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MiP2023 Obergurgl AT
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» Book of abstracts: MiP2023 Bioenerg Commun
Mitochondrial Physiology Society (2023-07-27) MitoGlobal
Abstract: MiP2023, Obergurgl, Austria, 2023.
Feedback from participants
- The MiP2023 conference was hands down the best conference I have ever attended. - Granata Cesare, DE
- Thank you again for the wonderful event that was MIPSchool and the MIPconference. It was a wonderful experience for me, all the contact with different researchers, such as Anthony Moore, Leonid Sazanov, Erika Fernández-Vizarra, among others. As well for your hospitality and reception. THANK YOU VERY MUCH FOR EVERYTHING. 😊😊😊 - Othonicar Murilo F, BR
- The conference was wonderful as usual - thanks so much for all you do to make these events such a success! :) It was great to catch up with you [Verena], Erich and my other friends in the MiP community. I'm already looking forward to the next event, but back to regular work first! - Chicco Adam J, US
- The lectures dealt with a highly relevant topic from the perspective of mitochondrial physiology, a highly specialized subject but with a very practical aspect (diagnostic tools, metabolic adaptations following therapeutic interventions, etc.). The atmosphere was very friendly and, as at every MiPConference, I met new scientists and made new friends. - Votion Dominique-Marie, BE
- Congratulations on another great meeting. The quality of the presentations was outstanding. - Molina Anthony JA, US
- I wanted to send a special thank you for the outstanding organization and hospitality at the conference. The time and efforts you dedicated to make this a successful event resulted in a scientifically stimulating symposium and a wonderful social and nature experiences. Both Linsey and I felt personally welcomed to Obergurgl and to the conference and enjoyed every moment. Shirihai Orian, US
- The MiPconference 2023 was excellent and I was pleased to participate. - Hand Steven C, US
- I really liked the "walk and talk" sessions and overall environment and discussions. - Anonymous participant
- The networking was great! - Anonymous participant
- I enjoyed the sessions on Lifestyle and Mitoalterations in Obesity as well as on Nutrition and Lifestyle in MitObesity. - Anonymous participant
- The topics of Mitoalterations associated with lifestyle, obesity or by nutrition were great! - Anonymous participant
| Question | Rating (average) 1-5 |
|---|---|
| In how far were your interests covered in the MiPconference? 1 (not covered) to 5 (all interests covered) | 4.6 |
| Presentation of lectures in terms of content: 1 (not understandable) to 5 (very understandable) | 4.6 |
| Presentation of lectures in terms of language: 1 (not understandable) to 5 (very understandable) | 4.6 |
| What is your overall rating of the MiPconference 2023 from 1 (poor) to 5 (excellent)? | 4.6 |
Impressions from MiP2023
Group photo MiP2023
Excursion to the top of Hohe Mut, with a view to 21 ‘Dreitausender’.
Exploring nature.
MiP2023 runners team.
Discussions about science and art surrounded by epic scenery
Excitement for the performance of Trachtengruppe Umhausen.
Tyrolean dance performed by Trachtengruppe Umhausen.
Performance by Trachtengruppe Umhausen
Performance by Trachtengruppe Umhausen
Student travel awards handed over by Luiza Cardoso (left), Alba Timon-Gomez and Verena Laner (right)
Invited speakers group photo
Orian Shirihai and Atan Gross received Nick Lane’s latest book for being the most active participants in the discussions.
The newly elected and confirmed Executive MiPcommittee, serving until 2028.
Walk and Talk – Zirbenweg Obergurgl with view to the waterfall.
Via Ferrata/Klettersteig ‘Zirbensteig’.
A short break during the Walk and Talk.
Venue
- University Center Obergurgl
- Gaisbergweg 5
- 6456 Obergurgl
- Tyrol, Austria
- Support for the MiPconference 2023 is acknowledged (alphabetical order):
- We invite cooperating scientific societies and institutions to cooperate and support the MiPconference 2023.
Presentation guidelines
- Oral
- Duration for invited speakers: 20 min (+5 min discussion)
- Duration oral presentations selected from abstracts: 10 min (+5 min discussion)
- Aspect ratio for slides: 16:9
- Use either PowerPoint or Keynote
- A laptop for your presentation is provided
- If you work with a Mac please bring your own computer
- Ensure you bring an adapter for your device with HDMI connection, VGA to HDMI is provided
- Please make sure you do not go overtime
- Media check to hand in your slides in the morning of the conference is possible
- Posters
- Please bring your poster in size A0, portrait.
- Posters
- BEC Special Issue
- We invite original articles to be published in a special issue of Bioenergetics Communications on ‘mitObesity and Healthy Aging’:
- » BEC author guidelines
Program
- The topic of the 15th MiPconference is: Bioenergetics Communications on mitObesity and Healthy Aging.
- Furthermore, the General Assembly of the MiPsociety will take place during the conference.
- Program pdf
- Program-at-a-glance
- 2023-Jul-27 Thursday Arrival
- 17:30 Welcome reception
- 19:00 Dinner
- 20:30 Opening
- 20:30 – 21:30 Erich Gnaiger: From globesity to mitObesity.
- 2023-Jul-28 Friday
- 08:30 Session A1. Lifestyle and mitoalterations in obesity
- Session chairs: Verena Laner and Orian Shirihai
- 08:30 – 08:55 Anthony Molina: Targeting exercise intolerance in older, obese, heart failure patients.
- 08:55 – 09:10 Heather Petrick: Age- and sex-related differences in mitochondrial ADP sensitivity in human skeletal muscle.
- 09:10 – 09:25 Ana Valencia: T-cell mitochondria exhibit a functional decline with obesity that is aggravated by weight loss.
- 09:25 – 09:50 Tal Yardeni: The host immune system and the gut microbiota are regulated by the mitochondrial DNA.
- 09:50 Coffee/tea break
- 10:25 Session A2. Exercise, training and hypoxia
- Session chairs: Dominique-Marie Votion and Alexander Karabatsiakis
- 10:25 – 10:50 Steen Larsen: Mitochondrial adaptations to weight loss – lifestyle, surgery or medication.
- 10:50 – 11:05 Henver Brunetta: Chronic aerobic training reverts the negative effects of high-fat high-sucrose diet on the left ventricle of adipocyte-specific DICER knockout mice in association with improved mitochondrial function.
- 11:05 – 11:20 Daniel Sadler: Early life exercise training counters metabolic perturbations imparted by low parental cardiorespiratory fitness.
- 11:20 – 11:45 Bengt Kayser: Obesity and hypoxia: from etiology to therapy.
- 11:45 – 12:00 Steven Hand: Oxidative stress and repetitive metabolic transitions: Challenges due to lifestyle of invertebrate extremophiles.
- 12:00 - 15:30 Walk & Talk
- 15:30 Session A3. Nutrition and lifestyle in mitObesity
- Session chairs: Alba Timon-Gomez and Adam Chicco
- 15:30 – 15:55 Atan Gross: M(a)TCH2-ing up metabolism and apoptosis at the MOMbrane.
- 15:55 – 16:20 Graham Holloway: Mitochondrial bioenergetics as a nexus-point for the beneficial effects of nitrate in diverse tissues.
- 16:20 – 16:35 Patricia Owesny: Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.
- 16:35 – 16:50 Pavla Stankova: Effect of telmisartan on nutritionally induced nonalcoholic steatohepatitis in mice.
- 16:50 Coffee/tea break
- 17:25 Session A4. Adipose tissue and fatty acid oxidation
- Session chairs: Luiza Cardoso and Pablo Garcia-Roves
- 17:25 – 17:50 Petr Zouhar: Major site of non-shivering thermogenesis: brown fat or skeletal muscle?
- 17:50 – 18:05 Lukas Alan: Dynamic complexomic analysis reveals a role for Von Willebrand Domain-containing Protein 8 (Vwa8) in mitochondrial morphology and substrate preference.
- 18:05 – 18:20 Lisa Guerrier: Human white adipose tissue mitochondrial respiration: effect of body composition.
- 18:20 – 18:45 Peter Schoenfeld: A view on brain's problem with fatty acid burning.
- 19:00 Dinner
- 20:30-21:30 Poster session
- Lukas Alan: Dynamic complexomic analysis reveals a role for Von Willebrand Domain-containing Protein 8 (Vwa8) in mitochondrial morphology and substrate preference.
- Daria Barkova: Effects of short term and long term aerobic-strength training on muscle metabolism in the elderly.
- Attila Kolonics: Accelerated epigenetic changes may contribute to the development of metabolic syndrome revealed by NADH FLIM.
- Murilo Othonicar: Mitochondrial alternative enzymes and supercomplexes: functional and evolutionary insights.
- Patricia Owesny: Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.
- Howard Phang: Screening marine natural products for bioenergetic effects in human cell models.
- Sarah Piel: Effect of dimethyl fumarate on cerebral mitochondrial metabolism in a porcine model of pediatric in-hospital cardiac arrest.
- Karolina Pytlak: Mitochondrial defect in human bronchial epithelial cells lacking the BKCa channel.
- Linsey Stiles: Mitochondrial Respirometry and ATP Hydrolysis Measurements in Previously Frozen Tissue Samples.
- 2023-Jul-29 Saturday
- 08:30 Session B1. Fatty acid oxidation
- Session chairs: Tal Yardeni and Anthony Molina
- 08:30 – 08:55 Adam Chicco: Delta-6 desaturase inhibition reverses aberrant cardiolipin remodeling and mitochondrial dysfunction in the obese mouse heart.
- 08:55 – 09:10 Cesare Granata: Novel mitochondrial respiration protocols reveal organ-specific reliance on ketone body metabolism in mice.
- 09:10 – 09:25 Markus Keller: Exploring the influence of the lipid environment on mitochondrial membrane structure and function.
- 09:25 – 09:40 Yvonne Wohlfarter: The Janus-faced nature of HSD10 in cardiolipin biosynthesis and mitochondrial function.
- 09:40 – 09:55 Luke Whitcomb: Polyunsaturated fatty acid metabolism contributes to age-related impairment of cardiac mitochondrial calcium tolerance.
- 09:55 – 10:10 Luiza Cardoso: Electron transfer from beta-oxidation and TCA cycle and impact of OXPHOS coupling on NADH and coenzyme Q redox states.
- 10:10 Coffee/tea break
- 10:30 Session B2. Type 2 Diabetes
- Session chairs: Sarah Piel and Markus Keller
- 10:30 – 10:55 Christopher Axelrod: Skeletal muscle mitochondrial dynamics in obesity and type 2 diabetes.
- 10:55 – 11:20 Pablo Garcia-Roves: Remission of obesity and insulin resistance. Is that enough?
- 11:20 – 11:35 Pau Gama-Perez: Impact of obesity on white adipose tissue plasticity: addressing differential depot-specific responses.
- 11:35 – 11:50 Dominik Pesta: Respiratory capacity of skeletal muscle and peripheral blood mononuclear cells of male and female individuals with type 2 diabetes.
- 11:50 – 12:05 Lubos Sobotka: Macronutrients energy metabolism and obesity.
- 12:05 - 15:30 Walk & Talk
- 15:30 Session B3. Respiratory complexes
- Session chairs: Tatyana Court and Atan Gross
- 15:30 – 15:55 Orian Shirihai: Inhibition of ATP synthase hydrolytic activity restores cellular energy homeostasis in conditions of impaired respiration.
- 15:55 – 16:10 Maria Jose Saucedo-Rodriguez: Effect of succinate dehydrogenase deficiency on mitochondrial function.
- 16:10 Coffee/tea break
- 16:30 Session B4. Diagnostic approaches
- Session chairs: Alejandra Romero and Lubos Sobotka
- 16:30 – 16:55 Alexander Karabatsiakis: Combined metabolite and lipid fingerprinting of blood serum reveals biomarker candidates of altered mitochondrial bioenergetics in peripheral blood mononuclear cells of female patients with depression.
- 16:55 – 17:20 Dominique-Marie Votion: Serum acylcarnitines profile for diagnosis, prognosis and monitoring therapeutic intervention in equine atypical myopathy.
- 17:20 – 17:35 Ksenija Vujacic-Mirski: Bioenergetics health index and parameters of mitochondrial respiration in relatively healthy individuals. Insight in mitochondrial respiration for diagnosis and future targeted treatments.
- 17:35 – 17: 50 Alba Timon-Gomez: Substrate-uncoupler-inhibitor titration protocol for analyzing carbohydrate and fatty acid metabolism.
- 17:50 – 18:00 Conclusions
- 18:00 – 19:00 MiPs General Assembly
- 19:00 Dinner
- 20:30-21:30 Social evening. Award ceremony.
- 2023-Jul-29 Saturday
- 2023-Jul-30 Sunday Departure
- 09:00 Bus departure
- 2023-Jul-30 Sunday Departure
Oral presentations
| Title | |
|---|---|
| Votion 2023 MiP2023 |  |
| Alan 2023 MiP2023 |  |
| Karabatsiakis 2023 MiP2023 |  |
| Gross 2023 MiP2023 |  |
| Axelrod 2023 MiP2023 |  |
| Kayser 2023 MiP2023 |  |
| Brunetta 2023 MiP2023 |  |
| Cardoso 2023 MiP2023 |  |
| Chicco 2023 MiP2023 |  |
| Gnaiger 2023 MiP2023 |  |
| Gama Perez 2023 MiP2023 |  |
| Garcia-Roves 2023 MiP2023 |  |
| Holloway 2023 MiP2023 |  |
| Granata 2023 MiP2023 |  |
| Guerrier 2023 MiP2023 |  |
| Hand 2023 MiP2023 |  |
| Keller 2023 MiP2023 |  |
| Vujacic-Mirski 2023 MiP2023 |  |
| Larsen 2023 MiP2023 |  |
| Sobotka 2023 MiP2023 |  |
| Mahapatra 2023 MiP2023 |  |
| Molina 2023 MiP2023 |  |
| Owesny 2023 MiP2023 |  |
| Pesta 2023 MiP2023 |  |
| Petrick 2023 MiP2023 |  |
| Sadler 2023 MiP2023 |  |
| Saucedo-Rodriguez 2023 MiP2023 |  |
| Schoenfeld 2023 MiP2023 |  |
| Shirihai 2023 MiP2023 |  |
| Stankova 2023 MiP2023 |  |
| Yardeni 2023 MiP2023 |  |
| Timon-Gomez 2023 MiP2023 |  |
| Whitcomb 2023 MiP2023 |  |
| Wohlfarter 2023 MiP2023 |  |
| Zouhar 2023 MiP2023 |  |
| Valencia 2023 MiP2023 |  |
Poster presentations
| Title | |
|---|---|
| Kolonics 2023 MiP2023 |  |
| Piel 2023 MiP2023 |  |
| Pytlak 2023 MiP2023 | |
| Stiles 2023 MiP2023 | |
| Barkova 2023 MiP203 | |
MiPsociety General Assembly 2023
- The MiPsociety is an international organization, based in Austria and operating world-wide and has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.
- Membership is open to all researchers -» MiPmembership
- Candidates for the election of the Executive MiPcommittee are listed here: MiPcommittee_2023 election candidates
- The MiPs General Assembly will take place during the MiPconference 2023. All MiPmembers have a vote. All MiP223participants are invited to join.
Social event
- The 'Trachtengruppe Umhausen' (translated: Folk group Umhausen) will perform traditional Tyrolean dance at its best.
Invited speakers
Axelrod Christopher L, Pennington Biomedical Research Center, US
Chicco Adam J, Colorado State University, US
Garcia-Roves Pablo Miguel, University of Barcelona and Bellvitge Biomedical Research Institute, ES
Gnaiger Erich, Oroboros Instruments, AT
Gross Atan, Weizmann Institute, IL
Holloway Graham P, University of Guelph, CA
Karabatsiakis Alexander, University of Innsbruck, AT
Kayser Bengt, Université de Lausanne, CH
Larsen Steen, University of Copenhagen, DK
Molina Anthony JA, University of California San Diego, California, US
Pesta Dominik, Institute of Aerospace Medicine, German Aerospace Center, DE
Schoenfeld Peter, former University of Magdeburg, DE
Shirihai Orian, University of California, Los Angeles, US
Votion Dominique-Marie, University of Liège, BE
Yardeni Tal, Sheba Medical Center, Ramat Gan, IL
Zouhar Petr, Institute of Physiology CAS, CZ
Participants
Last update 2023-07-17
Alan Lukas, Czech Academy of Sciences, CZ
Axelrod Christopher L, Pennington Biomedical Research Center, US
Barkova Daria, Biomedical Research Center Slovak Academy of Sciences, SK
Brunetta Henver Simionato, University of Campinas, BR
Canellas da Silva Maria Clara, University of Maryland College Park, US
Cardoso Luiza HD, Oroboros Instruments, AT
Chicco Adam J, Colorado State University, US
Court Sebastien, University of Innsbruck, AT
Court Tatyana, Masaryk University, CZ
Gama Perez Pau, University of Barcelona, ES
Garcia-Roves Pablo Miguel, University of Barcelona and Bellvitge Biomedical Research Institute, ES
Gnaiger Erich, Oroboros Instruments, AT
Granata Cesare, German Diabetes Center (DDZ), DE
Gross Atan, Weizmann Institute, IL
Guerrier Lisa, Université Clermont Auvergne, FR
Hand Steven C, Louisiana State University, US
Handler Alyssa, Stealth Biotherapeutics, US
Holloway Graham P, University of Guelph, CA
Karabatsiakis Alexander, University of Innsbruck, AT
Kayser Bengt, Université de Lausanne, CH
Keller Markus A, Medical University of Innsbruck , AT
Kollberg Gittan, Sahlgrenska University Hospital, SE
Kolonics Attila, University of Physical Education, HU
Laner Verena, Oroboros Instruments, AT
Larsen Steen, University of Copenhagen, DK
Molina Anthony JA, University of California San Diego, California, US
Othonicar Murilo F, UNESP- São Paulo State University, BR
Owesny Patricia, German Institut of Human Nutrition Potsdam-Rehbrücke (DIfE), DE
Pena Gabriel, University of Maryland College Park, US
Pesta Dominik, Institute of Aerospace Medicine, German Aerospace Center, DE
Petrick Heather L, University of Guelph, CA
Phang Howard J, University of California San Diego, US
Piel Sarah, University Hospital Düsseldorf, DE
Pytlak Karolina, Polish Academy of Sciences, PL
Romero Martinez Alejandra, VASCage GmbH, AT
Sadler Daniel, University of Arkansas for Medical Sciences, US
Saucedo-Rodriguez Maria Jose, Charles University, CZ
Schoenfeld Peter, former University of Magdeburg, DE
Shbiro Liat, Sheba Medical Center, IL
Shirihai Orian, University of California, Los Angeles, US
Sobotka Lubos, Charles University, CZ
Stanic Sara, Institute of Physiology of the Czech Academy of Sciences, CZ
Stankova Pavla, Charles University, CZ
Stiles Linsey, University of California, Los Angeles, US
Timon-Gomez Alba, Oroboros Instruments, AT
Valencia Ana P, University of Washington, US
van der Stelt Inge, Wageningen University, NL
Votion Dominique-Marie, University of Liège, BE
Vujacic-Mirski Ksenija, GANZIMMUN Diagnostics GmbH, DE
Weinberger Klaus M, Health Hub Tirol GmbH, AT
Whitcomb Luke A, Colorado State University, US
Wohlfarter Yvonne, Medical University of Innsbruck, AT
Yardeni Tal, Sheba Medical Center, Ramat Gan, IL
Zouhar Petr, Institute of Physiology CAS, CZ
General information
- Local organizers
Gnaiger Erich, Chair MiPsociety, Oroboros Instruments, AT
Laner Verena, General Secretary MiPsociety, Oroboros Instruments, AT
Timon-Gomez Alba, Oroboros Instruments, AT
- International committee
- Axelrod Christopher L, Pennington Biomedical Research Center, US
- Chicco Adam J, Colorado State University, US
- Garcia-Roves Pablo Miguel, University of Barcelona and Bellvitge Biomedical Research Institute, ES
- Gross Atan, Weizmann Institute, IL
- Holloway Graham P, University of Guelph, CA
- Kopecky Jan, Institute of Physiology of the Czech Academy of Sciences, CZ
- Larsen Steen, University of Copenhagen, DK
- Pesta Dominik, Institute of Aerospace Medicine, German Aerospace Center, DE
- Roden Michael, Heinrich Heine University and German Diabetes Center, Düsseldorf, DE
- Shirihai Orian, University of California, Los Angeles, US
- Weigert Cora, University of Tübingen, DE
- Yardeni Tal, Sheba Medical Center, Ramat Gan, IL
- International committee
- Abstracts accepted until event is fully booked.
- Submissions of original contributions on mitObesity and Healthy Aging for the MiP2023 conference are welcome.
- Format: Abstracts up to 250 words with DOI of collected abstracts, which may be extended to full BEC articles.
- Travel info
- To guarantee a smooth transport from Innsbruck to Obergurgl, please arrange your arrival time in Innsbruck according to our travel info below.
- When and how to travel? » Click here for travel info
- To guarantee a smooth transport from Innsbruck to Obergurgl, please arrange your arrival time in Innsbruck according to our travel info below.
- Travel info
- Student travel award
- What? Up to 350 EUR to cover travel costs to attend MiPschool or MiP2023.
- Who is eligible to apply? Undergrad and graduate students who have registered for either or both events.
- How? Apply by registering for a 2023 MiPevent, submitting an abstract and sending a short application letter to [email protected]. Applications without registrations will not be considered.
- When? Registrations, abstracts and application letters must be received by July 9th. Students selected to receive the award will be notified by July 14th.
- Student travel award
Listed under MitoGlobal Events.
Labels:
ORO, 2023, MiP, MitoGlobal, O2k-Network Award Previous
