image:MitoPedia.jpg|40px|link=MitoPedia|MitoPedia]] [[Image:R.jpg|link=ROUTINE respiration|ROUTINE]] - [[Image:L.jpg|link=LEAK respiration|LEAK]] - [[Image:E.jpg|link=ET capacity|ETS]] - [[Image:ROX.jpg|link=Residual oxygen consumption|ROX]]: this is the 'phosphorylation control protocol' (PCP) for intact cells - or better '''[[coupling-control protocol]]''' (CCP)?


*'''[http://www.oroboros.at/index.php?ioc66 O2k-Fluorometry Workshop IOC66]''': 2012-03-15 to 16. OROBOROS INSTRUMENTS, Innsbruck, Austria.  The first series of the '''[[O2k-Fluorescence LED2-Module]]''' will be delivered in '''April 2012''', for orders received by end of January 2012.  
» Special Issue on [[Media:Mitochondrial_Biology_Toxicology_and_Medicine.pdf | Mitochondrial Biology, Toxicology, and Medicine]] by Ryan J. Mailloux, University of Ottawa,Ottawa, Canada ([mailto:rmaillou@uottawa.ca rmaillou@uottawa.ca]) - deadline August 14, 2015.
*O2k-Publication: A key question on the separation of '''qualitative versus quantitative change of mitochondrial function''' is addressed in a new O2k-Publication. Does training induce mild uncoupling? Are sedentary humans healthy controls?
 
::[[Pesta_2011_Am J Physiol Regul Integr Comp Physiol|Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301: R1078–R1087]].
» [[MitoGlobal Events]]: [[MiP2015]] - early registration deadline July 14!
*[[ETS capacity]] plays a key role in such analyses, which cannot be achieved quantitatively without careful '''[[Optimum uncoupler concentration|uncoupler titrations]]'''. ([[Scientific service]])
 
*'''[[Basal respiration]]''' - term of the month: a hallmark of high-resolution respirometry is a matching high-resolution terminology.
 
=== Bioblast alert 2015(04): 2015-08-24 ===
 
[[Image:Logo-MiP2014.jpg|40px|link=MiP2015|MiPArt by Odra Noel]] [[MitoGlobal Events]]: Programme '''Mitochondrial Physiology Conference, CZ, Sept 2015''' now online: '''»[[MiP2015]]«'''. Last-minute registrations are encouraged - a special opportunity for MiP''members'', students and young investigators - no surcharge for late registration.
 
 
[[Image:BB-Bioblast.jpg|30px|link=Bioblast:About|Bioblast wiki]] Send your favourite '''» [[Bioblast picture of the month]]'''.
 
[[Image:MitoGlobal.jpg|40px|link=Mitochondrial_Global_Network|MitoGlobal]] 5 years ago: the '''Bioblast Boost''' » [[Bioblast:About]]
 
[[Image:MitoPedia.jpg|40px|link=MitoPedia|MitoPedia]] » [[MitoPedia: Respiratory states]]: apparent excess capacities of respiration [[Image:ExP.jpg|60 px|link=Excess E-P capacity|Excess ''E-P'' capacity]] [[Image:ExR.jpg|60 px|link=Excess E-R capacity|Excess ''E-R'' capacity]]
 
 
 
== Bioblast alert - previous issues ==
* [[Bioblast alert 2015]]
* [[Bioblast alert 2014]]
* [[Bioblast alert 2013]]
* [[Bioblast alert 2012]]
* [[Bioblast alert 2011]]
 
 
[[Category:Gentle Science]]

Latest revision as of 15:01, 8 June 2020

Bioblast alert 2015

Bioblast wiki
Bioblast alert

back to "Bioblast alert" main page

Bioblast alert 2015(01): 2015-01-01

Gentle Science

Bioenergetics - Arts meets Gentle Science - Bioenergetics Exhibition, March 15-June 17, 2015, Science Museum of Virginia, US - a Gentle Science project initiated by Shilpa Iyer.


MiPArt by Odra Noel

» MiPschools 2015: »» Cape Town ZA, March 24-28 »» London UK, April 20-25 »» Greenville US, August 10-14.

» Mitochondrial Physiology Conference MiP2015, Sep 7-11, Luční Bouda, Czech Republic.


Bioblast wiki Bioblast track - evolving hot Bioblast topics: reflections at the beginning of the New Year.


HRR - high-resolution respirometry was established 20 years ago: Control of mitochondrial and cellular respiration by oxygen. J Bioenerg Biomembr 1995.


Bioblast alert 2015(02): 2015-04-28


Bioblast alert 2015(03): 2015-07-03

MitoPedia » Melatonin beyond the clock

MitoPedia ROUTINE - LEAK - ETS - ROX: this is the 'phosphorylation control protocol' (PCP) for intact cells - or better coupling-control protocol (CCP)?

» Special Issue on Mitochondrial Biology, Toxicology, and Medicine by Ryan J. Mailloux, University of Ottawa,Ottawa, Canada ([email protected]) - deadline August 14, 2015.

» MitoGlobal Events: MiP2015 - early registration deadline July 14!


Bioblast alert 2015(04): 2015-08-24

MiPArt by Odra Noel MitoGlobal Events: Programme Mitochondrial Physiology Conference, CZ, Sept 2015 now online: »MiP2015«. Last-minute registrations are encouraged - a special opportunity for MiPmembers, students and young investigators - no surcharge for late registration.


Bioblast wiki Send your favourite » Bioblast picture of the month.

MitoGlobal 5 years ago: the Bioblast Boost » Bioblast:About

MitoPedia » MitoPedia: Respiratory states: apparent excess capacities of respiration Excess E-P capacity Excess E-R capacity


Bioblast alert - previous issues