Template:Keywords: Coupling control: Difference between revisions
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! | ! Respiratory rate !! Definition !! Icon | ||
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| [[OXPHOS-capacity]] || ''P'' = ''P´''-''Rox'' || [[File:P.jpg |link=OXPHOS-capacity]] | | [[OXPHOS-capacity]] || ''P'' = ''P´''-''Rox'' || [[File:P.jpg |link=OXPHOS-capacity]] | ||
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| [[ROUTINE-respiration]] || ''R'' = ''R´''-''Rox'' || [[File:R.jpg |link=ROUTINE-respiration]] | | [[ROUTINE-respiration]] || ''R'' = ''R´''-''Rox'' || [[File:R.jpg |link=ROUTINE-respiration]] | ||
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| [[ET-capacity]] || ''E'' = ''E´''-''Rox'' || [[File:E.jpg |link=ET-capacity]] | | [[ET-capacity]] || ''E'' = ''E´''-''Rox'' || [[File:E.jpg |link=ET-capacity]] || » [[Noncoupled respiration]] - [[Uncoupler]]<ref>Gnaiger E. Is respiration uncoupled - noncoupled - dyscoupled? Mitochondr Physiol Network. »[[Uncoupler]]«</ref> | ||
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| [[LEAK-respiration]] || ''L'' = ''L´''-''Rox'' || [[File:L.jpg |link=LEAK-respiration]] || » [[LEAK-state with ATP]] | |||
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| || || || » [[LEAK-state with oligomycin]] | |||
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| | | || || || » [[LEAK-state without adenylates]] | ||
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| [[Residual oxygen consumption]] ''Rox'' || ''L'' = ''L´''-''Rox'' || [[File:ROX.jpg |link=Residual oxygen consumption]] | | [[Residual oxygen consumption]] ''Rox'' || ''L'' = ''L´''-''Rox'' || [[File:ROX.jpg |link=Residual oxygen consumption]] | ||
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:::* Chance and Williams nomenclature: respiratory states | :::* Chance and Williams nomenclature: respiratory states | ||
::::» [[State 1]] | ::::» [[State 1]] —» [[State 2]] —» [[State 3]] —» [[State 4]] —» [[State 5]] | ||
=== Flux control ratios related to coupling in mt-preparations and living cells === | === Flux control ratios related to coupling in mt-preparations and living cells === | ||
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:::» [[Coupling-control ratio]] | :::» [[Coupling-control ratio]] | ||
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! ''FCR'' !! Definition !! Icon | |||
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| [[L/P coupling control ratio |''L/P'' coupling control ratio]] || ''L/P'' || [[Image:L over P.jpg|50 px|link=L/P coupling control ratio |''L/P'' coupling control ratio]] || » [[Respiratory acceptor control ratio]], RCR = ''P/L'' | |||
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| [[L/R coupling control ratio |''L/R'' coupling control ratio]] || ''L/R'' || [[Image:L over R.jpg|50 px|link=L/R coupling control ratio |''L/R'' coupling control ratio]] | |||
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| [[L/E coupling control ratio |''L/E'' coupling control ratio]] || ''L/E'' || [[Image:L over E.jpg|50 px|link=L/E coupling control ratio |''L/E'' coupling control ratio]] || » [[Uncoupling-control ratio]], UCR = ''E/L'' | |||
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| [[P/E control ratio |''P/E'' control ratio]] || ''P/E'' || [[Image:P over E.jpg|50 px|link=P/E control ratio |''P/E'' control ratio]] | |||
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| [[R/E control ratio |''R/E'' control ratio]] || ''R/E'' || [[Image:R over E.jpg|50 px|link=R/E control ratio |''R/E'' control ratio]] | |||
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| [[net P/E control ratio |net ''P/E'' control ratio]] || (''P-L'')/''E'' || [[Image:NetP over E.jpg|60 px|link=net P/E control ratio |net ''P/E'' control ratio]] | |||
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| [[net R/E control ratio |net ''R/E'' control ratio]] || (''R-L'')/''E'' || [[Image:NetR over E.jpg|60 px|link=net R/E control ratio |net ''R/E'' control ratio]] | |||
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=== Net, excess, and reserve capacities of respiration === | === Net, excess, and reserve capacities of respiration === |
Revision as of 18:50, 10 November 2020
4-compartmental OXPHOS model. (1) ET capacity E of the noncoupled electron transfer system ETS. OXPHOS capacity P is partitioned into (2) the dissipative LEAK component L, and (3) ADP-stimulated P-L net OXPHOS capacity. (4) If P-L is kinetically limited by a low capacity of the phosphorylation system to utilize the protonmotive force pmF, then the apparent E-P excess capacity is available to drive coupled processes other than phosphorylation P» (ADP to ATP) without competing with P».
- Bioblast links: Coupling control - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
Mitochondrial and cellular respiratory rates in coupling control states
Respiratory rate | Definition | Icon | |
---|---|---|---|
OXPHOS-capacity | P = P´-Rox | ||
ROUTINE-respiration | R = R´-Rox | ||
ET-capacity | E = E´-Rox | » Noncoupled respiration - Uncoupler[1] | |
LEAK-respiration | L = L´-Rox | » LEAK-state with ATP | |
» LEAK-state with oligomycin | |||
» LEAK-state without adenylates | |||
Residual oxygen consumption Rox | L = L´-Rox |
FCR | Definition | Icon | |
---|---|---|---|
L/P coupling control ratio | L/P | » Respiratory acceptor control ratio, RCR = P/L | |
L/R coupling control ratio | L/R | ||
L/E coupling control ratio | L/E | » Uncoupling-control ratio, UCR = E/L | |
P/E control ratio | P/E | ||
R/E control ratio | R/E | ||
net P/E control ratio | (P-L)/E | ||
net R/E control ratio | (R-L)/E |
Net, excess, and reserve capacities of respiration
- Net OXPHOS-capacity P-L, P-L
- Net ROUTINE-activity R-L, R-L
- Net ET-capacity E-L, E-L
- ET-excess capacity E-P, E-P
- ET-reserve capacity E-R, E-R
- » Flux control efficiency jZ-Y
- OXPHOS-coupling efficiency P-L, jP-L = (P-L)/P = 1-L/P
- ROUTINE-coupling efficiency R-L, jR-L = (R-L)/R = 1-L/R
- ET-coupling efficiency E-L, jE-L = (E-L)/E = 1-L/E
- ET-excess control efficiency E-P, jE-P = (E-P)/E = 1-P/E
- ET-reserve control efficiency E-R, jE-R = (E-R)/E = 1-R/E
General
- » Background state
- » Basal respiration
- » Baseline state
- » Coupling-control protocol
- » Dyscoupled respiration
- » Dyscoupling
- » Electron leak
- » Electron-transfer-pathway state
- » Level flow
- » Metabolic control variable
- » Oxidative phosphorylation
- » Oxygen flow
- » Oxygen flux
- » Permeabilized cells
- » Phosphorylation system
- » Proton leak
- » Proton slip
- » Reference state
- » Respiratory state
- » Static head
- » Uncoupling