Difference between revisions of "Talk:MiPschool Obergurgl 2017"
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== Programme development == | |||
:::: ''For the MiPsummer school in Obergurgl the last week of July, I would be delighted to come. I see you have me down for two presentations and you know that I always have a great time at the summer schools and meetings. The Retreat last year kept the tradition of great meetings with unbelievable and fantastic interactions. What can be better. I look forward to the details for travel, etc. My wife asked me how I would be able to turn down your invitation; no way.'' - '''[[Hoppel CL |Charles L Hoppel]]''' | |||
== Abstracts and topics == | == Abstracts and topics == | ||
Revision as of 17:24, 22 July 2017
Programme development
- For the MiPsummer school in Obergurgl the last week of July, I would be delighted to come. I see you have me down for two presentations and you know that I always have a great time at the summer schools and meetings. The Retreat last year kept the tradition of great meetings with unbelievable and fantastic interactions. What can be better. I look forward to the details for travel, etc. My wife asked me how I would be able to turn down your invitation; no way. - Charles L Hoppel
Abstracts and topics
Presentation | Session | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|---|
Afrin 2017 MiPschool Obergurgl | Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism. | B1 Poster | Respiration | Cancer | |||
Amick 2017 MiPschool Obergurgl | Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates. | Oral B2 | Respiration | Other mammals | Nervous system | Alzheimer's | |
Ashcroft 2017 MiPschool Obergurgl | No abstract. | ||||||
Baraldo 2017 MiPschool Obergurgl | Fahd-1 links metabolism and neuronal activity in C. elegans. | D2 Oral | Caenorhabditis elegans | Aging;senescence Neurodegenerative | |||
Bekebrede 2017 MiPschool Obergurgl | No abstract. | ||||||
Bento 2017 MiPschool Obergurgl | Isolation of human urine-derived stem cells for mitochondrial function profile assessment. | D1 | |||||
Bernardino 2017 MiPschool Obergurgl | Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition. | D2 Oral | mt-Biogenesis;mt-density mtDNA;mt-genetics | Human | Genital | ||
Bezuidenhout 2017 MiPschool Obergurgl | No abstract. | ||||||
Brown 2017 MiPschool Obergurgl | Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain. | B1 Oral | Exercise physiology;nutrition;life style | Human | Oxidative stress;RONS | ||
Cizmarova 2017 MiPschool Obergurgl | The scope of cryopreservation in blood cells for functional mitochondrial diagnosis. | E1 Review | Respiration mt-Medicine | Blood cells | Cryopreservation | ||
Collins 2017 MiPschool Obergurgl | The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics. | B2 Oral | Respiration Exercise physiology;nutrition;life style | ||||
Crisostomo 2017 MiPschool Obergurgl | Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential. | B2 Poster | |||||
Di Nolfo 2017 MiPschool Obergurgl | Middle cerebral artery modification in mouse model of Marfan Syndrom and potential role of Nox4. | nDNA;cell genetics Genetic knockout;overexpression | Mouse | Other | |||
Dias 2017 MiPschool Obergurgl | Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells. | D2 Oral | Exercise physiology;nutrition;life style Pharmacology;toxicology | Human | Genital | ||
Distefano 2017 MiPschool Obergurgl | Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects. | B2 Oral | Respiration Exercise physiology;nutrition;life style | Human | Skeletal muscle | Obesity | |
Doerrier 2017 MiPschool C2 | Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles. | C1 Review | Respiration Comparative MiP;environmental MiP | Human Mouse | Heart Nervous system HEK | Cryopreservation | |
Ene 2017 MiPschool Obergurgl | Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo. | B2 Oral | Rat | Nervous system | |||
Ferreira 2017 MiPschool Obergurgl | Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes. | D2 | |||||
Forbes-Hernandez 2017 MiPschool Obergurgl | The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect? | D2 Poster | Respiration mt-Biogenesis;mt-density Pharmacology;toxicology | Human | Liver | ||
Gainutdinov 2017 MiPschool Obergurgl | Different ways of reactive oxygen species (ROS) formation by brain mitochondria. | B1 Poster | |||||
Garcia-Roves 2017 MiPschool Obergurgl | Mitochondrial fitness in skeletal muscle. | E1 Review | Respiration Comparative MiP;environmental MiP Exercise physiology;nutrition;life style mt-Medicine | Skeletal muscle | |||
Garcia-Souza 2017 MiPschool Obergurgl | Assessment of mitochondrial respiratory function in cryopreserved platelets. | C1 Oral | Respiration | Human | Blood cells Platelet | Cryopreservation | |
Gasparrini 2017 MiPschool Obergurgl | Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS. | B1 Poster | Respiration Comparative MiP;environmental MiP Pharmacology;toxicology | Mouse | Macrophage-derived | Oxidative stress;RONS | |
Gerna 2017 MiPschool Obergurgl | No abstract. | ||||||
Ghanim 2017 MiPschool Obergurgl | HAMLET derivatives as a pre-operative therapy in oesophageal cancer. | Pharmacology;toxicology | Cancer | ||||
Giampieri 2017 MiPschool Obergurgl | Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality. | B1 Poster | Respiration Exercise physiology;nutrition;life style Pharmacology;toxicology | Fibroblast | Oxidative stress;RONS | ||
Gnaiger 2017 MiPschool A1 | Elemental steps towards understanding mitochondrial core energy metabolism: coupling control. | A1 Review | Respiration | ||||
Gnaiger 2017 MiPschool A4 | Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology. | A1 Review | Respiration | ||||
Gnaiger 2017 MiPschool C1 | Apparent Complex IV excess capacity and biochemical thresholds. | Review C1 | Respiration | ||||
Gnaiger 2017 MiPschool C4 | Respiratory control ratios and control factors | Review C1 | |||||
Hellgren 2017 MiPschool Obergurgl | Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production. | A1 Oral | Respiration | Mouse | Heart | Hypoxia | |
Hoel 2017 MiPschool Obergurgl | A study on mitochondrial stress responses due to OXPHOS inhibition. | B1 | Respiration mtDNA;mt-genetics | Human | Nervous system | ||
Holzknecht 2017 MiPschool Obergurgl | Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook. | Oral D1 | Respiration Genetic knockout;overexpression | Mouse | Heart | ||
Hoppel 2017 MiPschool Obergurgl A | Biochemical coupling efficiency and ATP/O2 ratios. | A1 Review | |||||
Hoppel 2017 MiPschool Obergurgl E1 | The challenges of functional mitochondrial diagnosis. | E1 Review | nDNA;cell genetics mt-Medicine | Skeletal muscle | |||
Iglesias-Gonzalez 2017 MiPschool Obergurgl | Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control. | B1 | |||||
Irving 2017 MiPSchool Obergurgl | No abstract. | ||||||
Isola 2017 MiPschool Obergurgl | Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies? | B2 Oral | Rat | Diabetes | |||
Iyer 2017a MiPschool Obergurgl | A science-based strategy game for understanding mitochondrial bioenergetics. | ||||||
Iyer 2017b MiPschool Obergurgl | Patient-specific stem cell models for mitochondrial diseases. | D1 Oral | mtDNA;mt-genetics | Fibroblast Stem cells | Other | ||
Jansen-Duerr 2017 MiPschool Obergurgl | Role of mitochondria in ageing and regeneration. | E2 Review | mt-Medicine | ||||
Juhasz 2017 MiPschool Obergurgl | Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats. | D1 Oral | Respiration | Rat | Liver | Other | |
Kamel 2017 MiPschool Obergurgl | No abstract. | ||||||
Karavyraki 2017 MiPschool Obergurgl | Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells. | B1 | Respiration | Human | Cancer | ||
Keppner 2017 MiPschool Obergurgl | Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences. | C1 Oral | Respiration | Blood cells | |||
Komlodi 2017 MiPschool Obergurgl | Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production. | A1 Oral | Respiration | Mouse | Nervous system | Oxidative stress;RONS | |
Koopman 2017 MiPschool Obergurgl | Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation | E2 Review | Instruments;methods | Oxidative stress;RONS | |||
Krajcova 2017 MiPschool Obergurgl | Developing a method of assessing mitochondrial functions in homogenates of human heart muscle. | D1 | |||||
Krylova 2017 MiPschool Obergurgl | High-resolution respirometry in diagnostic of mitochondrial complex I deficiency. | B2 Poster | Respiration mtDNA;mt-genetics mt-Medicine | Endothelial;epithelial;mesothelial cell Fibroblast | |||
Lee 2017 MiPschool Obergurgl | The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation | E2 Review | Comparative MiP;environmental MiP mt-Medicine mt-Awareness | Human | Diabetes Obesity | ||
Liebscher 2017 MiPschool Obergurgl | The LAMTOR complex in regulation of fat metabolism. | D2 Oral | Respiration mtDNA;mt-genetics Genetic knockout;overexpression | Mouse | Fat | ||
Markova 2017 MiPschool Obergurgl | Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase. | D1 Oral | Respiration | Rat | Heart | Oxidative stress;RONS | |
McKenna 2017 MiPschool Obergurgl | A systematic review of the use of respirometry in critically ill patients. | D1 Oral | Respiration mt-Medicine Patients | ||||
Meszaros 2017 MiPschool Obergurgl | (Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration. | A1 Oral | Respiration Instruments;methods | Mouse | Liver Nervous system Kidney | ||
Molina 2017 MiPschool Obergurgl | Scope and limitations of functional mitochondrial diagnosis in blood cells. | E1 | mt-Medicine | Blood cells | |||
Moore 2017 MiPschool Obergurgl | The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen. | A1 Review | Respiration | ||||
Moore 2017 MiPschool Obergurgl E1 | Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives. | E1 Review | |||||
Nogueras 2017 MiPschool Obergurgl | Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients. | C1 Oral | Respiration Patients | Blood cells | Neurodegenerative | ||
Nozickova 2017 MiPschool Obergurgl | Sulfite oxidase. | ||||||
Pavlovic 2017 MiPschool Obergurgl | Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria. | B2 | |||||
Petit 2017 MiPschool Obergurgl | Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence. | Oral D1 | Respiration | Human | Endothelial;epithelial;mesothelial cell | Aging;senescence Cancer | |
Porter 2017 MiPschool Obergurgl | Mitochondrial function and dysfunction in cancer. | E2 | Cancer | ||||
Pranger 2017 MiPschool Obergurgl | No abstract. | ||||||
Rao 2017 MiPSchool Obergurgl | Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl | D1 | |||||
Reboredo-Rodriguez 2017 MiPschool Obergurgl | Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line. | D2 Poster | Respiration Pharmacology;toxicology | Human | Liver | ||
Salti 2017 MiPschool Obergurgl | No abstract. | ||||||
Schartner 2017 MiPschool Obergurgl | No abstract. | ||||||
Schoepp 2017 MiPschool Obergurgl | Generation and characterization of human cardiomyocytes obtained from iPSCs derived from patients with Friedreich’s ataxia. | Patients | Human | Heart | Cardiovascular Neurodegenerative | ||
Sharma 2017 MiPschool Obergurgl | Role of ATP-sensitive potassium (KATP) and maxi potassium (BKCa) channels in beta3-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis). | B2 Poster | Bovines | Genital | |||
Shi 2017 MiPschool Obergurgl | No abstract. | ||||||
Siewiera 2017 MiPschool Obergurgl | Blood platelets as bioenergetic markers of brain damage in STZ-diabetes. | C1 Oral | Respiration | Rat | Blood cells Platelet | Diabetes | |
Silkuniene 2017 MiPschool Obergurgl | Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment. | B1 Oral | Human Other mammals Rat | Nervous system Liver Kidney Islet cell;pancreas;thymus Genital Fibroblast | Temperature | Cancer | |
Soares 2017 MiPschool Obergurgl | Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy. | B2 Oral | Human | Obesity | |||
Sobotka 2017 MiPschool Obergurgl | Reference protocols for ROS production measurements. | A1 Oral | Respiration | ||||
Stevens 2017 MiPschool Obergurgl | No abstract. | ||||||
Tanaka 2017 MiPschool Obergurgl | Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation. | E1 Review | Pharmacology;toxicology | Mouse | Nervous system | ||
Varela-Lopez 2017 MiPschool Obergurgl | Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats. | D2 Poster | Respiration Exercise physiology;nutrition;life style Pharmacology;toxicology | Rat | Liver | Aging;senescence | |
Venz 2017 MiPschool Obergurgl | No abstract. | ||||||
Waldauf 2017 MiPschool Obergurgl | Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates. | Oral | |||||
Yuan 2017 MiPschool Obergurgl | Participant MiPschool Obergurgl 2017. |
Tentative programme Version 01
- Session A (morning) Introduction: coupling control in oxidative phosphorylation
- A1. The electron transfer system – mitochondrial pathways from fuel substrates to oxygen.
- A2. Coupling of the phosphorylation system to electron transfer and respiratory coupling control.
- A3. From Einstein's diffusion equation to Mitchell’s chemiosmotic equation: rates and states in the bioenergetics of oxidative phosphorylation.
- A4. Measurement of coupling in intact cells and mitochondrial preparations: biochemical coupling efficiency and ATP/O2 ratios.
- Session A (morning) Introduction: coupling control in oxidative phosphorylation
- Session B (afternoon) Posters and selected abstracts
- B1. Poster session.
- B2: Selected abstracts: measurement of coupling control in intact cells and mitochondrial preparations - open discussion.
- B3. Towards a data base on coupling control in intact cells.
- Session B (afternoon) Posters and selected abstracts
- 2017-07-25
- Session C (morning) Introduction: from experimental design to data analysis
- C1. Respiratory pathway control in mitochondrial preparations.
- C2. Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
- C3. Normalization of respiratory flux and flow.
- C4. Respiratory control ratios and control factors.
- Session C (morning) Introduction: from experimental design to data analysis
- Session D (afternoon) Posters and selected abstracts
- D1. Selected abstracts: applications of SUIT protocols – open discussion.
- D2. SUIT protocols: design and limitations.
- D3. Towards a data base on mitochondrial respiratory control: diagnostic approaches and comparative mitochondrial physiology.
- Session D (afternoon) Posters and selected abstracts
- 2017-07-26
- Session E (morning) Mitochondrial physiology: biomedical applications (possible titles, depending on keynote lecturers/selected abstracts)
- E1. The challenges of functional mitochondrial diagnosis.
- E2. Mitochondrial fitness in skeletal muscle (Pablo Garcia-Roves, University of Barcelona, ES).
- E3. Scope and limitations of functional mitochondrial diagnosis in blood cells.
- E4. Mitochondrial respiratory function and neuromuscular disease.
- E5. Mitochondrial function and dysfunction in cancer (Richard K Porter, Trinity College Dublin, IE).
- E6. Ischemia-reperfusion injury.
- E7. The metabolic syndrome (Hong Kyu Lee, Eulji University College of Medicine, Seoul, KR).
- E8. Mitochondrial function in aging and regeneration (Pidder Jansen-Duerr, University of Innsbruck, AT).
- Session E (morning) Mitochondrial physiology: biomedical applications (possible titles, depending on keynote lecturers/selected abstracts)
- Session F (afternoon) Comparative mitochondrial physiology (possible titles, depending on keynote lecturers/selected abstracts)
- F1. Mitochondrial physiology in cell models versus primary tissue.
- F2. Mitochondrial physiology studies in mouse models.
- F3. Mitochondrial vertrebrate physiology – extreme performers.
- F5. Mitochondrial physiology of and beyond established animal models.
- F6. Mitochondrial physiology in plants and microbes.
- F7. Mitochondrial physiology and evolution.
- Session F (afternoon) Comparative mitochondrial physiology (possible titles, depending on keynote lecturers/selected abstracts)
Preliminary programme MiPschool (Jul 23-27) Version 02
- This MiPschool will focus on basic concepts on mitochondrial respiratory states and applications of substrate-uncoupler-inhibitor titration (SUIT) protocols.
- Mitochondrial respiratory control: MITOEAGLE recommendations 1
- 2017-07-24
- Session A (morning) Introduction: coupling control in oxidative phosphorylation
- A1. The electron transfer system – Q redox regulation and mitochondrial pathways to oxygen (Anthony L Moore, University of Sussex, UK).
- A2. Coupling of the phosphorylation system to electron transfer and respiratory coupling control (Vilma Borutaite, University of Health Sciences, LT).
- A3. From Einstein's diffusion equation to Mitchell’s chemiosmotic equation: rates and states in the bioenergetics of oxidative phosphorylation (Erich Gnaiger, Medical University of Innsbruck, AT).
- A4. Biochemical coupling efficiency and ATP/O2 ratios (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
- Session A (morning) Introduction: coupling control in oxidative phosphorylation
- Session B (afternoon) Posters and selected abstracts
- B1. Poster session.
- B2: Selected abstracts: measurement of coupling control in intact cells and mitochondrial preparations - open discussion.
- B3. Towards a data base on coupling control in intact cells.
- Session B (afternoon) Posters and selected abstracts
- 2017-07-25
- Session C (morning) Introduction: from experimental design to data analysis
- C1. Respiratory pathway control in mitochondrial preparations (Gnaiger Erich, Medical University of Innsbruck, AT).
- C2. Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles (Carolina Doerrier, OROBOROS INSTRUMENTS, AT).
- C3. Normalization of respiratory flux and flow.
- C4. Respiratory control ratios and control factors (Gnaiger Erich, Medical University of Innsbruck, AT).
- Session C (morning) Introduction: from experimental design to data analysis
- Session D (afternoon) Posters and selected abstracts
- D1. Selected abstracts: applications of SUIT protocols – open discussion.
- D2. SUIT protocols: design and limitations.
- D3. Towards a data base on mitochondrial respiratory control: diagnostic approaches and comparative mitochondrial physiology.
- Session D (afternoon) Posters and selected abstracts
- 2017-07-26
- Session E (morning) Comparative mitochondrial physiology (possible titles, depending on keynote lecturers/selected abstracts)
- E1. Mitochondrial physiology and the scope of cryopreservation in blood cells. (Beata Velika, Pavol Jozef Šafárik University in Kosice, SK)
- E2. Mitochondrial physiology studies in mouse models.
- E3. Mitochondrial vertrebrate physiology – extreme performers.
- E4. Mitochondrial physiology of and beyond established animal models.
- E5. Mitochondrial physiology in plants (Anthony L Moore, University of Sussex, UK).
- E6. Mitochondrial physiology and evolution.
- Session E (morning) Comparative mitochondrial physiology (possible titles, depending on keynote lecturers/selected abstracts)
- Session F (afternoon) Mitochondrial physiology: biomedical applications (possible titles, depending on keynote lecturers/selected abstracts)
- F1. The challenges of functional mitochondrial diagnosis (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
- F2. Mitochondrial fitness in skeletal muscle (Pablo Garcia-Roves, University of Barcelona, ES).
- F3. Scope and limitations of functional mitochondrial diagnosis in blood cells. (Anthony Molina,Department of Internal Medicine, US).
- F4. Mitochondrial function and dysfunction: ROS and Ca2+. (Werner Koopman, Radboud University Nijmegen Medical Centre, NL)
- F5. Mitochondrial function and dysfunction in cancer (Richard K Porter, Trinity College Dublin, IE).
- F6. Ischemia-reperfusion injury (Carlos Palmeira, University of Coimbra, PT).
- F7. The metabolic syndrome - dysmitochondrial syndrome and mitochondrial disruptors (Hong Kyu Lee, Eulji University College of Medicine, Seoul, KR).
- F8. Mitochondrial function in aging and regeneration (Pidder Jansen-Duerr, University of Innsbruck, AT).
- Session F (afternoon) Mitochondrial physiology: biomedical applications (possible titles, depending on keynote lecturers/selected abstracts)
- Session G (evening) MITOEAGLE Early Career Investigators forum