US VA Richmond Iyer S

From Bioblast


US VA Richmond Iyer S

Oroboros O2k-Network

O2k-Network Lab
Shilpa Iyer

Center for the Study of Biological Complexity

Life Sciences Program

Power-O2k: US VA Richmond Virginia Commonwealth Univ

Address Office number 3139, Harris Hall,

Virginia Commonwealth University, 23284

City Richmond
State/Prov Virginia (VA)
Country USA
Team previous Bennett James P, Iyer Shilpa, Rao Raj R, Surampudi Vasudha
Status O2k 2012-2016; present: US AR Fayetteville Iyer S
Oroboros Events MitoEAGLE 2017 CZ, MiPschool 2017, MiP2014, Bioblast 2012, IOC77, IOC72, IOC54
Topics Mitochondrial diseases, Stem Cells, Respiration


Thomas 2016 Neurodegeneration Therapeutics2016Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41.
Iyer 2012 Hum Gene Ther2012Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr (2012) Mitochondrial gene therapy improves respiration, biogenesis and transcription in G11778A Leber’s hereditary optic neuropathy and T8993G Leigh’s syndrome cells. Hum Gene Ther 23:647-57.
Thomas 2011 Mitochondrion2011Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr (2011) Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18.
Borland 2009 Biochim Biophys Acta2009Borland MK, Mohanakumar KP, Rubinstein JD, Keeney PM, Xie J, Capaldi R, Dunham LD, Trimmer PA, Bennett JP Jr (2009) Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues. Biochim Biophys Acta 792: 68-74.
Iyer 2009 Mitochondrion2009Iyer S, Thomas R, Portell F, Dunham L, Quigley C, Bennett JP (2009) Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression. Mitochondrion 9:196-203.
Keeney 2009 Hum Gene Ther2009Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP (2009) Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907.
Keeney 2009 Exp Neurol2009Keeney PM, Dunham LD, Quigley CK, Morton SL, Bergquist KE, Bennett JP (2009) Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships. Exp Neurol 220:374-82.
Iyer 2008 Nature Precedings2008Iyer S, Thomas R, Portell F, Dunham L, Quigley C, Bennett JP (2008) Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression in G11778A leber’s hereditary optic neuropathy cybrid cells. Nature Precedings: hdl:10101/npre.2008.2084.1


Iyer 2012 Abstract Bioblast2012Iyer S (2012) Gentle Science in the real world of mitochondrial physiology and genetics. Mitochondr Physiol Network 17.12.

Gentle Science

Iyer S, Faris S, Rao R, Jamison R, Maurakis E (2014) Bioenergetics: arts meets gentle science in sickness and in health. In: Laner V, Gnaiger E, eds. Mitochondrial physiology – methods, concepts and biomedical perspectives. MiP2014. Mitochondr Physiol Network 19.13. >>Open Access
Bioenergetics Exhibition - Art meets Gentle Science



Seminar 2015-03-16

Erich Gnaiger


This seminar is a 'guided walk' through the Bioblast website, explaining high-resolution respirometry and the concept of the Oroboros Instruments company.


  • The Bioblast alert is wonderful!! Thank you so much. I am grateful for your support and for promoting gentle science in all you do. Shilpa Iyer (2015-01-15)
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