O2k-Publications: Oxygraph-2k

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O2k-Publications: Oxygraph-2k

O2k-Publications in the MiPMap

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 YearReferenceOrganismTissue;cell
MiPNet28.10 POS-service2025-01-04
O2k-Manual
Service of the polarographic oxygen sensor POS.
Korandova 2025 Anal Biochem2025Korandová Z, Pecina P, Pecinová A, Koňaříková E, Tesařová M, Houštěk J, Hansíková H, Ptáčková H, Zeman J, Honzík T, Mráček T (2025) Cryopreserved PBMCs can be used for the analysis of mitochondrial respiration and serve as a diagnostic tool for mitochondrial diseases. Anal Biochem 698:115745. https://doi.org/10.1016/j.ab.2024.115745HumanBlood cells
Sato 2025 Brain Res2025Sato N, Kusano T, Nagata K, Okamoto K (2025) A non-purine inhibitor of xanthine oxidoreductase mitigates adenosine triphosphate degradation under hypoxic conditions in mouse brain. Brain Res [Epub ahead of print]. https://doi.org/10.1016/j.brainres.2025.149444
Zhang 2025 Ecotoxicol Environ Saf2025Zhang Y, Lv J, Sun X, Zhang Y, Shao M, Shi B, Zhang Y, Gu J, Zhao C, Liu F (2025) Toxicity of antimony in housefly after whole-life-cycle exposure: Changes in growth, development, redox homeostasis, mitochondrial function, and fecundity. Ecotoxicol Environ Saf 289:117656. https://doi.org/10.1016/j.ecoenv.2024.117656Hexapods
Larrea 2025 Nat Commun2025Larrea D, Tamucci KA, Kabra K, Velasco KR, Yun TD, Pera M, Montesinos J, Agrawal RR, Paradas C, Smerdon JW, Lowry ER, Stepanova A, Yoval-Sanchez B, Galkin A, Wichterle H, Area-Gomez E (2025) Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS). Nat Commun 16:379. https://doi.org/10.1038/s41467-024-51578-1MouseNervous system
Cardoso 2025 Biochim Biophys Acta Mol Basis Dis2025Cardoso LHD, Cecatto C, Ozola M, Korzh S, Zvejniece L, Gukalova B, Doerrier C, Dambrova M, Makrecka-Kuka M, Gnaiger E, Liepinsh E (2025) Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models. Biochim Biophys Acta Mol Basis Dis 1871:167544. https://doi.org/10.1016/j.bbadis.2024.167544Mouse
Rat
Drosophila
Heart
Nervous system
Kidney
Holody 2025 Am J Physiol Heart Circ Physiol2025Holody CD, Woodman AG, Nie C, Liu SN, Young D, Wiedemeyer A, Carpenter R, Noble RMN, Graf D, Dufour A, Lemieux H, Bourque SL (2025) Perinatal iron deficiency alters the cardiac proteome and mitochondrial function in neonatal offspring. Am J Physiol Heart Circ Physiol 328:H101-12. https://doi.org/10.1152/ajpheart.00412.2024RatHeart
MiPNet18.10 Oroboros sole source2024-12-31
Oroboros
Oroboros instrument specifications for high-resolution respirometry and precision OXPHOS analysis.
MiPNet19.14 Hamilton microsyringes2024-12-10
Oroboros Manual
Hamilton microsyringes: titrations and maintenance.
MiPNet21.14 Reference sample HRR2024-12-06
Oroboros_Procedures
Development of a reference sample for high-resolution respirometry.
HumanHEK
MiPNet28.08 Oroboros O2k Series J Manual2024-02-20
O2k-Manual
Oroboros O2k-Series J Manual.
Xu 2024 Sci Adv2024Xu G, Quan S, Schell J, Gao Y, Varmazyad M, Sreenivas P, Cruz D, Jiang H, Pan M, Han X, Palavicini JP, Zhao P, Sun X, Marchant ED, Rasmussen BB, Li G, Katsumura S, Morita M, Munkácsy E, Horikoshi N, Chocron ES, Gius D (2024) Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease. Sci Adv 10:eadj5942. https://doi.org/10.1126/sciadv.adj5942MouseLiver
Wang 2024 Commun Biol2024Wang Y, Fu X, Zeng L, Hu Y, Gao R, Xian S, Liao S, Huang J, Yang Y, Liu J, Jin H, Klaunig J, Lu Y, Zhou S (2024) Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury. Commun Biol 7:621. https://doi.org/10.1038/s42003-024-06243-0MouseLiver
Navarro 2024 Exp Gerontol2024Navarro CDC, Francisco A, Costa EFD, Dalla Costa AP, Sartori MR, Bizerra PFV, Salgado AR, Figueira TR, Vercesi AE, Castilho RF (2024) Aging-dependent mitochondrial bioenergetic impairment in the skeletal muscle of NNT-deficient mice. Exp Gerontol 193:112465. https://doi.org/10.1016/j.exger.2024.112465MouseSkeletal muscle
Liepinsh 2024 Br J Pharmacol2024Liepinsh E, Zvejniece L, Clemensson L, Ozola M, Vavers E, Cirule H, Korzh S, Skuja S, Groma V, Briviba M, Grinberga S, Liu W, Olszewski P, Gentreau M, Fredriksson R, Dambrova M, Schiöth HB (2024) Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver. Br J Pharmacol [Epub ahead of print]. https://doi.org/10.1111/bph.16363MouseLiver
Noerregaard 2024 J Physiol2024Noerregaard LB, Hansen CC, Wickham KA, Moeller S, Olsen K, Ehlers T, Bangsbo J, Hellsten Y (2024) Exercise training alters skeletal muscle microvascular endothelial cell properties in recent postmenopausal females. J Physiol 602:3449-68. https://doi.org/10.1113/jp286269HumanSkeletal muscle
Endothelial;epithelial;mesothelial cell
Leo 2024 MitoFit2024Leo E, Rychtarova L, Garcia-Souza LF, Åsander Frostner E, Elmér E, Gnaiger E (2024) High-resolution respirometry in a small-volume chamber. MitoFit Preprints 2024.4.v2. https://doi.org/10.26124/mitofit:2024-0004.v2 - Accepted on 2024-10-27 as Manuscript JoVE67442R2 for publication in JoVEHuman
Mouse
Heart
Nervous system
Blood cells
HUVEC
Platelet
Thome 2024 JCI Insight2024Thome T, Vugman NA, Stone LE, Wimberly K, Scali ST, Ryan TE (2024) A tryptophan-derived uremic metabolite-Ahr-Pdk4 axis governs skeletal muscle mitochondrial energetics in chronic kidney disease. JCI Insight [Epub ahead of print]. https://doi.org/10.1172/jci.insight.178372Human
Mouse
Skeletal muscle
Chmelova 2024 Int J Parasitol2024Chmelová Ľ, Kraeva N, Saura A, Krayzel A, Vieira CS, Ferreira TN, Soares RP, Bučková B, Galan A, Horáková E, Vojtková B, Sádlová J, Malysheva MN, Butenko A, Prokopchuk G, Frolov AO, Lukeš J, Horváth A, Škodová-Sveráková I, Feder D, Yu Kostygov A, Yurchenko V (2024) Intricate balance of dually-localized catalase modulates infectivity of Leptomonas seymouri (Kinetoplastea: Trypanosomatidae). Int J Parasitol [Epub ahead of print]. https://doi.org/10.1016/j.ijpara.2024.04.007Protists
Evinova 2024 J Bioenerg Biomembr2024Evinova A, Baranovicova E, Hajduchova D, Dibdiakova K, Baranova I, Racay P, Strnadel J, Pecova R, Halasova E, Pokusa M (2024) The impact of ATP-sensitive potassium channel modulation on mitochondria in a Parkinson's disease model using SH-SY5Y cells depends on their differentiation state. J Bioenerg Biomembr [Epub ahead of print]. https://doi.org/10.1007/s10863-024-10018-xHumanNeuroblastoma
Lhuissier 2024 iScience2024Lhuissier C, Desquiret-Dumas V, Girona A, Alban J, Faure J, Cassereau J, Codron P, Lenaers G, Baris OR, Gueguen N, Chevrollier A (2024) Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission. iScience 27:109808. https://doi.org/10.1016/j.isci.2024.109808MouseFibroblast
Sorby-Adams 2024 Redox Biol2024Sorby-Adams A, Prime TA, Miljkovic JL, Prag HA, Krieg T, Murphy MP (2024) A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding. Redox Biol 72:103161. https://doi.org/10.1016/j.redox.2024.103161RatHeart
Buescher 2024 Acta Physiol (Oxf)2024Buescher FM, Schmitz MT, Frett T, Kramme J, de Boni L, Elmenhorst EM, Mulder E, Moestl S, Heusser K, Frings-Meuthen P, Jordan J, Rittweger J, Pesta D (2024) Effects of 30 days bed rest and exercise countermeasures on PBMC bioenergetics. Acta Physiol (Oxf) 240(3):e14102. https://doi.org/10.1111/apha.14102HumanBlood cells
Garcia-Poyatos 2024 Dev Cell2024García-Poyatos C, Arora P, Calvo E, Marques IJ, Kirschke N, Galardi-Castilla M, Lembke C, Meer M, Fernández-Montes P, Ernst A, Haberthür D, Hlushchuk R, Vázquez J, Vermathen P, Enríquez JA, Mercader N (2024) Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization. Dev Cell [Epub ahead of print]. https://doi.org/10.1016/j.devcel.2024.04.012Zebrafish
Fishes
Skeletal muscle
Jacovetti 2024 Mol Metab2024Jacovetti C, Donnelly C, Menoud V, Suleiman M, Cosentino C, Sobel J, Wu K, Bouzakri K, Marchetti P, Guay C, Kayser B, Regazzi R (2024) The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion. Mol Metab 84:101955. https://doi.org/10.1016/j.molmet.2024.101955RatIslet cell;pancreas;thymus
Hu 2024 Ecotoxicol Environ Saf2024Hu R, Fan W, Li S, Zhang G, Zang L, Qin L, Li R, Chen R, Zhang L, Gu W, Zhang Y, Rajagopalan S, Sun Q, Liu C (2024) PM2.5-induced cellular senescence drives brown adipose tissue impairment in middle-aged mice. Ecotoxicol Environ Saf 278:116423. https://doi.org/10.1016/j.ecoenv.2024.116423MouseFat
Jiang 2024 Nat Metab2024Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG (2024) Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nat Metab [Epub ahead of print]. https://doi.org/10.1038/s42255-024-01038-3MouseLiver
Hardorp 2024 Bachelor-Thesis2024Hardorp RA (2024) Oxygen consumption and production measured by high-resolution respirometry in leaf preparations from Robinia pseudoacacia. Bachelor-Thesis 47 pp.Plants
Kuerec 2024 Ageing Res Rev2024Kuerec AH, Lim XK, Khoo AL, Sandalova E, Guan L, Feng L, Maier AB (2024) Targeting aging with urolithin A in humans: A systematic review. Ageing Res Rev 100:102406. https://doi.org/10.1016/j.arr.2024.102406
Samodelov 2024 Sci Rep2024Samodelov SL, Gai Z, De Luca F, Haldimann K, Hobbie SN, Müller D, Kullak-Ublick GA, Visentin M (2024) L-carnitine co-administration prevents colistin-induced mitochondrial permeability transition and reduces the risk of acute kidney injury in mice. Sci Rep 14:16444. https://doi.org/10.1038/s41598-024-67171-xMouseKidney
Ogilvie 2024 Am J Pathol2024Ogilvie LM, Delfinis LJ, Coyle-Asbil B, Vudatha V, Alshamali R, Garlisi B, Pereira M, Matuszewska K, Garibotti MC, Gandhi S, Brunt KR, Wood GA, Trevino JG, Perry CGR, Petrik J, Simpson JA (2024) Cardiac atrophy, dysfunction, and metabolic impairments: a cancer-induced cardiomyopathy phenotype. Am J Pathol [Epub ahead of print]. https://doi.org/10.1016/j.ajpath.2024.06.008
Zhao 2024 J Adv Res2024Zhao Y, Lu Z, Zhang H, Wang L, Sun F, Li Q, Cao T, Wang B, Ma H, You M, Zhou Q, Wei X, Li L, Liao Y, Yan Z, Liu D, Gao P, Zhu Z (2024) Sodium-glucose exchanger 2 inhibitor canagliflozin promotes mitochondrial metabolism and alleviates salt-induced cardiac hypertrophy via preserving SIRT3 expression. J Adv Res [Epub ahead of print]. https://doi.org/10.1016/j.jare.2024.04.030MouseHeart
Greenwood 2024 PLoS One2024Greenwood JC, Morgan RW, Abella BS, Shofer FS, Baker WB, Lewis A, Ko TS, Forti RM, Yodh AG, Kao SH, Shin SS, Kilbaugh TJ, Jang DH (2024) Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol. PLoS One 19:e0302653. https://doi.org/10.1371/journal.pone.0302653PigNervous system
Alvarez-Sanchez 2024 Cell Mol Life Sci2024Álvarez-Sánchez A, Grinat J, Doria-Borrell P, Mellado-López M, Pedrera-Alcócer É, Malenchini M, Meseguer S, Hemberger M, Pérez-García V (2024) The GPI-anchor biosynthesis pathway is critical for syncytiotrophoblast differentiation and placental development. Cell Mol Life Sci 81:246. https://doi.org/10.1007/s00018-024-05284-2MouseStem cells
Wilburn 2024 Sci Rep2024Wilburn D, Miserlis D, Fletcher E, Papoutsi E, Ismaeel A, Bradley C, Ring A, Wilkinson T, Smith RS, Ferrer L, Haynatzki G, Monteleone P, Banerjee S, Brisbois E, Bohannon WT, Koutakis P (2024) Skeletal muscle desmin alterations following revascularization in peripheral artery disease claudicants. Sci Rep 14:12609. https://doi.org/10.1038/s41598-024-63626-3HumanSkeletal muscle
Morishita 2024 Biol Pharm Bull2024Morishita R, Onishi A, Oya M, Karashima H, Mori M, Kawatani Y, Kamei N, Takeda-Morishita M (2024) Effect of orally ingested water containing H2-filled ultrafine bubbles (UFBs) on ethanol-induced oxidative stress in rats. Biol Pharm Bull 47:1106-12. https://doi.org/10.1248/bpb.b24-00034RatLiver
Brunner 2024 Life Sci Alliance2024Brunner S, Höring M, Liebisch G, Schweizer S, Scheiber J, Giansanti P, Hidrobo M, Hermeling S, Oeckl J, Prudente de Mello N, Perocchi F, Seeliger C, Strohmeyer A, Klingenspor M, Plagge J, Küster B, Burkhardt R, Janssen KP, Ecker J (2024) Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity. Life Sci Alliance 7:e202402828. https://doi.org/10.26508/lsa.202402828MouseFat
Westerlund 2024 Heliyon2024Westerlund E, Marelsson SE, Karlsson M, Sjövall F, Chamkha I, Åsander Frostner E, Lundgren J, Fellman V, Eklund EA, Steding-Ehrenborg K, Darin N, Paul G, Hansson MJ, Ehinger JK, Elmér E (2024) Correlation of mitochondrial respiration in platelets, peripheral blood mononuclear cells and muscle fibers. Heliyon 10:e26745. https://doi.org/10.1016/j.heliyon.2024.e26745HumanSkeletal muscle
Blood cells
Platelet
Lorito 2024 EMBO Mol Med2024Lorito N, Subbiani A, Smiriglia A, Bacci M, Bonechi F, Tronci L, Romano E, Corrado A, Longo DL, Iozzo M, Ippolito L, Comito G, Giannoni E, Meattini I, Avgustinova A, Chiarugi P, Bachi A, Morandi A (2024) FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer. EMBO Mol Med [Epub ahead of print]. https://doi.org/10.1038/s44321-024-00090-6HumanEndothelial;epithelial;mesothelial cell
Wang 2024 Adv Sci (Weinh)2024Wang H, Stevens T, Lu J, Roberts A, Van't Land C, Muzumdar R, Gong Z, Vockley J, Prochownik EV (2024) Body-wide inactivation of the Myc-like Mlx transcription factor network accelerates aging and increases the lifetime cancer incidence. Adv Sci (Weinh) [Epub ahead of print]. https://doi.org/10.1002/advs.202401593MouseFat
Skeletal muscle
Liver
Chi 2024 BMC Biol2024Chi WY, Lee GH, Tang MJ, Chen BH, Lin WL, Fu TF (2024) Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation. BMC Biol 22:146. https://doi.org/10.1186/s12915-024-01946-6HumanLiver
Endothelial;epithelial;mesothelial cell
Song 2024 Commun Biol2024Song A, Zhao N, Hilpert DC, Perry C, Baur JA, Wallace DC, Schaefer PM (2024) Visualizing subcellular changes in the NAD(H) pool size versus redox state using fluorescence lifetime imaging microscopy of NADH. Commun Biol 7:428. https://doi.org/10.1038/s42003-024-06123-7HumanHEK
Dulac 2024 J Physiol2024Dulac M, Hajj-Boutros G, Sonjak V, Faust A, Hussain SNA, Chevalier S, Dionne IJ, Morais JA, Gouspillou G (2024) A multimodal exercise countermeasure prevents the negative impact of head-down tilt bed rest on muscle volume and mitochondrial health in older adults. J Physiol [Epub ahead of print]. https://doi.org/10.1113/jp285897HumanSkeletal muscle
Li 2024 Cell Res2024Li M, Wang Y, Wei X, Cai WF, Wu J, Zhu M, Wang Y, Liu YH, Xiong J, Qu Q, Chen Y, Tian X, Yao L, Xie R, Li X, Chen S, Huang X, Zhang C, Xie C, Wu Y, Xu Z, Zhang B, Jiang B, Wang ZC, Li Q, Li G, Lin SY, Yu L, Piao HL, Deng X, Han J, Zhang CS, Lin SC (2024) AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine. Cell Res [Epub ahead of print]. https://doi.org/10.1038/s41422-024-00985-6MouseSkeletal muscle
Tabara 2024 Cell2024Tábara LC, Burr SP, Frison M, Chowdhury SR, Paupe V, Nie Y, Johnson M, Villar-Azpillaga J, Viegas F, Segawa M, Anand H, Petkevicius K, Chinnery PF, Prudent J (2024) MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels. Cell 187:3619-37.e27. https://doi.org/10.1016/j.cell.2024.05.017Human
Fitzgerald 2024 J Cachexia Sarcopenia Muscle2024Fitzgerald LF, Lackey J, Moussa A, Shah SV, Castellanos AM, Khan S, Schonk M, Thome T, Salyers ZR, Jakkidi N, Kim K, Yang Q, Hepple RT, Ryan TE (2024) Chronic aryl hydrocarbon receptor activity impairs muscle mitochondrial function with tobacco smoking. J Cachexia Sarcopenia Muscle 15:646-59. https://doi.org/10.1002/jcsm.13439MouseSkeletal muscle
Cefis 2024 Acta Physiol (Oxf)2024Cefis M, Dargegen M, Marcangeli V, Taherkhani S, Dulac M, Leduc-Gaudet JP, Mayaki D, Hussain SNA, Gouspillou G (2024) MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission. Acta Physiol (Oxf) 240:e14119. https://doi.org/10.1111/apha.14119MouseSkeletal muscle
Donnelly 2024 Redox Biol2024Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion A-C, Matera A, Tavernari D, Campiche O, Paolicelli RC, Zanou N, Kayser B, Gnaiger E, Place N (2024) Functional hypoxia reduces mitochondrial calcium uptake. Redox Biol 71:103037. https://doi.org/10.1016/j.redox.2024.103037Human
Mouse
Heart
Skeletal muscle
Meszaros 2024 Transpl Int2024Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. Transpl Int 37:12380. https://doi.org/10.3389/ti.2024.12380HumanLiver
Xiao 2024 Sci Adv2024Xiao L, Yin Y, Sun Z, Liu J, Jia Y, Yang L, Mao Y, Peng S, Xie Z, Fang L, Li J, Xie X, Gan Z (2024) AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise. Sci Adv 10:eadj2752. https://doi.org/10.1126/sciadv.adj2752MouseSkeletal muscle
Hu 2024 Front Endocrinol (Lausanne)2024Hu Y, Fang B, Tian X, Wang H, Tian X, Yu F, Li T, Yang Z, Shi R (2024) Passive exercise is an effective alternative to HRT for restoring OVX induced mitochondrial dysfunction in skeletal muscle. Front Endocrinol (Lausanne) 15:1356312. https://doi.org/10.3389/fendo.2024.1356312MouseSkeletal muscle
Opperdoes 2024 BMC Genomics2024Opperdoes FR, Záhonová K, Škodová-Sveráková I, Bučková B, Chmelová Ľ, Lukeš J, Yurchenko V (2024) In silico prediction of the metabolism of Blastocrithidia nonstop, a trypanosomatid with non-canonical genetic code. BMC Genomics 25:184. https://doi.org/10.1186/s12864-024-10094-8Protists
Al-Sabri 2024 Sci Rep2024Al-Sabri MH, Ammar N, Korzh S, Alsehli AM, Hosseini K, Fredriksson R, Mwinyi J, Williams MJ, Boukhatmi H, Schiöth HB (2024) Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes. Sci Rep 14:3338. https://doi.org/10.1038/s41598-024-53446-wDrosophilaSkeletal muscle
Fehsenfeld 2024 Comp Biochem Physiol A Mol Integr Physiol2024Fehsenfeld S, Yoon GR, Quijada-Rodriguez AR, Kandachi-Toujas H, Calosi P, Breton S, Weihrauch D (2024) Short-term exposure to high pCO2 leads to decreased branchial cytochrome C oxidase activity in the presence of octopamine in a decapod. https://doi.org/10.1016/j.cbpa.2024.111603
Romagnolo 2024 Acta Neuropathol2024Romagnolo A, Dematteis G, Scheper M, Luinenburg MJ, Mühlebner A, Van Hecke W, Manfredi M, De Giorgis V, Reano S, Filigheddu N, Bortolotto V, Tapella L, Anink JJ, François L, Dedeurwaerdere S, Mills JD, Genazzani AA, Lim D, Aronica E (2024) Astroglial calcium signaling and homeostasis in tuberous sclerosis complex. Acta Neuropathol 147:48. https://doi.org/10.1007/s00401-024-02711-3HumanNervous system
Qiao 2024 J Sport Health Sci2024Qiao YS, Blackwell TL, Cawthon PM, Coen PM, Cummings SR, Distefano G, Farsijani S, Forman DE, Goodpaster BH, Kritchevsky SB, Mau T, Toledo FGS, Newman AB, Glynn NW (2024) Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics: The Study of Muscle, Mobility and Aging (SOMMA). https://doi.org/10.1016/j.jshs.2024.02.001HumanSkeletal muscle
Pegoraro 2024 Adv Drug Deliv Rev2024Pegoraro C, Domingo I, Conejos-Sánchez I, Vicent MJ (2024) Unlocking the mitochondria for nanomedicine-based treatments: overcoming biological barriers, improving designs, and selecting verification techniques. Adv Drug Deliv Rev 207:115195. https://doi.org/10.1016/j.addr.2024.115195
Lin 2024 Apoptosis2024Lin HY, Liang CJ, Yang MY, Chen PL, Wang TM, Chen YH, Shih YH, Liu W, Chiu CC, Chiang CK, Lin CS, Lin HC (2024) Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury. https://doi.org/10.1007/s10495-023-01897-3HumanKidney
Nastasi 2024 Int J Mol Sci2024Nastasi MR, Borisov VB, Forte E (2024) Membrane-bound redox enzyme cytochrome bd-I promotes carbon monoxide-resistant Escherichia coli growth and respiration. https://doi.org/10.3390/ijms25021277
Ravasz 2024 Sci Rep2024Ravasz D, Bui D, Nazarian S, Pallag G, Karnok N, Roberts J, Marzullo BP, Tennant DA, Greenwood B, Kitayev A, Hill C, Komlódi T, Doerrier C, Cunatova K, Fernandez-Vizarra E, Gnaiger E, Kiebish Michael A, Raska A, Kolev K, Czumbel B, Narain NR, Seyfried TN, Chinopoulos C (2024) Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia. Sci Rep 14:1729. https://doi.org/10.1038/s41598-024-51365-4MouseHeart
Liver
Balmaceda 2024 Biochim Biophys Acta Mol Basis Dis2024Balmaceda V, Komlodi T, Szibor M, Gnaiger E, Moore AL, Fernandez-Vizarra E, Viscomi C (2024) The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease. Biochim Biophys Acta Mol Basis Dis 1870:167033. https://doi.org/10.1016/j.bbadis.2024.167033MouseNervous system
Liver
Patil 2024 J Exp Biol2024Patil YN, Gnaiger E, Landry AP, Leno ZJ, Hand SC (2024) OXPHOS capacity is diminished and the phosphorylation system inhibited during diapause in an extremophile, embryos of Artemia franciscana. J Exp Biol 227:jeb.245828. https://doi.org/10.1242/jeb.245828Artemia
Shi 2024 Clin Sci (Lond)2024Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z (2024) Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning. Clin Sci (Lond) 138:371-85. https://doi.org/10.1042/cs20230973MouseFibroblast
Davis 2024 BEC2024Davis MS, Barrett MR, Bayly WM, Bolinger A (2024) Effect of selected fluorophores on equine skeletal muscle mitochondrial respiration. Bioenerg Commun 2024.2. https://doi.org/10.26124/bec:2024-0002HorseSkeletal muscle
Ciccone 2024 J Exp Biol2024Ciccone C, Kante F, Folkow LP, Hazlerigg DG, West AC, Wood SH (2024) Circadian coupling of mitochondria in a deep-diving mammal. J Exp Biol 227:jeb24699. https://doi.org/10.1242/jeb.246990Other mammalsFibroblast
Mahapatra 2024 J Gerontol A Biol Sci Med Sci2024Mahapatra G, Gao Z, Bateman JR 3rd, Lockhart SN, Bergstrom J, Piloso JE, Craft S, Molina AJA (2024) Peripheral blood cells from older adults exhibit sex-associated differences in mitochondrial function. J Gerontol A Biol Sci Med Sci [Epub ahead of print]. https://doi.org/10.1093/gerona/glae098HumanBlood cells
Holwerda 2024 J Cachexia Sarcopenia Muscle2024Holwerda AM, Dirks ML, Barbeau PA, Goessens J, Gijsen A, van Loon LJC, Holloway GP (2024) Mitochondrial bioenergetics are not associated with myofibrillar protein synthesis rates. J Cachexia Sarcopenia Muscle 15:1811-22. https://doi.org/10.1002/jcsm.13532Human
Mouse
Skeletal muscle
Queiroz 2024 Ecotoxicol Environ Saf2024Queiroz MIC, Lazaro CM, Dos Santos LMB, Rentz T, Virgilio-da-Silva JV, Moraes-Vieira PMM, Cunha FAS, Santos JCC, Vercesi AE, Leite ACR, Oliveira HCF (2024) In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice. Ecotoxicol Environ Saf 275:116254. https://doi.org/10.1016/j.ecoenv.2024.116254MouseLiver
Meldau 2024 Mol Genet Metab Rep2024Meldau S, Ackermann S, Riordan G, van der Watt GF, Spencer C, Raga S, Khan K, Blackhurst DM, van der Westhuizen FH (2024) A novel mitochondrial DNA variant in MT-ND6: m.14430A>C p.(Trp82Gly) identified in a patient with Leigh syndrome and complex I deficiency. Mol Genet Metab Rep 39:101078. https://doi.org/10.1016/j.ymgmr.2024.101078HumanFibroblast
Natsui 2024 Physiol Rep2024Natsui H, Watanabe M, Yokota T, Tsuneta S, Fumoto Y, Handa H, Shouji M, Koya J, Nishino K, Tatsuta D, Koizumi T, Kadosaka T, Nakao M, Koya T, Temma T, Ito YM, Kanako HC, Hatanaka Y, Yasushige S, Wakasa S, Miura S, Masuda T, Nishioka N, Naraoka S, Ochi K, Kudo T, Ishikawa T, Anzai T (2024) Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery. Physiol Rep 12:e15957. https://doi.org/10.14814/phy2.15957HumanFat
Hunter-Manseau 2024 Insect Sci2024Hunter-Manseau F, Cormier SB, Strang R, Pichaud N (2024) Fasting as a precursor to high-fat diet enhances mitochondrial resilience in Drosophila melanogaster. Insect Sci [Epub ahead of print]. https://doi.org/10.1111/1744-7917.13355Drosophila
Vera-Vives 2024 Plant Physiol Biochem2024Vera-Vives AM, Michelberger T, Morosinotto T, Perin G (2024) Assessment of photosynthetic activity in dense microalgae cultures using oxygen production. Plant Physiol Biochem 208:108510. https://doi.org/10.1016/j.plaphy.2024.108510Algae
Dong 2024 Nat Commun2024Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H (2024) Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease. https://doi.org/10.1038/s41467-023-44057-6MouseLiver
Visker 2024 Exp Physiol2024Visker JR, Leszczynski EC, Wellette-Hunsucker AG, McPeek AC, Quinn MA, Kim SH, Bazil JN, Ferguson DP (2024) Postnatal growth restriction alters myocardial mitochondrial energetics in mice. https://doi.org/10.1113/ep091304MouseHeart
Tsouka 2024 Commun Med (Lond)2024Tsouka S, Kumar P, Seubnooch P, Freiburghaus K, St-Pierre M, Dufour JF, Masoodi M (2024) Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human. Commun Med (Lond) 4:39. https://doi.org/10.1038/s43856-024-00465-3MouseLiver
Abegg 2024 Toxicol Lett2024Abegg VF, Panajatovic MV, Mancuso RV, Allard JA, Duthaler U, Odermatt A, Krähenbühl S, Bouitbir J (2024) Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells. https://doi.org/10.1016/j.toxlet.2024.01.008HumanLiver
Kim 2024 J Exerc Rehabil2024Kim TW, Park SS, Kim SH, Kim MK, Shin MS, Kim SH (2024) Exercise before pregnancy exerts protective effect on prenatal stress-induced impairment of memory, neurogenesis, and mitochondrial function in offspring. J Exerc Rehabil 20:2-10. https://doi.org/10.12965/jer.2448068.034MouseNervous system
Taylor 2024 Pilot Feasibility Stud2024Taylor MK, Burns JM, Choi IY, Herda TJ, Lee P, Smith AN, Sullivan DK, Swerdlow RH, Wilkins HM (2024) Protocol for a single-arm, pilot trial of creatine monohydrate supplementation in patients with Alzheimer's disease. Pilot Feasibility Stud 10:42. https://doi.org/10.1186/s40814-024-01469-5HumanLymphocyte
Platelet
Torcasio 2024 J Transl Med2024Torcasio R, Gallo Cantafio ME, Veneziano C, De Marco C, Ganino L, Valentino I, Occhiuzzi MA, Perrotta ID, Mancuso T, Conforti F, Rizzuti B, Martino EA, Gentile M, Neri A, Viglietto G, Grande F, Amodio N (2024) Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity. J Transl Med 22:208. https://doi.org/10.1186/s12967-024-05013-0HumanBlood cells
Cela 2024 Int J Mol Sci2024Cela O, Scrima R, Pacelli C, Rosiello M, Piccoli C, Capitanio N (2024) Autonomous oscillatory mitochondrial respiratory activity: results of a systematic analysis show heterogeneity in different in vitro-synchronized cancer cells. Int J Mol Sci 25:7797. https://doi.org/10.3390/ijms25147797
Rydzanicz 2024 EMBO Mol Med2024Rydzanicz M, Kuzniewska B, Magnowska M, Wójtowicz T, Stawikowska A, Hojka A, Borsuk E, Meyza K, Gewartowska O, Gruchota J, Miłek J, Wardaszka P, Chojnicka I, Kondrakiewicz L, Dymkowska D, Puścian A, Knapska E, Dziembowski A, Płoski R, Dziembowska M (2024) Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males. EMBO Mol Med [Epub ahead of print]. https://doi.org/10.1038/s44321-024-00147-6MouseNervous system
Li 2024 Biomed Pharmacother2024Li D, Yuan X, Ma J, Lu T, Zhang J, Liu H, Zhang G, Wang Y, Liu X, Xie Q, Zhou L, Xu M (2024) Morusin, a novel inhibitor of ACLY, induces mitochondrial apoptosis in hepatocellular carcinoma cells through ROS-mediated mitophagy. Biomed Pharmacother 180:117510. https://doi.org/10.1016/j.biopha.2024.117510HumanLiver
Robledo-Cadena 2024 PLoS One2024Robledo-Cadena DX, Pacheco-Velázquez SC, Vargas-Navarro JL, Padilla-Flores JA, López-Marure R, Pérez-Torres I, Kaambre T, Moreno-Sánchez R, Rodríguez-Enríquez S (2024) Synergistic celecoxib and dimethyl-celecoxib combinations block cervix cancer growth through multiple mechanisms. PLoS One 19:e0308233. https://doi.org/10.1371/journal.pone.0308233HumanOther cell lines
HeLa
Shabalina 2024 Biochim Biophys Acta Bioenerg2024Shabalina IG, Jiménez B, Sousa-Filho CPB, Cannon B, Nedergaard J (2024) In isolated brown adipose tissue mitochondria UCP1 is not essential for nor involved in the uncoupling effects of the classical uncouplers FCCP and DNP. Biochim Biophys Acta Bioenerg [Epub ahead of print]. https://doi.org/10.1016/j.bbabio.2024.149516MouseFat
Doan 2024 Nat Cardiovasc Res2024Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA (2024) Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics. Nat Cardiovasc Res [Epub ahead of print]. https://doi.org/10.1038/s44161-024-00542-9MouseHeart
Somers 2024 Biomed Pharmacother2024Somers T, Siddiqi S, Janssen MCM, Morshuis WJ, Maas RGC, Buikema JW, van den Broek PHH, Schirris TJJ, Russel FGM (2024) Effect of statins on mitochondrial function and contractile force in human skeletal and cardiac muscle. Biomed Pharmacother 180:117492. https://doi.org/10.1016/j.biopha.2024.117492HumanHeart
Skeletal muscle
Shirakawa 2024 Sci Rep2024Shirakawa R, Nakajima T, Yoshimura A, Kawahara Y, Orito C, Yamane M, Handa H, Takada S, Furihata T, Fukushima A, Ishimori N, Nakagawa M, Yokota I, Sabe H, Hashino S, Kinugawa S, Yokota T (2024) Author Correction: Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults. Sci Rep 14:6786. https://doi.org/10.1038/s41598-024-57171-2. Erratum for: Sci Rep. 2023 13:5203. https://doi.org/10.1038/s41598-023-32549-wHumanBlood cells
Fuchs 2024 J Physiol2024Fuchs CJ, Betz MW, Petrick HL, Weber J, Senden JM, Hendriks FK, Bels JLM, van Loon LJC, Snijders T (2024) Repeated passive heat treatment increases muscle tissue capillarization, but does not affect postprandial muscle protein synthesis rates in healthy older adults. J Physiol [Epub ahead of print]. https://doi.org/10.1113/jp286986Skeletal muscle
Rizo-Roca 2024 Sci Transl Med2024Rizo-Roca D, Guimarães DSPSF, Pendergrast LA, Di Leo N, Chibalin AV, Maqdasy S, Rydén M, Näslund E, Zierath JR, Krook A (2024) Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes. Sci Transl Med 16:eado3022. https://doi.org/10.1126/scitranslmed.ado3022MouseSkeletal muscle
Song 2024 PLoS One2024Song J, Ei Ayadi A, Rontoyanni VG, Wolf SE (2024) Mild burn amplifies the locomotive depression in demyelinated mice without muscle pathophysiological changes. PLoS One 19:e0308908. https://doi.org/10.1371/journal.pone.0308908MouseSkeletal muscle
Gotvaldova 2024 Cancer Metab2024Gotvaldová K, Špačková J, Novotný J, Baslarová K, Ježek P, Rossmeislová L, Gojda J, Smolková K (2024) BCAA metabolism in pancreatic cancer affects lipid balance by regulating fatty acid import into mitochondria. Cancer Metab 12:10. https://doi.org/10.1186/s40170-024-00335-5HumanOther cell lines
Carvalho 2024 Lab Anim (NY)2024Carvalho LRRA, Shimari M, Boeder AM, Zhuge Z, Cai M, Leijding C, Gastaldello S, Kleschyov AL, Schiffer TA, Guimarães DD, Picozzi G, Lund LH, Fellström B, Weitzberg E, Lundberg JO, Hagberg CE, Pironti G, Andersson DC, Carlström M (2024) A novel model of cardiovascular-kidney-metabolic syndrome combining unilateral nephrectomy and high-salt-sugar-fat diet in mice. Lab Anim (NY) 53:336-46. https://doi.org/10.1038/s41684-024-01457-5MouseHeart
Kidney
Gaviraghi 2024 Mol Microbiol2024Gaviraghi A, Barletta ABF, Silva TLAE, Oliveira MP, Sorgine MHF, Oliveira MF (2024) Activation of innate immunity selectively compromises mitochondrial complex I, proline oxidation, and flight activity in the major arbovirus vector Aedes aegypti. Mol Microbiol [Epub ahead of print]. https://doi.org/10.1111/mmi.15269HexapodsSkeletal muscle
Mennuni 2024 Sci Adv2024Mennuni M, Wilkie SE, Michon P, Alsina D, Filograna R, Lindberg M, Sanin DE, Rosenberger F, Schaaf A, Larsson E, Pearce EL, Larsson NG (2024) High mitochondrial DNA levels accelerate lung adenocarcinoma progression. Sci Adv 10:eadp3481. https://doi.org/10.1126/sciadv.adp3481MouseLung;gill
Artman 2024 J Equine Vet Sci2024Artman JL, Wesolowski LT, Semanchik PL, Isles JK, Norton SA, White-Springer SH (2024) Local and systemic responses to repeated gluteal muscle microbiopsies in mature sedentary horses. J Equine Vet Sci 136:105070. https://doi.org/10.1016/j.jevs.2024.105070HorseSkeletal muscle
Ward 2024 Mol Biol Rep2024Ward AS, Hall CN, Tree MO, Kohtz DS (2024) Spheroid architecture strongly enhances miR-221/222 expression and promotes oxidative phosphorylation in an ovarian cancer cell line through a mechanism that includes restriction of miR-9 expression. Mol Biol Rep 51:275. https://doi.org/10.1007/s11033-023-09168-9
Miklovicova 2024 Biochim Biophys Acta Mol Basis Dis2024Miklovicova S, Volpini L, Sanovec O, Monaco F, Vanova KH, Novak J, Boukalova S, Zobalova R, Klezl P, Tomasetti M, Bobek V, Fiala V, Vcelak J, Santarelli L, Bielcikova Z, Komrskova K, Kolostova K, Pacak K, Dvorakova S, Neuzil J (2024) Mitochondrial respiratory complex II is altered in renal carcinoma. Biochim Biophys Acta Mol Basis Dis 1871:167556. https://doi.org/10.1016/j.bbadis.2024.167556HumanKidney
Kristensen 2024 Nat Metab2024Kristensen JM, Kjøbsted R, Larsen TJ, Carl CS, Hingst JR, Onslev J, Birk JB, Thorup A, Steenberg DE, Knudsen JR, Henriksen NS, Needham EJ, Halling JF, Gudiksen A, Rundsten CF, Hanghøj KE, Stinson SE, Hoier B, Hansen CC, Jensen TE, Hellsten Y, Pilegaard H, Grarup N, Olesen J, Humphrey SJ, James DE, Pedersen ML, Richter EA, Hansen T, Jørgensen ME, Wojtaszewski JFP (2024) Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise. Nat Metab [Epub ahead of print]. https://doi.org/10.1038/s42255-024-01153-1HumanSkeletal muscle
Peng 2024 Eur J Sport Sci2024Peng SC, Lin YT, Hsu CC, Fu TC, Wang JS (2024) Effects of concentric and eccentric exercise regimens on bioenergetic efficiency of lymphocytes in sedentary males. Eur J Sport Sci [Epub ahead of print]. https://doi.org/10.1002/ejsc.12221HumanBlood cells
Longo 2024 Mol Cell2024Longo M, Bishnu A, Risiglione P, Montava-Garriga L, Cuenco J, Sakamoto K, MacKintosh C, Ganley IG (2024) Opposing roles for AMPK in regulating distinct mitophagy pathways. Mol Cell [Epub ahead of print]. https://doi.org/10.1016/j.molcel.2024.10.025
Allerton 2024 Sci Rep2024Allerton TD, Stampley JE, Li Z, Yu X, Quiariate H, Doiron JE, White G, Wigger Z, Gartia MR, Lefer DJ, Soto P, Irving BA (2024) Nitric oxide donors rescue metabolic and mitochondrial dysfunction in obese Alzheimer's model. Sci Rep 14:26118. https://doi.org/10.1038/s41598-024-75870-8MouseNervous system
Ehinger 2024 NPJ Aging2024Ehinger JK, Westerlund E, Åsander Frostner E, Karlsson M, Paul G, Sjövall F, Elmér E (2024) Mitochondrial function in peripheral blood cells across the human lifespan. NPJ Aging 10:10. https://doi.org/10.1038/s41514-023-00130-4HumanBlood cells
Malik 2024 Nat Metab2024Malik MY, Guo F, Asif-Malik A, Eftychidis V, Barkas N, Eliseeva E, Timm KN, Wolska A, Bergin D, Zonta B, Ratz-Wirsching V, von Hörsten S, Walton ME, Magill PJ, Nerlov C, Minichiello L (2024) Impaired striatal glutathione-ascorbate metabolism induces transient dopamine increase and motor dysfunction. Nat Metab [Epub ahead of print]. https://doi.org/10.1038/s42255-024-01155-zMouseNervous system
Lanzillotta 2024 Free Radic Biol Med2024Lanzillotta S, Esteve D, Lanzillotta C, Tramutola A, Lloret A, Forte E, Pesce V, Picca A, Di Domenico F, Perluigi M, Barone E (2024) Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain. Free Radic Biol Med [Epub ahead of print]. https://doi.org/10.1016/j.freeradbiomed.2024.11.043MouseNervous system
Agca 2024 J Cachexia Sarcopenia Muscle2024Agca S, Domaniku-Waraich A, Bilgic SN, Sucuoglu M, Dag M, Dogan SA, Kir S (2024) Tumour-induced alterations in single-nucleus transcriptome of atrophying muscles indicate enhanced protein degradation and reduced oxidative metabolism. J Cachexia Sarcopenia Muscle 15:1898-1914. https://doi.org/10.1002/jcsm.13540MouseSkeletal muscle
Davis 20242024Davis MS, Bayly WM, Hansen CM, Barrett MR, Blake CA (2024) Effects of hyperthermia and acidosis on mitochondrial oxidative phosphorylation. J Appl Physiol 325:R725-34. https://doi.org/10.1152/ajpregu.00177.2023HorseSkeletal muscle
Baglivo 2024 BEC2024Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2024) Stability of mitochondrial respiration medium used in high-resolution respirometry with living and permeabilized cells. Bioenerg Commun 2024.8. https://doi.org/10.26124/bec.2024-0008HumanHEK
Dos Santos 2024 J Alzheimers Dis2024Dos Santos JR, Catalão CHR, Vulczak A, Azzolini AECS, Alberici LC (2024) Voluntary wheel running decreases amyloidogenic pathway and rescues cognition and mitochondrial energy metabolism in middle-aged female 3xTg-AD mouse model of Alzheimer's disease. J Alzheimers Dis 102:424-36. https://doi.org/10.1177/13872877241289388MouseNervous system
Bahire 2024 Antioxidants (Basel)2024Bahire KL, Maļuhins R, Bello F, Upīte J, Makarovs A, Jansone B (2024) Long-term region-specific mitochondrial functionality changes in both cerebral hemispheres after fMCAo model of ischemic stroke. Antioxidants (Basel) 13:416. https://doi.org/10.3390/antiox13040416MouseNervous system
Sartori 2024 Pediatr Res2024Sartori LF, Tsemberis E, Hernandez T, Luchette K, Zhang D, Farooqi S, Bush J, McCann JC, Balamuth F, Weiss SL (2024) Distinct mitochondrial respiration profiles in pediatric patients with febrile illness versus sepsis. Pediatr Res [Epub ahead of print]. https://doi.org/10.1038/s41390-024-03420-zHumanBlood cells
Kolb 2024 Biochemistry2024Kolb AJ, Corridon P, Ullah M, Pfaffenberger ZJ, Xu WM, Winfree S, Sandoval RH, Hato T, Witzmann FA, Mohallem R, Franco J, Aryal UK, Atkinson SJ, Basile DP, Bacallao RL (2024) Sulfotransferase 1C2 increases mitochondrial respiration by converting mitochondrial membrane cholesterol to cholesterol sulfate. Biochemistry [Epub ahead of print]. https://doi.org/10.1021/acs.biochem.3c00344RatKidney
Huang 2024 Cell Mol Life Sci2024Huang Y, Yang Y, Chen X, Zeng S, Chen Y, Wang H, Lv X, Hu X, Teng L (2024) Downregulation of malic enzyme 3 facilitates progression of gastric carcinoma via regulating intracellular oxidative stress and hypoxia-inducible factor-1α stabilization. Cell Mol Life Sci 81:375. https://doi.org/10.1007/s00018-024-05388-9
Kahl 2024 J Hepatol2024Kahl S, Straßburger K, Pacini G, Trinks N, Pafili K, Mastrototaro L, Dewidar B, Sarabhai T, Trenkamp S, Esposito I, Schlensak M, Granderath FA, Roden M (2024) Dysglycemia and liver lipid content determine the relationship of insulin resistance with hepatic OXPHOS capacity in obesity. J Hepatol [Epub ahead of print]. https://doi.org/10.1016/j.jhep.2024.08.012HumanLiver
Magri 2024 Cell Death Discov2024Magrì A, Lipari CLR, Caccamo A, Battiato G, Conti Nibali S, De Pinto V, Guarino F, Messina A (2024) AAV-mediated upregulation of VDAC1 rescues the mitochondrial respiration and sirtuins expression in a SOD1 mouse model of inherited ALS. Cell Death Discov 10:178. https://doi.org/10.1038/s41420-024-01949-wMouseNervous system
Caulat 2024 mBio2024Caulat LC, Lotoux A, Martins MC, Kint N, Anjou C, Teixeira M, Folgosa F, Morvan C, Martin-Verstraete I (2024) Physiological role and complex regulation of O2-reducing enzymes in the obligate anaerobe Clostridioides difficile. mBio [Epub ahead of print]. https://doi.org/10.1128/mbio.01591-24Eubacteria
Pfleger 2024 Biochim Biophys Acta Bioenerg2024Pfleger A, Arc E, Grings M, Gnaiger E, Roach T (2024) Flavodiiron proteins prevent the Mehler reaction in Chlamydomonas reinhardtii. Biochim Biophys Acta Bioenerg 1865:149497. https://doi.org/10.1016/j.bbabio.2024.149497Algae
Benayada 2024 J Funct Foods2024Benayada L, Gubitosa F, Fraternale D, Carloni S, Cerioni L, Matacchione G, Olivieri F, Potenza L, De Bellis R, Chiarantini L, Roselli C, Valentini L, Gobbi P, Balduini W, Pappagallo N, Ventura N, Kass GEN, Colomba M, Albertini MC (2024) In vitro anti-inflammatory activity of Malus × domestica var. Mela Rosa Marchigiana pulp callus extract contrasting high glucose conditions. J Funct Foods 121:106420. https://doi.org/10.1016/j.jff.2024.106420HumanOther cell lines
Doerrier 2024 Free Radic Biol Med2024Doerrier C, Gama-Perez P, Pesta D, Distefano G, Soendergaard SD, Maise Chroeis K, Gonzalez-Franquesa A, Goodpaster BH, Prats C, Sales-Pardo M, Guimera R, Coen PM, Gnaiger E, Larsen S, Garcia-Roves PM (2024) Harmonization of experimental procedures to assess mitochondrial respiration in human permeabilized skeletal muscle fibers. Free Radic Biol Med 223:384-97. https://doi.org/10.1016/j.freeradbiomed.2024.07.039HumanSkeletal muscle
Wang 2024 J Biomed Sci2024Wang V, Tseng KY, Kuo TT, Huang EY, Lan KL, Chen ZR, Ma KH, Greig NH, Jung J, Choi HI, Olson L, Hoffer BJ, Chen YH (2024) Attenuating mitochondrial dysfunction and morphological disruption with PT320 delays dopamine degeneration in MitoPark mice. J Biomed Sci 31:38. https://doi.org/10.1186/s12929-024-01025-6MouseNervous system
Au 2024 Life Sci Alliance2024Au WH, Miller-Fleming L, Sanchez-Martinez A, Lee JA, Twyning MJ, Prag HA, Raik L, Allen SP, Shaw PJ, Ferraiuolo L, Mortiboys H, Whitworth AJ (2024) Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models. Life Sci Alliance 7:e202402853. https://doi.org/10.26508/lsa.202402853Drosophila
Timon-Gomez 2024 MitoFit2024Timón-Gómez A, Doerrier C, Sumbalová Z, Garcia-Souza LF, Baglivo E, Cardoso LHD, Gnaiger E (2024) Analysis of mitochondrial respiratory pathway and coupling control by substrate-uncoupler-inhibitor titration reference protocols. MitoFit Preprints 2024.8. https://doi.org/10.26124/mitofit:2024-0008Human
Mouse
HEK
Heart
Nervous system
Liver
Blood cells
Tagliafico 2024 Aging Cell2024Tagliafico L, Da Costa RT, Boccia L, Kavehmoghaddam S, Ramirez B, Tokarska-Schlattner M, Scoma ER, Hambardikar V, Bonfiglio T, Caffa I, Monacelli F, Schlattner U, Betley JN, Nencioni A, Solesio ME (2024) Short-term starvation activates AMPK and restores mitochondrial inorganic polyphosphate, but fails to reverse associated neuronal senescence. Aging Cell [Epub ahead of print]. https://doi.org/10.1111/acel.14289HumanNeuroblastoma
Fernandez-Tocino 2024 Basic Res Cardiol2024Fernández-Tocino M, Pun-Garcia A, Gómez M, Clemente-Moragón A, Oliver E, Villena-Gutierrez R, Trigo-Anca S, Díaz-Guerra A, Sanz-Rosa D, Prados B, Del Campo L, Andrés V, Fuster V, de la Pompa JL, Cádiz L, Ibañez B (2024) β3-Adrenergic receptor overexpression in cardiomyocytes preconditions mitochondria to withstand ischemia-reperfusion injury. Basic Res Cardiol [Epub ahead of print]. https://doi.org/10.1007/s00395-024-01072-yMouseHeart
Zhang 2024 Cell Metab2024Zhang Y, Higgins CB, Tica S, Adams JA, Sun J, Kelly SC, Zong X, Dietzen DJ, Pietka T, Ballentine SJ, Shriver L, Patti G, Cao Y, DeBosch BJ (2024) Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism. Cell Metab [Epub ahead of print]. https://doi.org/10.1016/j.cmet.2024.07.007MouseLiver
Cazares-Preciado 2024 BMJ Open Diabetes Res Care2024Cázares-Preciado JA, López-Arredondo A, Cruz-Cardenas JA, Luévano-Martínez LA, García-Rivas G, Prado-Garcia H, Brunck MEG (2024) Metabolic features of neutrophilic differentiation of HL-60 cells in hyperglycemic environments. BMJ Open Diabetes Res Care 12:e004181. https://doi.org/10.1136/bmjdrc-2024-004181HumanBlood cells
Liu 2024 Cell Death Dis2024Liu JC, Zhao XY, Wu ML, Shi YF, Huang ZP, Fang LP, Zhu C, Peng X, Shi ZL, Lan LJ, Ji WL, Luo L, Feng L, Zhang ZL, Xu DE, Li S, Qin ZH, Sun YY, Schachner M, Ma QH (2024) GPR50 regulates neuronal development as a mitophagy receptor. Cell Death Dis 15:591. https://doi.org/10.1038/s41419-024-06978-yMouseNervous system
Xu 2024 Redox Biol2024Xu K, Saaoud F, Shao Y, Lu Y, Yang Q, Jiang X, Wang H, Yang X (2024) A new paradigm in intracellular immunology: Mitochondria emerging as leading immune organelles. Redox Biol 76:103331. https://doi.org/10.1016/j.redox.2024.103331
Coulson 2024 J Exp Biol2024Coulson SZ, Guglielmo CG, Staples JF (2024) Migration increases mitochondrial oxidative capacity without increasing reactive oxygen species emission in a songbird. J Exp Biol 227:jeb246849. https://doi.org/10.1242/jeb.246849BirdsSkeletal muscle
Jardon 2024 Gut Microbes2024Jardon KM, Goossens GH, Most J, Galazzo G, Venema K, Penders J, Blaak EE (2024) Examination of sex-specific interactions between gut microbiota and host metabolism after 12-week combined polyphenol supplementation in individuals with overweight or obesity. Gut Microbes 16:2392875. https://doi.org/10.1080/19490976.2024.2392875HumanSkeletal muscle
Perry 2024 JCI Insight2024Perry CE, Halawani SM, Mukherjee S, Ngaba LV, Lieu M, Lee WD, Davis JG, Adzika GK, Bebenek AN, Bazianos DD, Chen B, Mercado-Ayon E, Flatley LP, Suryawanshi AP, Ho I, Rabinowitz JD, Serai SD, Biko DM, Tamaroff J, DeDio A, Wade K, Lin KY, Livingston DJ, McCormack SE, Lynch DR, Baur JA (2024) NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia. JCI Insight 9:e177152. https://doi.org/10.1172/jci.insight.177152MouseHeart
Puighermanal 2024 Nat Commun2024Puighermanal E, Luna-Sánchez M, Gella A, van der Walt G, Urpi A, Royo M, Tena-Morraja P, Appiah I, de Donato MH, Menardy F, Bianchi P, Esteve-Codina A, Rodríguez-Pascau L, Vergara C, Gómez-Pallarès M, Marsicano G, Bellocchio L, Martinell M, Sanz E, Jurado S, Soriano FX, Pizcueta P, Quintana A (2024) Cannabidiol ameliorates mitochondrial disease via PPARγ activation in preclinical models. Nat Commun 15:7730. https://doi.org/10.1038/s41467-024-51884-8MouseNervous system
Balnis 2024 Sci Adv2024Balnis J, Tufts A, Jackson EL, Drake LA, Singer DV, Lacomis D, Lee CG, Elias JA, Doles JD, Maher LJ 3rd, Jen A, Coon JJ, Jourd'heuil D, Singer HA, Vincent CE, Jaitovich A (2024) Succinate dehydrogenase-complex II regulates skeletal muscle cellular respiration and contractility but not muscle mass in genetically induced pulmonary emphysema. Sci Adv [Epub ahead of print]. https://doi.org/10.1126/sciadv.ado8549MouseSkeletal muscle
Dong 2024 Orphanet J Rare Dis2024Dong Q, Yin X, Fan S, Zhong S, Yang W, Chen K, Wang Q, Ma X, Mahlatsi RL, Yang Y, Lyu J, Fang H, Wang Y (2024) IARS2 mutations lead to Leigh syndrome with a combined oxidative phosphorylation deficiency. Orphanet J Rare Dis 19:305. https://doi.org/10.1186/s13023-024-03310-xHumanLymphocyte
Li 2024 Sci Rep2024Li J, Zhang S, Li C, Zhang X, Shan Y, Zhang Z, Bo H, Zhang Y (2024) Endurance exercise-induced histone methylation modification involved in skeletal muscle fiber type transition and mitochondrial biogenesis. Sci Rep 14:21154. https://doi.org/10.1038/s41598-024-72088-6RatSkeletal muscle
Lavorato 2024 JCI Insight2024Lavorato M, Iadarola D, Remes C, Kaur P, Broxton C, Mathew ND, Xiao R, Seiler C, Nakamaru-Ogiso E, Anderson VE, Falk MJ (2024) dldhcri3 zebrafish exhibited altered mitochondrial ultrastructure, morphology and dysfunction partially rescued by probucol or thiamine. JCI Insight [Epub ahead of print]. https://doi.org/10.1172/jci.insight.178973Zebrafish
Fishes
Alanova 2024 Acta Physiol (Oxf)2024Alanova P, Alan L, Opletalova B, Bohuslavova R, Abaffy P, Matejkova K, Holzerova K, Benak D, Kaludercic N, Menabo R, Di Lisa F, Ostadal B, Kolar F, Pavlinkova G (2024) HIF-1α limits myocardial infarction by promoting mitophagy in mouse hearts adapted to chronic hypoxia. Acta Physiol (Oxf) [Epub ahead of print]. https://doi.org/10.1111/apha.14202MouseHeart
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MiPNet19.03 Oroboros cleaning and ISS2023-03-14
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MiPNet22.11 O2k-FluoRespirometer manual2023-03-14
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MiPNet28.03 IOC157 Los Angeles US2023-02-14
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MiPNet06.03 POS-calibration-SOP2023-02-06
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Hryc 2023 Nat Commun2023Hryc CF, Mallampalli VKPS, Bovshik EI, Azinas S, Fan G, Serysheva II, Sparagna GC, Baker ML, Mileykovskaya E, Dowhan W (2023) Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex. https://doi.org/10.1038/s41467-023-38441-5Saccharomyces cerevisiae
Szulik 2023 Basic Res Cardiol2023Szulik MW, Valdez S, Walsh M, Davis K, Bia R, Horiuchi E, O'Very S, Laxman AK, Sandaklie-Nicolova L, Eberhardt DR, Durrant JR, Sheikh H, Hickenlooper S, Creed M, Brady C, Miller M, Wang L, Garcia-Llana J, Tracy C, Drakos SG, Funai K, Chaudhuri D, Boudina S, Franklin S (2023) SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation. https://doi.org/10.1007/s00395-023-00991-6MouseHeart
Bellar 2023 Clin Transl Med2023Bellar A, Welch N, Dasarathy J, Attaway A, Musich R, Kumar A, Sekar J, Mishra S, Sandlers Y, Streem D, Nagy LE, Dasarathy S (2023) Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol-associated hepatitis. https://doi.org/10.1002/ctm2.1276HumanBlood cells
Kienzle 2023 BMC Biol2023Kienzle L, Bettinazzi S, Choquette T, Brunet M, Khorami HH, Jacques JF, Moreau M, Roucou X, Landry CR, Angers A, Breton S (2023) A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics. https://doi.org/10.1186/s12915-023-01609-yHumanHEK
HeLa
Pereyra 2023 Am J Physiol Gastrointest Liver Physiol2023Pereyra AS, McLaughlin KL, Buddo KA, Ellis JM (2023) Medium-chain fatty acid oxidation is independent of L-carnitine in liver and kidney but not in heart and skeletal muscle. https://doi.org/10.1152/ajpgi.00105.2023MouseHeart
Skeletal muscle
Liver
Kidney
Oliveira 2023 J Biol Chem2023Oliveira AG, Oliveira LD, Cruz MV, Guimarães DSPSF, Lima TI, BC Santos-Fávero, Luchessi AD, BA Pauletti, Leme AP, Bajgelman MC, Afonso J, Regitano LCA, Carvalho HF, Carneiro EM, Kobarg J, Perissi V, Auwerx J, Silveira LR (2023) Interaction between poly-A binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response. https://doi.org/10.1016/j.jbc.2023.104702
Mills 2023 Nature2023Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA (2023) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. https://doi.org/10.1038/nature25986RatLiver
Clemente 2023 Commun Biol2023Clemente N, Baroni S, Fiorilla S, Tasso F, Reano S, Borsotti C, Ruggiero MR, Alchera E, Corrazzari M, Walker G, Follenzi A, Crich SG, Carini R (2023) Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice. https://doi.org/10.1038/s42003-023-04946-4HumanLiver
Airik 2023 Antioxidants (Basel)2023Airik M, Arbore H, Childs E, Huynh AB, Phua YL, Chen CW, Aird K, Bharathi S, Zhang B, Conlon P, Kmoch S, Kidd K, Bleyer AJ, Vockley J, Goetzman E, Wipf P, Airik R (2023) Mitochondrial ROS triggers KIN pathogenesis in FAN1-deficient kidneys. https://doi.org/10.3390/antiox12040900HumanKidney
Czyzowska 2023 Redox Biol2023Czyżowska A, Brown J, Xu H, Sataranatarajan K, Kinter M, Tyrell VJ, O'Donnell VB, Van Remmen H (2023) Elevated phospholipid hydroperoxide glutathione peroxidase (GPX4) expression modulates oxylipin formation and inhibits age-related skeletal muscle atrophy and weakness. Redox Biol 64:102761. https://doi.org/10.1016/j.redox.2023.102761MouseSkeletal muscle
Gemmink 2023 Mol Metab2023Gemmink A, Daemen S, Wefers J, Hansen J, van Moorsel D, Astuti P, Jorgensen JA, Kornips E, Schaart G, Hoeks J, Schrauwen P, Hesselink MKC (2023) Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity. https://doi.org/10.1016/j.molmet.2023.101727HumanSkeletal muscle
Giovarelli 2023 Mol Med2023Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. https://doi.org/10.1186/s10020-023-00645-2HumanGenital
Cruz-Gregorio 2023 Phytother Res2023Cruz-Gregorio A, Aranda-Rivera AK, Aparicio-Trejo OE, Medina-Campos ON, Sciutto E, Fragoso G, Pedraza-Chaverri J (2023) α-Mangostin induces oxidative damage, mitochondrial dysfunction, and apoptosis in a triple-negative breast cancer model. https://doi.org/10.1002/ptr.7812MouseEndothelial;epithelial;mesothelial cell
Silaidos 2023 Geroscience2023Silaidos CV, Reutzel M, Wachter L, Dieter F, Ludin N, Blum WF, Wudy SA, Matura S, Pilatus U, Hattingen E, Pantel J, Eckert GP (2023) Age-related changes in energy metabolism in peripheral mononuclear blood cells (PBMCs) and the brains of cognitively healthy seniors. https://doi.org/10.1007/s11357-023-00810-9HumanBlood cells
Patitucci 2023 bioRxiv2023Patitucci C, Hernández-Camacho JD, Vimont E, Cokelaer T, Chaze T, Gianetto QG, Matondo M, Gazi A, Nemazanyy I, Stroud DA, Hock DH, Donnarumma E, Wai T (2023) Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis. bioRxiv https://doi.org/10.1101/2023.04.26.538374 .
Hosler 2023 Mitochondrion2023Hosler J, Hoang N, Shirey Edwards K (2023) The cyclic lipopeptide micafungin induces rupture of isolated mitochondria by reprograming the mitochondrial inner membrane anion channel. Mitochondrion 71:50-62. https://doi.org/10.1016/j.mito.2023.05.004RatLiver
Ackerly 2023 Comp Biochem Physiol A Mol Integr Physiol2023Ackerly KL, Negrete B Jr, Dichiera AM, Esbaugh AJ (2023) Hypoxia acclimation improves mitochondrial efficiency in the aerobic swimming muscle of red drum (Sciaenops ocellatus). https://doi.org/10.1016/j.cbpa.2023.111443Fishes
Nollet 2023 Eur Heart J2023Nollet EE, Duursma I, Rozenbaum A, Eggelbusch M, Wüst RCI, Schoonvelde SAC, Michels M, Jansen M, van der Wel NN, Bedi KC, Margulies KB, Nirschl J, Kuster DWD, van der Velden J (2023) Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration. https://doi.org/10.1093/eurheartj/ehad028HumanHeart
Kankuri 2023 Exp Mol Med2023Kankuri E, Finckenberg P, Leinonen J, Tarkia M, Björk S, Purhonen J, Kallijärvi J, Kankainen M, Soliymani R, Lalowski M, Mervaala E (2023) Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity. https://doi.org/10.1038/s12276-023-00967-5MouseHeart
Moellering 2023 Arthritis Res Ther2023Moellering DR, Smith-Johnston K, Kelley C, Sammy MJ, Benedict J, Brock G, Johnson J, Baskin KK, Jarjour WN, Belury MA, Reiser PJ, Nagareddy PR, Hanaoka BY (2023) Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study. https://doi.org/10.1186/s13075-023-03065-zHumanSkeletal muscle
Stampley 2023 Physiol Rep2023Stampley JE, Cho E, Wang H, Theall B, Johannsen NM, Spielmann G, Irving BA (2023) Impact of maximal exercise on immune cell mobilization and bioenergetics. https://doi.org/10.14814/phy2.15753HumanBlood cells
Peixoto 2023 J Physiol Biochem2023Peixoto ÁS, Moreno MF, Castro É, Perandini LA, Belchior T, Oliveira TE, Vieira TS, Gilio GR, Tomazelli CA, Leonardi BF, Ortiz-Silva M, Silva Junior LP, Moretti EH, Steiner AA, Festuccia WT (2023) Hepatocellular carcinoma induced by hepatocyte Pten deletion reduces BAT UCP-1 and thermogenic capacity in mice, despite increasing serum FGF-21 and iWAT browning. https://doi.org/10.1007/s13105-023-00970-4MouseLiver
Fat
Diaz 2023 Front Mol Biosci2023Diaz EC, Adams SH, Weber JL, Cotter M, Børsheim E (2023) Elevated LDL-C, high blood pressure, and low peak V˙O2 associate with platelet mitochondria function in children-The Arkansas Active Kids Study. Front Mol Biosci 10:1136975. https://doi.org/10.3389/fmolb.2023.1136975HumanBlood cells
Platelet
Pharaoh 2023 Geroscience2023Pharaoh G, Kamat V, Kannan S, Stuppard RS, Whitson J, Martín-Pérez M, Qian WJ, MacCoss MJ, Villén J, Rabinovitch P, Campbell MD, Sweet IR, Marcinek DJ (2023) The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT). Geroscience 45:3529-48. https://doi.org/10.1007/s11357-023-00861-yMouseSkeletal muscle
Zhang 2023 J Cachexia Sarcopenia Muscle2023Zhang S, Yan H, Ding J, Wang R, Feng Y, Zhang X, Kong X, Gong H, Lu X, Ma A, Hua Y, Liu H, Guo J, Gao H, Zhou Z, Wang R, Chen P, Liu T, Kong X (2023) Skeletal muscle-specific DJ-1 ablation-induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy. https://doi.org/10.1002/jcsm.13290MouseSkeletal muscle
Frangos 2023 J Biol Chem2023Frangos SM, DesOrmeaux GJ, Holloway GP (2023) Acidosis attenuates CPT-I supported bioenergetics as a potential mechanism limiting lipid oxidation. https://doi.org/10.1016/j.jbc.2023.105079MouseSkeletal muscle
Steffen 2023 J Exp Biol2023Steffen JBM, Sokolov EP, Bock C, Sokolova IM (2023) Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, Crassostrea gigas. J Exp Biol 226:jeb246164. https://doi.org/10.1242/jeb.246164MolluscsLung;gill
Dewidar 2023 EBioMedicine2023Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. https://doi.org/10.1016/j.ebiom.2023.104714MouseSkeletal muscle
Liver
Fisher-Wellman 2023 Cancers (Basel)2023Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC (2023) Simultaneous inhibition of ceramide hydrolysis and glycosylation synergizes to corrupt mitochondrial respiration and signal caspase driven cell death in drug-resistant acute myeloid leukemia. https://doi.org/10.3390/cancers15061883HumanBlood cells
Mayayo-Vallverdu 2023 Redox Biol2023Mayayo-Vallverdú C, López de Heredia M, Prat E, González L, Espino Guarch M, Vilches C, Muñoz L, Asensi MA, Serra C, Llebaria A, Casado M, Artuch R, Garrabou G, Garcia-Roves PM, Pallardó FV, Nunes V (2023) The antioxidant l-Ergothioneine prevents cystine lithiasis in the Slc7a9-/- mouse model of cystinuria. https://doi.org/10.1016/j.redox.2023.102801MouseKidney
Fletcher 2023 Transl Res2023Fletcher E, Miserlis D, Sorokolet K, Wilburn D, Bradley C, Papoutsi E, Wilkinson T, Ring A, Ferrer L, Haynatzki G, Smith RS, Bohannon WT, Koutakis P (2023) Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease. Transl Res 260:17-31. https://doi.org/10.1016/j.trsl.2023.05.002MouseSkeletal muscle
Antona 2023 Cell Death Discov2023Antona A, Leo G, Favero F, Varalda M, Venetucci J, Faletti S, Todaro M, Mazzucco E, Soligo E, Saglietti C, Stassi G, Manfredi M, Pelicci G, Corà D, Valente G, Capello D (2023) Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation. https://doi.org/10.1038/s41420-023-01502-1HumanEndothelial;epithelial;mesothelial cell
Golomb 2023 Sci Rep2023Golomb BA, Sanchez Baez R, Schilling JM, Dhanani M, Fannon MJ, Berg BK, Miller BJ, Taub PR, Patel HH (2023) Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity. Sci Rep 13:10739. https://doi.org/10.1038/s41598-023-35896-wHumanSkeletal muscle
Wang 2023 Nature2023Wang D, Townsend LK, DesOrmeaux GJ, Frangos SM, Batchuluun B, Dumont L, Kuhre RE, Ahmadi E, Hu S, Rebalka IA, Gautam J, Jabile MJT, Pileggi CA, Rehal S, Desjardins EM, Tsakiridis EE, Lally JSV, Juracic ES, Tupling AR, Gerstein HC, Paré G, Tsakiridis T, Harper ME, Hawke TJ, Speakman JR, Blondin DP, Holloway GP, Jørgensen SB, Steinberg GR (2023) GDF15 promotes weight loss by enhancing energy expenditure in muscle. https://doi.org/10.1038/s41586-023-06249-4MouseSkeletal muscle
Kamienieva 2023 Biochim Biophys Acta Mol Basis Dis2023Kamienieva I, Charzyńska A, Duszyński J, Malińska D, Szczepanowska J (2023) In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts. https://doi.org/10.1016/j.bbadis.2023.166787HumanFibroblast
Godtliebsen 2023 Autophagy2023Godtliebsen G, Larsen KB, Bhujabal Z, Opstad IS, Nager M, Punnakkal AR, Kalstad TB, Olsen R, Lund T, Prasad DK, Agarwal K, Myrmel T, Birgisdottir AB (2023) High-resolution visualization and assessment of basal and OXPHOS-induced mitophagy in H9c2 cardiomyoblasts. https://doi.org/10.1080/15548627.2023.2230837RatHeart
Bellissimo 2023 Exp Physiol2023Bellissimo CA, Castellani LN, Finch MS, Murugathasan M, Gandhi S, Sweeney G, Abdul-Sater AA, MacPherson REK, Perry CGR (2023) Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688. https://doi.org/10.1113/ep091274MouseNervous system
Martell 2023 Acta Neuropathol Commun2023Martell E, Kuzmychova H, Senthil H, Kaul E, Chokshi CR, Venugopal C, Anderson CM, Singh SK, Sharif T (2023) Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations. https://doi.org/10.1186/s40478-023-01604-yHumanNervous system
Li 2023 Cell Rep2023Li BY, Peng WQ, Liu Y, Guo L, Tang QQ (2023) HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway. https://doi.org/10.1016/j.celrep.2023.112731
Davis 2023 MitoFit2023Davis MS, Barrett MR, Bayly WM, Bolinger A (2023) Effect of selected fluorophores on equine skeletal muscle mitochondrial respiration. MitoFit Preprints 2023.5. https://doi.org/10.26124/mitofit:2023-00052024-04-25 published in Bioenerg Commun 2024.2.HorseSkeletal muscle
Som 2023 Am J Physiol Cell Physiol2023Som R, Fink BD, Yu L, Sivitz WI (2023) Oxaloacetate regulates Complex II respiration in brown fat: dependence on UCP1 expression. Am J Physiol Cell Physiol 324:C1236-48. https://doi.org/10.1152/ajpcell.00565.2022MouseFat
Shepherd 2023 J Am Chem Soc2023Shepherd RE, Kreinbrink AC, Njimoh CL, Vali SW, Lindahl PA (2023) Yeast mitochondria import aqueous feII and, when activated for iron-sulfur cluster assembly, export or release low-molecular-mass iron and also export iron that incorporates into cytosolic proteins. https://doi.org/10.1021/jacs.2c13439
Mendoza-Fuentes 2023 PeerJ2023Mendoza-Fuentes A, González-Burgos E, Aparicio Trejo OE, Delgado-Lamas G, Rodríguez-Chávez JL, Pedraza-Chaverri J, Gómez-Serranillos MP, Araiza-Olivera D (2023) The cytotoxicity effect of 7-hydroxy-3,4-dihydrocadalene from Heterotheca inuloides and semisynthetic cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis. https://doi.org/10.7717/peerj.15586Human
Fisar 2023 Biomedicines2023Fišar Z, Hroudová J, Zvěřová M, Jirák R, Raboch J, Kitzlerová E (2023) Age-dependent alterations in platelet mitochondrial respiration. https://doi.org/10.3390/biomedicines11061564HumanPlatelet
Mancilla 2023 Physiol Rep2023Mancilla R, Pava-Mejia D, van Polanen N, de Wit V, Bergman M, Grevendonk L, Jorgensen J, Kornips E, Hoeks J, Hesselink MKC, Schrauwen-Hinderling VB (2023) Invasive and noninvasive markers of human skeletal muscle mitochondrial function. https://doi.org/10.14814/phy2.15734HumanSkeletal muscle
Gonnot 2023 Nat Commun2023Gonnot F, Boulogne L, Brun C, Dia M, Gouriou Y, Bidaux G, Chouabe C, Crola Da Silva C, Ducreux S, Pillot B, Kaczmarczyk A, Leon C, Chanon S, Perret C, Sciandra F, Dargar T, Gache V, Farhat F, Sebbag L, Bochaton T, Thibault H, Ovize M, Paillard M, Gomez L (2023) SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases. https://doi.org/10.1038/s41467-023-39027-xMouseHeart
Haney 2023 Nat Med2023Haney M, Vallée M, Fabre S, Collins Reed S, Zanese M, Campistron G, Arout CA, Foltin RW, Cooper ZD, Kearney-Ramos T, Metna M, Justinova Z, Schindler C, Hebert-Chatelain E, Bellocchio L, Cathala A, Bari A, Serrat R, Finlay DB, Caraci F, Redon B, Martín-García E, Busquets-Garcia A, Matias I, Levin FR, Felpin FX, Simon N, Cota D, Spampinato U, Maldonado R, Shaham Y, Glass M, Thomsen LL, Mengel H, Marsicano G, Monlezun S, Revest JM, Piazza PV (2023) Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials. https://doi.org/10.1038/s41591-023-02381-w
Zweck 2023 ESC Heart Fail2023Zweck E, Karschnia M, Scheiber D, Heidecke H, Dechend R, Barthuber C, Kaufmann S, Kelm M, Roden M, Westenfeld R, Szendrödi J, Boege F (2023) Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure. https://doi.org/10.1002/ehf2.14293
Duran-Gueell 2023 FASEB J2023Duran-Güell M, Garrabou G, Flores-Costa R, Casulleras M, López-Vicario C, Zhang IW, Cantó-Santos J, Contreras BJ, Sánchez-Rodríguez MB, Romero-Grimaldo B, Horrillo R, Costa M, Arroyo V, Clària J (2023) Essential role for albumin in preserving liver cells from TNFα-induced mitochondrial injury. https://doi.org/10.1096/fj.202201526rMouseLiver
Yu 2023 Biochim Biophys Acta Bioenerg2023Yu L, Fink BD, Som R, Rauckhorst AJ, Taylor EB, Sivitz WI (2023) Metabolic clearance of oxaloacetate and mitochondrial complex II respiration: Divergent control in skeletal muscle and brown adipose tissue. Biochim Biophys Acta Bioenerg 1864:148930. https://doi.org/10.1016/j.bbabio.2022.148930MouseFat
Robertson 2023 J Cell Sci2023Robertson GL, Riffle S, Patel M, Bodnya C, Marshall A, Beasley HK, Garza-Lopez E, Shao J, Vue Z, Hinton A, Stoll MS, de Wet S, Theart RP, Chakrabarty RP, Loos B, Chandel NS, Mears JA, Gama V (2023) DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. https://doi.org/10.1242/jcs.260370HumanFibroblast
Kyriazis 2023 Res Sq2023Kyriazis G, Serrano J, Boyd J, Mason C, Smith K, Karolyi K, Kondo S, Brown I, Maurya S, Meshram N, Serna V, Gilger J, Branch D, Gardell S, Baskin K, Ayala J, Pratley R, Goodpaster B, Coen P (2023) The TAS1R2 sweet taste receptor regulates skeletal muscle mass and fitness. https://doi.org/10.21203/rs.3.rs-2475555/v1MouseSkeletal muscle
Yang 2023 Cell Death Discov2023Yang H, Gao Y, Xu D, Xu K, Liang SQ, Yang Z, Scherz A, Hall SRR, Forster S, Berezowska S, Yao F, Ochsenbein AF, Marti TM, Kocher GJ, Schmid RA, Dorn P, Peng RW (2023) MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. https://doi.org/10.1038/s41420-023-01307-2HumanLung;gill
Endothelial;epithelial;mesothelial cell
Sathiaseelan 2023 J Gerontol A Biol Sci Med Sci2023Sathiaseelan R, Ahn B, Stout MB, Logan S, Wanagat J, Van M Nguyen H, Hord NG, Vandiver AR, Selvarani R, Ranjit R, Yarbrough H, Masingale A, Miller BF, Wolf RF, Austad SN, Richardson A (2023) A genetically heterogeneous rat model with divergent mitochondrial genomes. https://doi.org/10.1093/gerona/glad056RatSkeletal muscle
Gong 2023 Biomed Pharmacother2023Gong DF, Sun SC, Wang RR, Dawuti A, Kong DW, Liu RQ, Du LD, Wang SB, Lu Y, Yuan TY, Du GH, Fang LH (2023) Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy. https://doi.org/10.1016/j.biopha.2023.114382RatHeart
Dreher 2023 Int J Obes (Lond)2023Dreher SI, Irmler M, Pivovarova-Ramich O, Kessler K, Jürchott K, Sticht C, Fritsche L, Schneeweiss P, Machann J, Pfeiffer AFH, Hrabě de Angelis M, Beckers J, Birkenfeld AL, Peter A, Niess AM, Weigert C, Moller A (2023) Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention. https://doi.org/10.1038/s41366-023-01271-yHumanSkeletal muscle
Fat
Kim 2023 bioRxiv2023Kim Y, Li C, Gu C, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Fang Y, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM (2023) MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy. https://doi.org/10.1101/2023.01.10.523171MouseEndothelial;epithelial;mesothelial cell
Sumner 2023 Transl Psychiatry2023Sumner JA, Cleveland S, Chen T, Gradus JL (2023) Psychological and biological mechanisms linking trauma with cardiovascular disease risk. https://doi.org/10.1038/s41398-023-02330-8
Nord 2023 FASEB J2023Nord A, Chamkha I, Elmér E (2023) A whole blood approach improves speed and accuracy when measuring mitochondrial respiration in intact avian blood cells. https://doi.org/10.1096/fj.202201749rBirdsBlood cells
Bahire 2023 Mitochondrion2023Bahire KL, Maļuhins R, Bello F, Freitag SV, Jeļisejevs I, Gile R, Upīte J, Plesnila N, Jansone B (2023) Hemispheric analysis of mitochondrial complex I and II activity in the mouse model of ischemia-reperfusion-induced injury. https://doi.org/10.1016/j.mito.2023.02.005MouseNervous system
Mahmoud 2023 Pharmacol Res2023Mahmoud AM, Kostrzewa M, Marolda V, Cerasuolo M, Maccarinelli F, Coltrini D, Rezzola S, Giacomini A, Mollica MP, Motta A, Paris D, Zorzano A, Marzo VD, Ronca R, Ligresti A (2023) Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer. Pharmacol Res 189:106683. https://doi.org/10.1016/j.phrs.2023.106683MouseEndothelial;epithelial;mesothelial cell
Gautam 2023 Neurobiol Dis2023Gautam M, Genç B, Helmold B, Ahrens A, Kuka J, Makrecka-Kuka M, Günay A, Koçak N, Aguilar-Wickings IR, Keefe D, Zheng G, Swaminathan S, Redmon M, Zariwala HA, Özdinler PH (2023) SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function. Neurobiol Dis 178:106022. https://doi.org/10.1016/j.nbd.2023.106022RatHeart
Nervous system
Dominguez-Lopez 2023 Neuropharmacology2023Dominguez-Lopez S, Ahn B, Sataranatarajan K, Ranjit R, Premkumar P, Van Remmen H, Beckstead MJ (2023) Long-term methamphetamine self-administration increases mesolimbic mitochondrial oxygen consumption and decreases striatal glutathione. Neuropharmacology 227:109436. https://doi.org/10.1016/j.neuropharm.2023.109436MouseNervous system
Wu 2023 Int Immunopharmacol2023Wu F, Zhang YT, Teng F, Li HH, Guo SB (2023) S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fission and respiratory dysfunction. https://doi.org/10.1016/j.intimp.2023.109716MouseHeart
Kulkarni 2023 FASEB J2023Kulkarni PP, Ekhlak M, Singh V, Kailashiya V, Singh N, Dash D (2023) Fatty acid oxidation fuels agonist-induced platelet activation and thrombus formation: Targeting β-oxidation of fatty acids as an effective anti-platelet strategy. https://doi.org/10.1096/fj.202201321rr
Pavluch 2023 Sci Rep2023Pavluch V, Engstová H, Špačková J, Ježek P (2023) Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells. https://doi.org/10.1038/s41598-023-27985-7RatIslet cell;pancreas;thymus
Vilas-Boas 2023 J Biol Chem2023Vilas-Boas EA, Cabral-Costa JV, Ramos VM, Caldeira da Silva CC, Kowaltowski AJ (2023) Goldilocks calcium concentrations and the regulation of oxidative phosphorylation: too much, too little, or just right. https://doi.org/10.1016/j.jbc.2023.102904MouseLiver
Thoral 2023 J Exp Biol2023Thoral E, Roussel D, Gasset E, Dutto G, Queiros Q, McKenzie DJ, Bourdeix JH, Metral L, Saraux C, Teulier L (2023) Temperature-dependent metabolic consequences of food deprivation in the European sardine. https://doi.org/10.1242/jeb.244984FishesSkeletal muscle
Mioc 2023 Molecules2023Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. https://doi.org/10.3390/molecules28010421HumanEndothelial;epithelial;mesothelial cell
Marin 2023 Exp Gerontol2023Marin CT, de Souza Lino AD, Avelar IDS, Barbosa MR, Scarlato GCG, Cavalini DF, Tamanini F, Alexandrino AV, Vercesi AE, Shiguemoto GE (2023) Resistance training prevents dynamics and mitochondrial respiratory dysfunction in vastus lateralis muscle of ovariectomized rats. https://doi.org/10.1016/j.exger.2023.112081RatSkeletal muscle
Calabria 2023 Biomedicines2023Calabria E, Muollo V, Cavedon V, Capovin T, Saccenti L, Passarotti F, Ghiotto L, Milanese C, Gelati M, Rudi D, Salvagno GL, Lippi G, Tam E, Schena F, Pogliaghi S (2023) Type 2 diabetes related mitochondrial defects in peripheral mononucleated blood cells from overweight postmenopausal women. Biomedicines 11:121. https://doi.org/10.3390/biomedicines11010121HumanBlood cells
Horvath 2023 Antioxidants (Basel)2023Horváth T, Sándor L, Baráth B, Donka T, Baráth B, Mohácsi Á, Jász KD, Hartmann P, Boros M (2023) Methane admixture protects liver mitochondria and improves graft function after static cold storage and reperfusion. Antioxidants (Basel) 12:271. https://doi.org/10.3390/antiox12020271RatLiver
Hoogstraten 2023 Arch Toxicol2023Hoogstraten CA, Jacobs MME, de Boer G, van de Wal MAE, Koopman WJH, Smeitink JAM, Russel FGM, Schirris TJJ (2023) Metabolic impact of genetic and chemical ADP/ATP carrier inhibition in renal proximal tubule epithelial cells. https://doi.org/10.1007/s00204-023-03510-7HumanKidney
Kalia 2023 Cell Rep2023Kalia NP, Singh S, Hards K, Cheung CY, Sviriaeva E, Banaei-Esfahani A, Aebersold R, Berney M, Cook GM, Pethe K (2023) M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments. https://doi.org/10.1016/j.celrep.2023.112444Eubacteria
Shi 2023 Redox Biol2023Shi L, Tao Z, Zheng L, Yang J, Hu X, Scott K, de Kloet A, Krause E, Collins JF, Cheng Z (2023) FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway. https://doi.org/10.1016/j.redox.2023.102727MouseFat
Horcas-Nieto 2023 Biochim Biophys Acta Mol Basis Dis2023Horcas-Nieto JM, Versloot CJ, Langelaar-Makkinje M, Gerding A, Blokzijl T, Koster MH, Baanstra M, Martini IA, Coppes RP, Bourdon C, van Ijzendoorn SCD, Kim P, Bandsma RHJ, Bakker BM (2023) Organoids as a model to study intestinal and liver dysfunction in severe malnutrition. https://doi.org/10.1016/j.bbadis.2022.166635MouseLiver
Other cell lines
Devaux 2023 J Comp Physiol B2023Devaux JBL, Hedges CP, Birch N, Herbert N, Renshaw GMC, Hickey AJR (2023) Electron transfer and ROS production in brain mitochondria of intertidal and subtidal triplefin fish (Tripterygiidae). J Comp Physiol B 193:413-24. https://doi.org/10.1007/s00360-023-01495-4FishesNervous system
Martell 2023 Nat Commun2023Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury SR, Morrison LC, Fresnoza A, Zagozewski J, Venugopal C, Anderson CM, Singh SK, Banerji V, Werbowetski-Ogilvie TE, Sharif T (2023) Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. https://doi.org/10.1038/s41467-023-38049-9HumanNervous system
Luther 2023 Am J Physiol Renal Physiol2023Luther T, Bülow Anderberg S, Persson P, Franzén S, Skorup P, Wernerson A, Hultenby K, Palm F, Schiffer TA, Frithiof R (2023) Renal mitochondrial dysfunction in ovine experimental sepsis associated acute kidney injury. https://doi.org/10.1152/ajprenal.00294.2022Other mammalsKidney
Ashok 2023 Mol Cell Biochem2023Ashok S, Raji SR, Manjunatha S, Srinivas G (2023) Impairment of substrate-mediated mitochondrial respiration in cardiac cells by chloroquine. https://doi.org/10.1007/s11010-023-04740-0MouseHeart
Dias 2023 Biofactors2023Dias C, Fernandes E, Barbosa RM, Laranjinha J, Ledo A (2023) Astrocytic aerobic glycolysis provides lactate to support neuronal oxidative metabolism in the hippocampus. https://doi.org/10.1002/biof.1951RatNervous system
Naghipour 2023 Dis Model Mech2023Naghipour S, Fisher JJ, Perkins AV, Peart JN, Headrick JP, Du Toit EF (2023) Trimethylamine-N-oxide paradoxically depresses contractile function while activating mitochondrial respiration in mouse hearts. https://doi.org/10.1242/dmm.049975
Scandalis 2023 JAMA Cardiol2023Scandalis L, Kitzman DW, Nicklas BJ, Lyles M, Brubaker P, Nelson MB, Gordon M, Stone J, Bergstrom J, Neufer PD, Gnaiger E, Molina AJA (2023) Skeletal muscle mitochondrial respiration and exercise intolerance in patients with heart failure with preserved ejection fraction. JAMA Cardiol 8:575–84. https://doi.org/10.1001/jamacardio.2023.0957HumanSkeletal muscle
Salmon 2023 Geroscience2023Salmón P, Millet C, Selman C, Monaghan P, Dawson NJ (2023) Tissue-specific reductions in mitochondrial efficiency and increased ROS release rates during ageing in zebra finches, Taeniopygia guttata. Geroscience 45:265-76. https://doi.org/10.1007/s11357-022-00624-1BirdsSkeletal muscle
Liver
Koizumi 2023 Front Cardiovasc Med2023Koizumi T, Watanabe M, Yokota T, Tsuda M, Handa H, Koya J, Nishino K, Tatsuta D, Natsui H, Kadosaka T, Koya T, Nakao M, Hagiwara H, Kamada R, Temma T, Tanaka S, Anzai T (2023) Empagliflozin suppresses mitochondrial reactive oxygen species generation and mitigates the inducibility of atrial fibrillation in diabetic rats. Front Cardiovasc Med 10: 1005408.RatHeart
Shirakawa 2023 Sci Rep2023Shirakawa R, Nakajima T, Yoshimura A, Kawahara Y, Orito C, Yamane M, Handa H, Takada S, Furihata T, Fukushima A, Ishimori N, Nakagawa M, Yokota I, Sabe H, Hashino S, Kinugawa S, Yokota T (2023) Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults. Sci Rep 13:5203. https://doi.org/10.1038/s41598-023-32549-wHumanBlood cells
Temelie 2023 Int J Mol Sci2023Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. https://doi.org/10.3390/ijms24065891MouseFibroblast
Galli 2023 Comp Biochem Physiol A Mol Integr Physiol2023Galli GLJ, Shiels HA, White E, Couturier CS, Stecyk JAW (2023) The air-breathing Alaska blackfish (Dallia pectoralis) suppresses brain mitochondrial reactive oxygen species to survive cold hypoxic winters. https://doi.org/10.1016/j.cbpa.2022.111355FishesNervous system
Inoue 2023 Sci Rep2023Inoue R, Miura M, Yanai S, Nishimune H (2023) Coenzyme Q10 supplementation improves the motor function of middle-aged mice by restoring the neuronal activity of the motor cortex. https://doi.org/10.1038/s41598-023-31510-1Nervous system
Vamesu 2023 JCI Insight2023Vamesu BM, Nicola T, Li R, Hazra S, Matalon S, Kaminski N, Ambalavanan N, Kandasamy J (2023) Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function. https://doi.org/10.1172/jci.insight.160697MouseLung;gill
Doke 2023 Nat Metab2023Doke T, Mukherjee S, Mukhi D, Dhillon P, Abedini A, Davis JG, Chellappa K, Chen B, Baur JA, Susztak K (2023) NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury. https://doi.org/10.1038/s42255-023-00761-7HumanKidney
Pacheco-Fuentes 2023 Oecologia2023Pacheco-Fuentes H, Ton R, Griffith SC (2023) Short- and long-term consequences of heat exposure on mitochondrial metabolism in zebra finches (Taeniopygia castanotis). https://doi.org/10.1007/s00442-023-05344-7BirdsBlood cells
Leduc-Gaudet 2023 Nat Commun2023Leduc-Gaudet JP, Franco-Romero A, Cefis M, Moamer A, Broering FE, Milan G, Sartori R, Chaffer TJ, Dulac M, Marcangeli V, Mayaki D, Huck L, Shams A, Morais JA, Duchesne E, Lochmuller H, Sandri M, Hussain SNA, Gouspillou G (2023) MYTHO is a novel regulator of skeletal muscle autophagy and integrity. Nat Commun 14:1199. https://doi.org/10.1038/s41467-023-36817-1MouseSkeletal muscle
Cortes 2023 Nat Commun2023Cortés M, Brischetto A, Martinez-Campanario MC, Ninfali C, Domínguez V, Fernández S, Celis R, Esteve-Codina A, Lozano JJ, Sidorova J, Garrabou G, Siegert AM, Enrich C, Pintado B, Morales-Ruiz M, Castro P, Cañete JD, Postigo A (2023) Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation. https://doi.org/10.1038/s41467-023-42277-4HumanBlood cells
Liu 2023 Pharmacol Res2023Liu S, Yue S, Guo Y, Han JY, Wang H (2023) Sorafenib induces cardiotoxicity through RBM20-mediated alternative splicing of sarcomeric and mitochondrial genes. https://doi.org/10.1016/j.phrs.2023.107017RatHeart
Davis 2023 Am J Physiol Regul Integr Comp Physiol .2023Davis MS, Bayly WM, Hansen CM, Barrett MR, Blake CA (2023) Effects of hyperthermia and acidosis on mitochondrial production of reactive oxygen species. Am J Physiol Regul Integr Comp Physiol 325:R725-34. https://doi.org/10.1152/ajpregu.00177.2023HorseSkeletal muscle
Urzi 2023 Anal Chem2023Urzì C, Meyer C, Nuoffer JM, Vermathen P (2023) Methods for oxygen determination in an NMR bioreactor as a surrogate marker for metabolomic studies in living cell cultures. Anal Chem 95:17486-93. https://doi.org/10.1021/acs.analchem.3c02314
Kumar 2023 J Nutr Biochem2023Kumar A, Bellar A, Mishra S, Sekar J, Welch N, Dasarathy S (2023) L-Isoleucine reverses hyperammonemia-induced myotube mitochondrial dysfunction and post-mitotic senescence. https://doi.org/10.1016/j.jnutbio.2023.109498
Sundaram 2023 Cell Metab2023Sundaram VK, Schütza V, Schröter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Schäffner E, Sánchez EE, Akkermann D, Paul C, Schwagarus N, Müller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R (2023) Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration. https://doi.org/10.1016/j.cmet.2023.10.017MouseNervous system
Batterson 2023 Physiol Rep2023Batterson PM, McGowan EM, Borowik AK, Kinter MT, Miller BF, Newsom SA, Robinson MM (2023) High-fat diet increases electron transfer flavoprotein synthesis and lipid respiration in skeletal muscle during exercise training in female mice. Physiol Rep 11:e15840. https://doi.org/10.14814/phy2.15840MouseSkeletal muscle
Bodis 2023 Diabetes Obes Metab2023Bódis K, Breuer S, Crepzia-Pevzner A, Zaharia OP, Schön M, Saatmann N, Altenhofen D, Springer C, Szendroedi J, Wagner R, Al-Hasani H, Roden M, Pesta D, Chadt A (2023) Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model. https://doi.org/10.1111/dom.15322MouseFat
Campesan 2023 Neurobiol Dis2023Campesan S, Del Popolo I, Marcou K, Straatman-Iwanowska A, Repici M, Boytcheva KV, Cotton VE, Allcock N, Rosato E, Kyriacou CP, Giorgini F (2023) Bypassing mitochondrial defects rescues Huntington's phenotypes in Drosophila. https://doi.org/10.1016/j.nbd.2023.106236
Konadu 2023 Front Physiol2023Konadu B, Hosler JP, Gibert Y, Edwards KS (2023) Analysis of oxygen consumption rates in zebrafish reveals differences based on sex, age and physical activity recovery. Front Physiol 14:1272366. https://doi.org/10.3389/fphys.2023.1272366Zebrafish
Fishes
Silva 2023 Cells2023Silva EA, Dalla Costa AP, Ruas JS, Siqueira-Santos ES, Francisco A, Castilho RF (2023) Proliferating astrocytes in primary culture do not depend upon mitochondrial respiratory Complex I activity or oxidative phosphorylation. Cells 12:683. https://doi.org/10.3390/cells12050683MouseNervous system
Wang 2023 Clin Exp Pharmacol Physiol2023Wang S, Liu W, Liu S, Li J, Geng Y, Zhao Y (2023) Improved cardioprotective effect of 3-nitro-N-methyl salicylamide solution after a prolonged preservation time of rat heart. https://doi.org/10.1111/1440-1681.13835RatHeart
Santos-Silva 2023 Transl Psychiatry2023Santos-Silva T, Hazar Ülgen D, Lopes CFB, Guimarães FS, Alberici LC, Sandi C, Gomes FV (2023) Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response. https://doi.org/10.1038/s41398-023-02648-3RatNervous system
Zhang 2023 Nat Commun2023Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C (2023) ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. https://doi.org/10.1038/s41467-023-43439-0MouseLiver
Pinho 2023 Eur J Clin Invest2023Pinho ACO, Santos D, Oliveira PJ, Leal EC, Carvalho E (2023) Real-time OXPHOS capacity analysis in wounded skin from diabetic mice: A pilot study. https://doi.org/10.1111/eci.14128Mouse
Kutschka 2023 Basic Res Cardiol2023Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J (2023) Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. https://doi.org/10.1007/s00395-023-01017-xMouseHeart
Silva Dias Vieira 2023 PLoS Negl Trop Dis2023Silva Dias Vieira C, Pinheiro Aguiar R, de Almeida Nogueira NP, Costa Dos Santos Junior G, Paes MC (2023) Glucose metabolism sustains heme-induced Trypanosoma cruzi epimastigote growth in vitro. https://doi.org/10.1371/journal.pntd.0011725Protists
Jiang 2023 Sci Rep2023Jiang N, Wang Z, Guo X, Peng Z, He Y, Wang Q, Wu H, Cui Y (2023) Hepatic Runx1t1 improves body fat index after endurance exercise in obese mice. https://doi.org/10.1038/s41598-023-46302-wMouseLiver
Ismaeel 2023 Physiol Rep2023Ismaeel A, Valentino TR, Burke B, Goh J, Saliu TP, Albathi F, Owen A, McCarthy JJ, Wen Y (2023) Acetate and succinate benefit host muscle energetics as exercise-associated post-biotics. https://doi.org/10.14814/phy2.15848MouseSkeletal muscle
Zvejniece 2023 Biomed Pharmacother2023Zvejniece L, Svalbe B, Vavers E, Ozola M, Grinberga S, Gukalova B, Sevostjanovs E, Liepinsh E, Dambrova M (2023) Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats. Biomed Pharmacother 168:115803. https://doi.org/10.1016/j.biopha.2023.115803Rat
Mazaki 2023 Cell Commun Signal2023Mazaki Y, Handa H, Fumoto Y, Horinouchi T, Onodera Y (2023) LRRK2 is involved in the chemotaxis of neutrophils and differentiated HL-60 cells, and the inhibition of LRRK2 kinase activity increases fMLP-induced chemotactic activity. https://doi.org/10.1186/s12964-023-01305-yHumanBlood cells
Sharma 2023 Biosci Biotechnol Biochem2023Sharma S, Zhang X, Azhar G, Patyal P, Verma A, Kc G, Wei JY (2023) Valine improves mitochondrial function and protects against oxidative stress. Biosci Biotechnol Biochem 88:168-76. https://doi.org/10.1093/bbb/zbad169MouseSkeletal muscle
Whytock 2023 Am J Physiol Endocrinol Metab2023Whytock KL, Pino MF, Sun Y, Yu G, De Carvalho FG, Yeo RX, Vega RB, Parmar G, Divoux A, Kapoor N, Yi F, Cornnell H, Patten DA, Harper ME, Gardell SJ, Smith SR, Walsh MJ, Sparks LM (2023) Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity. https://doi.org/10.1152/ajpendo.00143.2023
Chen 2023 Nat Commun2023Chen M, Zhu JY, Mu WJ, Luo HY, Li Y, Li S, Yan LJ, Li RY, Guo L (2023) Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice. https://doi.org/10.1038/s41467-023-44242-7HumanLiver
Purhonen 2023 Nat Commun2023Purhonen J, Banerjee R, Wanne V, Sipari N, Mörgelin M, Fellman V, Kallijärvi J (2023) Mitochondrial complex III deficiency drives c-MYC overexpression and illicit cell cycle entry leading to senescence and segmental progeria. Nat Commun 14:2356. https://doi.org/10.1038/s41467-023-38027-1MouseLiver
Kidney
Perin 2023 Proc Natl Acad Sci U S A2023Perin G, Bellan A, Michelberger T, Lyska D, Wakao S, Niyogi KK, Morosinotto T (2023) Modulation of xanthophyll cycle impacts biomass productivity in the marine microalga Nannochloropsis. Proc Natl Acad Sci U S A 120:e2214119120. https://doi.org/10.1073/pnas.2214119120Algae
Yang 2023 Redox Biol2023Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z (2023) Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis. https://doi.org/10.1016/j.redox.2023.103002HumanLiver
Curtabbi 2023 Redox Biol2023Curtabbi A, Guarás A, Cabrera-Alarcón JL, Rivero M, Calvo E, Rosa-Moreno M, Vázquez J, Medina M, Enríquez JA (2023) Regulation of respiratory complex I assembly by FMN cofactor targeting. Redox Biol 69:103001. https://doi.org/10.1016/j.redox.2023.103001MouseFibroblast
Kidney
Janz 2023 Mol Metab2023Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B (2023) Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes. https://doi.org/10.1016/j.molmet.2023.101859HumanHeLa
Blackwell 2023 Prostate Cancer Prostatic Dis2023Blackwell JEM, Gharahdaghi N, Deane CS, Brook MS, Williams JP, Lund JN, Atherton PJ, Smith K, Wilkinson DJ, Phillips BE (2023) Molecular mechanisms underpinning favourable physiological adaptations to exercise prehabilitation for urological cancer surgery. https://doi.org/10.1038/s41391-023-00774-z
Gaudo 2023 Free Radic Biol Med2023Gaudó P, de Tomás-Mateo E, Garrido-Pérez N, Santana A, Ruiz-Pesini E, Montoya J, Bayona-Bafaluy P (2023) "ATAD3C regulates ATAD3A assembly and function in the mitochondrial membrane". https://doi.org/10.1016/j.freeradbiomed.2023.12.006HumanFibroblast
Dabrowska 2023 Int J Mol Sci2023Dabrowska A, Zajac M, Bednarczyk P, Lukasiak A (2023) Effect of quercetin on mitoBKCa channel and mitochondrial function in human bronchial epithelial cells exposed to particulate matter. Int J Mol Sci 24:638. https://doi.org/10.3390/ijms24010638HumanLung;gill
Endothelial;epithelial;mesothelial cell
Garcia-Roche 2023 PLoS One2023García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Cassina A, Quijano C, Carriquiry M (2023) Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. https://doi.org/10.1371/journal.pone.0290551BovinesLiver
Wang 2023 Cancer Cell Int2023Wang Y, Wang J, Chen L, Chen Z, Wang T, Xiong S, Zhou T, Wu G, He L, Cao J, Liu M, Li H, Gu H (2023) PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis. https://doi.org/10.1186/s12935-023-03178-0HumanEndothelial;epithelial;mesothelial cell
Bassot 2023 Cell Rep2023Bassot A, Chen J, Takahashi-Yamashiro K, Yap MC, Gibhardt CS, Le GNT, Hario S, Nasu Y, Moore J, Gutiérrez T, Mina L, Mast H, Moses A, Bhat R, Ballanyi K, Lemieux H, Sitia R, Zito E, Bogeski I, Campbell RE, Simmen T (2023) The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria. Cell Rep 42:111899. https://doi.org/10.1016/j.celrep.2022.111899Human
Mouse
HEK
Fibroblast
Noone 2023 J Physiol2023Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. https://doi.org/10.1113/jp284734HumanSkeletal muscle
Harmsen 2023 J Physiol2023Harmsen JF, Kotte M, Habets I, Bosschee F, Frenken K, Jorgensen JA, de Kam S, Moonen-Kornips E, Cissen J, Doligkeit D, van de Weijer T, Erazo-Tapia E, Buitinga M, Hoeks J, Schrauwen P (2023) Exercise training modifies skeletal muscle clock gene expression but not 24-hour rhythmicity in substrate metabolism of men with insulin resistance. https://doi.org/10.1113/jp285523HumanSkeletal muscle
Fernando 2023 Commun Biol2023Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. https://doi.org/10.1038/s42003-023-05595-3MouseSkeletal muscle
Stouth 2023 Autophagy2023Stouth DW, vanLieshout TL, Mikhail AI, Ng SY, Raziee R, Edgett BA, Vasam G, Webb EK, Gilotra KS, Markou M, Pineda HC, Bettencourt-Mora BG, Noor H, Moll Z, Bittner ME, Gurd BJ, Menzies KJ, Ljubicic V (2023) CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy. Autophagy 20:1247-69. https://doi.org/10.1080/15548627.2023.2288528MouseSkeletal muscle
Verma 2023 Int J Mol Sci2023Verma A, Azhar G, Zhang X, Patyal P, Kc G, Sharma S, Che Y, Wei JY (2023) P. gingivalis-LPS induces mitochondrial dysfunction mediated by neuroinflammation through oxidative stress. Int J Mol Sci 24:950. https://doi.org/10.3390/ijms24020950HumanEndothelial;epithelial;mesothelial cell
Glombik 2023 Int J Mol Sci2023Glombik K, Kukla-Bartoszek M, Curzytek K, Detka J, Basta-Kaim A, Budziszewska B (2023) The effects of prenatal dexamethasone exposure on brain metabolic homeostasis in adulthood: implications for depression. Int J Mol Sci 24:1156. https://doi.org/10.3390/ijms24021156RatNervous system
Wen 2023 PLoS One2023Wen W, Guo C, Chen Z, Yang D, Zhu D, Jing Q, Zheng L, Sun C, Tang C (2023) Regular exercise attenuates alcoholic myopathy in zebrafish by modulating mitochondrial homeostasis. https://doi.org/10.1371/journal.pone.0294700Zebrafish
Fishes
Skeletal muscle
Ren 2023 Cell Discov2023Ren X, Yan J, Zhao Q, Bao X, Han X, Zheng C, Zhou Y, Chen L, Wang B, Yang L, Lin X, Liu D, Lin Y, Li M, Fang H, Lu Z, Lyu J (2023) The Fe-S cluster assembly protein IscU2 increases α-ketoglutarate catabolism and DNA 5mC to promote tumor growth. https://doi.org/10.1038/s41421-023-00558-8HumanIslet cell;pancreas;thymus
Ling 2023 EBioMedicine2023Ling C, Versloot CJ, Arvidsson Kvissberg ME, Hu G, Swain N, Horcas-Nieto JM, Miraglia E, Thind MK, Farooqui A, Gerding A, van Eunen K, Koster MH, Kloosterhuis NJ, Chi L, ChenMi Y, Langelaar-Makkinje M, Bourdon C, Swann J, Smit M, de Bruin A, Youssef SA, Feenstra M, van Dijk TH, Thedieck K, Jonker JW, Kim PK, Bakker BM, Bandsma RHJ (2023) Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition. https://doi.org/10.1016/j.ebiom.2023.104809Mouse
Flockhart 2023 Redox Biol2023Flockhart M, Nilsson LC, Tillqvist EN, Vinge F, Millbert F, Lännerström J, Nilsson PH, Samyn D, Apró W, Sundqvist ML, Larsen FJ (2023) Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training. https://doi.org/10.1016/j.redox.2023.102873
Colosio 2023 J Appl Physiol (1985)2023Colosio M, Brocca L, Gatti M, Neri M, Crea E, Cadile F, Canepari M, Pellegrino MA, Polla B, Porcelli S, Bottinelli R (2023) Structural and functional impairments of skeletal muscle in patients with post-acute sequelae of SARS-CoV-2 infection. https://doi.org/10.1152/japplphysiol.00158.2023HumanSkeletal muscle
Morales-Rubio 2023 Sci Rep2023Morales-Rubio R, Bernal-Ramírez J, Rubio-Infante N, Luévano-Martínez LA, Ríos A, Escalante BA, García-Rivas G, Rodríguez González J (2023) Cellular shortening and calcium dynamics are improved by noisy stimulus in a model of cardiomyopathy. https://doi.org/10.1038/s41598-023-41611-6MouseHeart
Sadri 2023 Function (Oxf)2023Sadri S, Zhang X, Audi SH, Cowley AW Jr, Dash RK (2023) Computational modeling of substrate-dependent mitochondrial respiration and bioenergetics in the heart and kidney cortex and outer medulla. Function (Oxf) 4:zqad038. https://doi.org/10.1093/function/zqad038RatHeart
Kidney
Krause 2023 J Transl Med2023Krause J, Nickel A, Madsen A, Aitken-Buck HM, Stoter AMS, Schrapers J, Ojeda F, Geiger K, Kern M, Kohlhaas M, Bertero E, Hofmockel P, Hübner F, Assum I, Heinig M, Müller C, Hansen A, Krause T, Park DD, Just S, Aïssi D, Börnigen D, Lindner D, Friedrich N, Alhussini K, Bening C, Schnabel RB, Karakas M, Iacoviello L, Salomaa V, Linneberg A, Tunstall-Pedoe H, Kuulasmaa K, Kirchhof P, Blankenberg S, Christ T, Eschenhagen T, Lamberts RR, Maack C, Stenzig J, Zeller T (2023) An arrhythmogenic metabolite in atrial fibrillation. J Transl Med 21:566. https://doi.org/10.1186/s12967-023-04420-zHumanHeart
Correia 2023 Endocrinology2023Correia CM, Præstholm SM, Havelund JF, Pedersen FB, Siersbæk MS, Ebbesen MF, Gerhart-Hines Z, Heeren J, Brewer J, Larsen S, Blagoev B, Færgeman NJ, Grøntved L (2023) Acute deletion of the glucocorticoid receptor in hepatocytes disrupts postprandial lipid metabolism in male mice. Endocrinology 164:bqad128. https://doi.org/10.1210/endocr/bqad128Mouse
Fleischman 2023 Mol Metab2023Fleischman JY, Van den Bergh F, Collins NL, Bowers M, Beard DA, Burant CF (2023) Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness. https://doi.org/10.1016/j.molmet.2023.101793RatHeart
Skeletal muscle
Nijholt 2023 Sci Rep2023Nijholt KT, Sánchez-Aguilera PI, Mahmoud B, Gerding A, Wolters JC, Wolters AHG, Giepmans BNG, Silljé HHW, de Boer RA, Bakker BM, Westenbrink BD (2023) A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise. https://doi.org/10.1038/s41598-023-45961-zMouseHeart
Awad-Igbaria 2023 J Transl Med2023Awad-Igbaria Y, Ferreira N, Keadan A, Sakas R, Edelman D, Shamir A, Francous-Soustiel J, Palzur E (2023) HBO treatment enhances motor function and modulates pain development after sciatic nerve injury via protection the mitochondrial function. https://doi.org/10.1186/s12967-023-04414-xRatNervous system
Bowering 2023 Front Physiol2023Bowering LR, McArley TJ, Devaux JBL, Hickey AJR, Herbert NA (2023) Metabolic resilience of the Australasian snapper (Chrysophrys auratus) to marine heatwaves and hypoxia. https://doi.org/10.3389/fphys.2023.1215442FishesHeart
Arias-Reyes 2023 MitoFit2023Arias-Reyes C, Aliaga-Raduán F, Pinto-Aparicio R, Joseph V, Soliz J (2023) Mitochondrial plasticity in the retrosplenial cortex enhances ATP synthesis during acclimatization to hypoxia in mice but not in rats. MitoFit Preprints 2023.6. https://doi.org/10.26124/mitofit:2023-0006Mouse
Rat
Nervous system
Thompson 2023 Geroscience2023Thompson SD, Barrett KL, Rugel CL, Redmond R, Rudofski A, Kurian J, Curtin JL, Dayanidhi S, Lavasani M (2023) Sex-specific preservation of neuromuscular function and metabolism following systemic transplantation of multipotent adult stem cells in a murine model of progeria. https://doi.org/10.1007/s11357-023-00892-5MouseSkeletal muscle
Deschemin 2023 Sci Rep2023Deschemin JC, Ransy C, Bouillaud F, Chung S, Galy B, Peyssonnaux C, Vaulont S (2023) Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis. https://doi.org/10.1038/s41598-023-39305-0MouseFat
Mousa 2023 Cell Rep2023Mousa MG, Vuppaladhadiam L, Kelly MO, Pietka T, Ek S, Shen KC, Meyer GA, Finck BN, Brookheart RT (2023) Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51. Cell Rep 42:112336. https://doi.org/10.1016/j.celrep.2023.112336MouseSkeletal muscle
Kim 2023 Nat Commun2023Kim Y, Li C, Gu C, Fang Y, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM (2023) MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice. Nat Commun 14:6493. https://doi.org/10.1038/s41467-023-42154-0MouseKidney
Sucha 2023 Int J Mol Sci2023Sucha M, Benediktova S, Tichanek F, Jedlicka J, Kapl S, Jelinkova D, Purkartova Z, Tuma J, Kuncova J, Cendelin J (2023) Experimental treatment with edaravone in a mouse model of spinocerebellar ataxia 1. https://doi.org/10.3390/ijms241310689MouseNervous system
Radaelli 2023 Elife2023Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M (2023) Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis. https://doi.org/10.7554/elife.84710
Strogulski 2023 J Neurochem2023Strogulski NR, Portela LV, Polster BM, Loane DJ (2023) Fundamental neurochemistry review: microglial immunometabolism in traumatic brain injury. https://doi.org/10.1111/jnc.15959
Boykov 2023 Sci Rep2023Boykov IN, Montgomery MM, Hagen JT, Aruleba RT, McLaughlin KL, Coalson HS, Nelson MA, Pereyra AS, Ellis JM, Zeczycki TN, Vohra NA, Tan SF, Cabot MC, Fisher-Wellman KH (2023) Pan-tissue mitochondrial phenotyping reveals lower OXPHOS expression and function across cancer types. https://doi.org/10.1038/s41598-023-43963-5MouseHeart
Endothelial;epithelial;mesothelial cell
Walsh 2023 FASEB J2023Walsh MA, Musci RV, Jacobs RA, Hamilton KL (2023) A practical perspective on how to develop, implement, execute, and reproduce high-resolution respirometry experiments: The physiologist's guide to an Oroboros O2k. https://doi.org/10.1096/fj.202301644rr
Tian 2023 Redox Biol2023Tian G, Zhou J, Quan Y, Kong Q, Li J, Xin Y, Wu W, Tang X, Liu X (2023) Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism. https://doi.org/10.1016/j.redox.2023.102907MouseHeart
Fibroblast
Menail 2023 FASEB J2023Menail HA, Cormier SB, Léger A, Robichaud S, Hebert-Chatelain E, Lamarre SG, Pichaud N (2023) Age-related flexibility of energetic metabolism in the honey bee Apis mellifera. https://doi.org/10.1096/fj.202300654rHexapods
Luptak 2023 Antioxidants (Basel)2023Ľupták M, Fišar Z, Hroudová J (2023) Different effects of SSRIs, Bupropion, and Trazodone on mitochondrial functions and monoamine oxidase isoform activity. Antioxidants (Basel) 12:1208. https://doi.org/10.3390/antiox12061208PigNervous system
Sadri 2023 Arch Biochem Biophys2023Sadri S, Tomar N, Yang C, Audi SH, Cowley AW Jr, Dash RK (2023) Effects of ROS pathway inhibitors and NADH and FADH2 linked substrates on mitochondrial bioenergetics and ROS emission in the heart and kidney cortex and outer medulla. Arch Biochem Biophys 744:109690. https://doi.org/10.1016/j.abb.2023.109690RatHeart
Kidney
Mu 2023 STAR Protoc2023Mu C, Shearer J (2023) Protocol for measuring respiratory function of mitochondria in frozen colon tissue from rats. https://doi.org/10.1016/j.xpro.2023.102560RatEndothelial;epithelial;mesothelial cell
Nastasi 2023 J Inorg Biochem2023Nastasi MR, Borisov VB, Forte E (2023) The terminal oxidase cytochrome bd-I confers carbon monoxide resistance to Escherichia coli cells. https://doi.org/10.1016/j.jinorgbio.2023.112341
Heo 2023 J Cachexia Sarcopenia Muscle2023Heo J, Schifino AG, McFaline-Figueroa J, Miller DL, Hoffman JR, Noble EE, Greising SM, Call JA (2023) Differential effects of Western diet and traumatic muscle injury on skeletal muscle metabolic regulation in male and female mice. https://doi.org/10.1002/jcsm.13361MouseSkeletal muscle
Ebanks 2023 PLoS One2023Ebanks B, Kwiecinska P, Moisoi N, Chakrabarti L (2023) A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer. https://doi.org/10.1371/journal.pone.0276147Mouse
Drosophila
Skeletal muscle
Noone 2023 Cell Signal2023Noone J, Rochfort KD, O'Sullivan F, O'Gorman DJ (2023) SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. https://doi.org/10.1016/j.cellsig.2023.110931HumanSkeletal muscle
Wilkinson 2023 Trends Endocrinol Metab2023Wilkinson MS, Dunham-Snary KJ (2023) Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease. Trends Endocrinol Metab 34:554-70. https://doi.org/10.1016/j.tem.2023.06.004
MiPNet27.10 IOC156 Ramat Gan IL2022-11-28
Oroboros Network
Ramat Gan IL, 2022 Nov 28-30 Oroboros Workshop on high-resolution respirometry (HRR), IOC156.
MiPNet26.14 Oxia2022-10-31
O2k-Manual
Oxia - HyperOxia to HypOxia.
MiPNet27.07 Sample Holder2022-08-09
O2k-Manual
Sample Holder.
MiPNet26.13 NextGen-O2k Series XA Manual2022-07-25
O2k-Manual
NextGen-O2k Series XA Manual.
MiPNet26.12 NextGen-O2k: NADH-Module2022-05-17
O2k-Manual
NextGen-O2k: NADH-Module manual
MiPNet28.07 NextGen-O2k Series XB Manual2022-02-20
O2k-Manual
NextGen-O2k Series XB Manual.
Fink 2022 FASEB Bioadv2022Fink BD, Rauckhorst AJ, Taylor EB, Yu L, Sivitz WI (2022) Membrane potential-dependent regulation of mitochondrial complex II by oxaloacetate in interscapular brown adipose tissue. FASEB Bioadv 4:197-210. https://doi.org/10.1096/fba.2021-00137Fat
Desjardins 2022 Proc Natl Acad Sci U S A2022Desjardins EM, Smith BK, Day EA, Ducommun S, Sanders MJ, Nederveen JP, Ford RJ, Pinkosky SL, Townsend LK, Gutgesell RM, Lu R, Sakamoto K, Steinberg GR (2022) The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids. https://doi.org/10.1073/pnas.2119824119MouseLiver
Scrima 2022 Stem Cell Res Ther2022Scrima R, Agriesti F, Pacelli C, Piccoli C, Pucci P, Amoresano A, Cela O, Nappi L, Tataranni T, Mori G, Formisano P, Capitanio N (2022) Myoglobin expression by alternative transcript in different mesenchymal stem cells compartments. https://doi.org/10.1186/s13287-022-02880-6HumanStem cells
Ma 2022 Int J Obes (Lond)2022Ma H, He C, Li L, Gao P, Lu Z, Hu Y, Wang L, Zhao Y, Cao T, Cui Y, Zheng H, Yang G, Yan Z, Liu D, Zhu Z (2022) TRPC5 deletion in the central amygdala antagonizes high-fat diet-induced obesity by increasing sympathetic innervation. https://doi.org/10.1038/s41366-022-01151-xMouseFat
Weiss 2022 J Cell Mol Med2022Weiss SL, Zhang D, Farooqi S, Wallace DC (2022) Sodium butyrate reverses lipopolysaccharide-induced mitochondrial dysfunction in lymphoblasts. https://doi.org/10.1111/jcmm.17342Other cell lines
Kataura 2022 Dev Cell2022Kataura T, Sedlackova L, Otten EG, Kumari R, Shapira D, Scialo F, Stefanatos R, Ishikawa KI, Kelly G, Seranova E, Sun C, Maetzel D, Kenneth N, Trushin S, Zhang T, Trushina E, Bascom CC, Tasseff R, Isfort RJ, Oblong JE, Miwa S, Lazarou M, Jaenisch R, Imoto M, Saiki S, Papamichos-Chronakis M, Manjithaya R, Maddocks ODK, Sanz A, Sarkar S, Korolchuk VI (2022) Autophagy promotes cell survival by maintaining NAD levels. https://doi.org/10.1016/j.devcel.2022.10.008MouseFibroblast
Lebenzon 2022 Proc Natl Acad Sci U S A2022Lebenzon JE, Denezis PW, Mohammad L, Mathers KE, Turnbull KF, Staples JF, Sinclair BJ (2022) Reversible mitophagy drives metabolic suppression in diapausing beetles. Proc Natl Acad Sci U S A 119:e2201089119. https://doi.org/10.1073/pnas.2201089119HexapodsSkeletal muscle
Kleinwaechter 2022 RSC Chem Biol2022Kleinwaechter I, Mohr B, Joppe A, Hellmann N, Bereau T, Osiewacz HD, Schneider D (2022) CLiB - a novel cardiolipin-binder isolated via data-driven and in vitro screening. RSC Chem Biol 3:941-54. https://doi.org/10.1039/d2cb00125jFungi
Patyal 2022 Int J Mol Sci2022Patyal P, Nguyen B, Zhang X, Azhar G, Ameer FS, Verma A, Crane J, Kc G, Che Y, Wei JY (2022) Rho/SRF inhibitor modulates mitochondrial functions. https://doi.org/10.3390/ijms231911536MouseSkeletal muscle
Jayasankar 2022 ACS Omega2022Jayasankar V, Vrdoljak N, Roma A, Ahmed N, Tcheng M, Minden MD, Spagnuolo PA (2022) Novel mango ginger bioactive (2,4,6-trihydroxy-3,5-diprenyldihydrochalcone) inhibits mitochondrial metabolism in combination with Avocatin B. ACS Omega 7:1682-93. https://doi.org/10.1021/acsomega.1c04053
Weiss 2022 Shock2022Weiss SL, Henrickson SE, Lindell RB, Sartori LF, Zhang D, Bush J, Farooqi S, Starr J, Deutschman CS, McGowan FX Jr, Becker L, Tuluc F, Wherry EJ, Picard M, Wallace DC (2022) Influence of immune cell subtypes on mitochondrial measurements in peripheral blood mononuclear cells from children with sepsis. Shock 57:630-8. https://doi.org/10.1097/SHK.0000000000001903HumanBlood cells
Tang 2022 Elife2022Tang Y, Zong H, Kwon H, Qiu Y, Pessin JB, Wu L, Buddo KA, Boykov I, Schmidt CA, Lin CT, Neufer PD, Schwartz GJ, Kurland IJ, Pessin JE (2022) TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling. https://doi.org/10.7554/elife.73360MouseSkeletal muscle
Vandenberg 2022 Am J Physiol Cell Physiol2022Vandenberg GG, Thotakura A, Scott AL (2022) Mitochondrial bioenergetics of astrocytes in Fragile X syndrome: new perspectives on culture conditions and sex effects. Am J Physiol Cell Physiol 322:C125-35. https://doi.org/10.1152/ajpcell.00130.2021MouseNervous system
Simon 2022 Function (Oxf)2022Simon L, Molina PE (2022) Cellular bioenergetics: experimental evidence for alcohol-induced adaptations. Function (Oxf) 3:zqac039. https://doi.org/10.1093/function/zqac039
Timon-Gomez 2022 Elife2022Timón-Gómez A, Scharr AL, Wong NY, Ni E, Roy A, Liu M, Chau J, Lampert JL, Hireed H, Kim NS, Jan M, Gupta AR, Day RW, Gardner JM, Wilson RJA, Barrientos A, Chang AJ (2022) Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors. https://doi.org/10.7554/elife.78915
Siow 2022 J Cell Sci2022Siow WX, Kabiri Y, Tang R, Chao YK, Plesch E, Eberhagen C, Flenkenthaler F, Fröhlich T, Bracher F, Grimm C, Biel M, Zischka H, Vollmar AM, Bartel K (2022) Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells. https://doi.org/10.1242/jcs.259455MouseLiver
Barath 2022 Int J Mol Sci2022Baráth B, Jász DK, Horváth T, Baráth B, Maróti G, Strifler G, Varga G, Sándor L, Perényi D, Tallósy S, Donka T, Jávor P, Boros M, Hartmann P (2022) Mitochondrial side effects of surgical prophylactic antibiotics Ceftriaxone and Rifaximin lead to bowel mucosal damage. Int J Mol Sci 23:5064. https://doi.org/10.3390/ijms23095064RatLiver
Lehto 2022 Neurochem Res2022Lehto A, Koch K, Barnstorf-Brandes J, Viel C, Fuchs M, Klein J (2022) ß-Hydroxybutyrate improves mitochondrial function after transient ischemia in the mouse. https://doi.org/10.1007/s11064-022-03637-6MouseNervous system
Neupane 2022 Commun Biol2022Neupane N, Rajendran J, Kvist J, Harjuhaahto S, Hu B, Kinnunen V, Yang Y, Nieminen AI, Tyynismaa H (2022) Inter-organellar and systemic responses to impaired mitochondrial matrix protein import in skeletal muscle. https://doi.org/10.1038/s42003-022-04034-zMouseSkeletal muscle
Bresciani 2022 J Hepatol2022Bresciani N, Demagny H, Lemos V, Pontanari F, Li X, Sun Y, Li H, Perino A, Auwerx J, Schoonjans K (2022) The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosis. https://doi.org/10.1016/j.jhep.2022.05.040MouseLiver
Meza-Buendia 2022 PLoS One2022Meza-Buendia AK, Aparicio-Trejo OE, Díaz F, Caamal-Monsreal C, Pedraza-Chaverri J, Álvarez-Delgado C, Paschke K, Rosas C (2022) High resolution respirometry of isolated mitochondria from adult Octopus maya (Class: Cephalopoda) systemic heart. https://doi.org/10.1371/journal.pone.0273554MolluscsHeart
Fernandez-Vizarra 2022 Cell Metab2022Fernández-Vizarra E, López-Calcerrada S, Sierra-Magro A, Pérez-Pérez R, Formosa LE, Hock DH, Illescas M, Peñas A, Brischigliaro M, Ding S, Fearnley IM, Tzoulis C, Pitceathly RDS, Arenas J, Martín MA, Stroud DA, Zeviani M, Ryan MT, Ugalde C (2022) Two independent respiratory chains adapt OXPHOS performance to glycolytic switch. https://doi.org/10.1016/j.cmet.2022.09.005HumanHEK
Hamann 2022 J Fungi (Basel)2022Hamann A, Osiewacz HD, Teichert I (2022) Sordaria macrospora sterile mutant pro34 is impaired in respiratory complex I assembly. https://doi.org/10.3390/jof8101015Fungi
Quemeneur 2022 Sci Rep2022Quéméneur JB, Danion M, Cabon J, Collet S, Zambonino-Infante JL, Salin K (2022) The relationships between growth rate and mitochondrial metabolism varies over time. Sci Rep 12:16066. https://doi.org/10.1038/s41598-022-20428-9FishesSkeletal muscle
Kampa 2022 Antioxidants (Basel)2022Kampa RP, Flori L, Sęk A, Spezzini J, Brogi S, Szewczyk A, Calderone V, Bednarczyk P, Testai L (2022) Luteolin-induced activation of mitochondrial BKCa channels: undisclosed mechanism of cytoprotection. https://doi.org/10.3390/antiox11101892HumanEndothelial;epithelial;mesothelial cell
Wang 2022 Redox Biol2022Wang P, Cui Y, Liu Y, Li Z, Bai H, Zhao Y, Chang YZ (2022) Mitochondrial ferritin alleviates apoptosis by enhancing mitochondrial bioenergetics and stimulating glucose metabolism in cerebral ischemia reperfusion. https://doi.org/10.1016/j.redox.2022.102475MouseNervous system
Sleda 2022 mBio2022Sleda MA, Li ZH, Behera R, Baierna B, Li C, Jumpathong J, Malwal SR, Kawamukai M, Oldfield E, Moreno SNJ (2022) The heptaprenyl diphosphate synthase (Coq1) is the target of a lipophilic bisphosphonate that protects mice against toxoplasma gondii infection. https://doi.org/10.1128/mbio.01966-22Protists
Fuertes-Agudo 2022 Antioxidants (Basel)2022Fuertes-Agudo M, Luque-Tévar M, Cucarella C, Brea R, Boscá L, Quintana-Cabrera R, Martín-Sanz P, Casado M (2022) COX-2 expression in hepatocytes improves mitochondrial function after hepatic ischemia-reperfusion injury.MouseLiver
Saraiva 2022 Pathogens2022Saraiva FMS, Cosentino-Gomes D, Inacio JDF, Almeida-Amaral EE, Louzada-Neto O, Rossini A, Nogueira NP, Meyer-Fernandes JR, Paes MC (2022) Hypoxia effects on Trypanosoma cruzi epimastigotes proliferation, differentiation, and energy metabolism. https://doi.org/10.3390/pathogens11080897Protists
De Paula Nascimento-Castro 2022 Biomedicines2022de Paula Nascimento-Castro C, Winkelmann-Duarte EC, Mancini G, Welter PG, Plácido E, Farina M, Gil-Mohapel J, Rodrigues ALS, de Bem AF, Brocardo PS (2022) Temporal characterization of behavioral and hippocampal dysfunction in the YAC128 mouse model of Huntington's disease. https://doi.org/10.3390/biomedicines10061433MouseNervous system
Vanweert 2022 Nat Commun2022Vanweert F, Neinast M, Tapia EE, van de Weijer T, Hoeks J, Schrauwen-Hinderling VB, Blair MC, Bornstein MR, Hesselink MKC, Schrauwen P, Arany Z, Phielix E (2022) A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes. https://doi.org/10.1038/s41467-022-31249-9HumanSkeletal muscle
Risiglione 2022 Life (Basel)2022Risiglione P, Cubisino SAM, Lipari CLR, De Pinto V, Messina A, Magrì A (2022) α-Synuclein A53T promotes mitochondrial proton gradient dissipation and depletion of the organelle respiratory reserve in a neuroblastoma cell line. https://doi.org/10.3390/life12060894HumanNeuroblastoma
Roy 2022 Am J Pathol2022Roy N, Alencastro F, Roseman BA, Wilson SR, Delgado ER, May MC, Bhushan B, Bello FM, Jurczak MJ, Shiva S, Locker J, Gingras S, Duncan AW (2022) Dysregulation of lipid and glucose homeostasis in hepatocyte-specific SLC25A34 knockout mice. https://doi.org/10.1016/j.ajpath.2022.06.002MouseLiver
Munro 2022 Mitochondrion2022Munro D, Rodríguez E, Blier PU (2022) The longest-lived metazoan, Arctica islandica, exhibits high mitochondrial H2O2 removal capacities. Mitochondrion 68:81-86. https://doi.org/10.1016/j.mito.2022.11.005MolluscsLung;gill
Endothelial;epithelial;mesothelial cell
Neu 2022 BMJ Open2022Neu C, Skitek K, Kissler H, Baumbach P, Settmacher U, Esper Treml R, Coldewey SM (2022) Body composition, mitochondrial oxygen metabolism and metabolome of patients with obesity before and after bariatric surgery (COMMITMENT): protocol for a monocentric prospective cohort study. https://doi.org/10.1136/bmjopen-2022-062592HumanSkeletal muscle
Pochakom 2022 Brain Sci2022Pochakom A, Mu C, Rho JM, Tompkins TA, Mayengbam S, Shearer J (2022) Selective probiotic treatment positively modulates the microbiota-gut-brain axis in the BTBR mouse model of autism. https://doi.org/10.3390/brainsci12060781MouseNervous system
Brun 2022 Plant Direct2022Brun A, Smokvarska M, Wei L, Chay S, Curie C, Mari S (2022) MCO1 and MCO3, two putative ascorbate oxidases with ferroxidase activity, new candidates for the regulation of apoplastic iron excess in Arabidopsis. https://doi.org/10.1002/pld3.463Saccharomyces cerevisiae
Dias 2022 Free Radic Biol Med2022Dias C, Lourenço CF, Laranjinha J, Ledo A (2022) Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite. https://doi.org/10.1016/j.freeradbiomed.2022.11.021RatNervous system
Fedorov 2022 Naunyn Schmiedebergs Arch Pharmacol2022Fedorov A, Lehto A, Klein J (2022) Inhibition of mitochondrial respiration by general anesthetic drugs. https://doi.org/10.1007/s00210-022-02338-9MouseNervous system
Dawson 2022 FASEB J2022Dawson NJ, Scott GR (2022) Adaptive increases in respiratory capacity and O2 affinity of subsarcolemmal mitochondria from skeletal muscle of high-altitude deer mice. https://doi.org/10.1096/fj.202200219rMouseSkeletal muscle
Davies 2022 Biomolecules2022Davies KL, Smith DJ, El-Bacha T, Wooding PFP, Forhead AJ, Murray AJ, Fowden AL, Camm EJ (2022) Cortisol regulates cerebral mitochondrial oxidative phosphorylation and morphology of the brain in a region-specific manner in the ovine fetus. https://doi.org/10.3390/biom12060768Other mammalsNervous system
Quast 2022 Basic Res Cardiol2022Quast C, Kober F, Becker K, Zweck E, Hoffe J, Jacoby C, Flocke V, Gyamfi-Poku I, Keyser F, Piayda K, Erkens R, Niepmann S, Adam M, Baldus S, Zimmer S, Nickenig G, Grandoch M, Bönner F, Kelm M, Flögel U (2022) Multiparametric MRI identifies subtle adaptations for demarcation of disease transition in murine aortic valve stenosis. https://doi.org/10.1007/s00395-022-00936-5MouseHeart
Pedersen 2022 Nat Commun2022Pedersen JS, Rygg MO, Chrøis K, Sustarsic EG, Gerhart-Hines Z, Wever Albrechtsen NJ, Serizawa RR, Kristiansen VB, Basse AL, Boilesen AEB, Olsen BH, Hansen T, Gluud LL, Madsbad S, Larsen S, Bendtsen F, Dela F (2022) Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration. Nat Commun 13:2931. https://doi.org/10.1038/s41467-022-30629-5HumanLiver
Fat
Graham 2022 Physiol Rep2022Graham ZA, DeBerry JJ, Cardozo CP, Bamman MM (2022) SS-31 does not prevent or reduce muscle atrophy 7 days after a 65 kdyne contusion spinal cord injury in young male mice. https://doi.org/10.14814/phy2.15266MouseSkeletal muscle
Sautchuk 2022 Bone Rep2022Sautchuk R Jr, Eliseev RA (2022) Cell energy metabolism and bone formation. https://doi.org/10.1016/j.bonr.2022.101594
Mendes 2022 Mitochondrion2022Mendes D, Peixoto F, Oliveira MM, Andrade PB, Videira RA (2022) Mitochondria research and neurodegenerative diseases: On the track to understanding the biological world of high complexity. https://doi.org/10.1016/j.mito.2022.05.001
Halbrook 2022 Nat Cancer2022Halbrook CJ, Thurston G, Boyer S, Anaraki C, Jiménez JA, McCarthy A, Steele NG, Kerk SA, Hong HS, Lin L, Law FV, Felton C, Scipioni L, Sajjakulnukit P, Andren A, Beutel AK, Singh R, Nelson BS, Van Den Bergh F, Krall AS, Mullen PJ, Zhang L, Batra S, Morton JP, Stanger BZ, Christofk HR, Digman MA, Beard DA, Viale A, Zhang J, Crawford HC, Pasca di Magliano M, Jorgensen C, Lyssiotis CA (2022) Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells. https://doi.org/10.1038/s43018-022-00463-1
Napso 2022 Acta Physiol (Oxf)2022Napso T, Lean SC, Lu M, Mort EJ, Desforges M, Moghimi A, Bartels B, El-Bacha T, Fowden AL, Camm EJ, Sferruzzi-Perri AN (2022) Diet-induced maternal obesity impacts feto-placental growth and induces sex-specific alterations in placental morphology, mitochondrial bioenergetics, dynamics, lipid metabolism and oxidative stress in mice. https://doi.org/10.1111/apha.13795MouseGenital
Antona 2022 Cancers (Basel)2022Antona A, Varalda M, Roy K, Favero F, Mazzucco E, Zuccalà M, Leo G, Soggia G, Bettio V, Tosi M, Gaggianesi M, Riva B, Reano S, Genazzani A, Manfredi M, Stassi G, Corà D, D'Alfonso S, Capello D (2022) Dissecting the mechanism of action of spiperone-a candidate for drug repurposing for colorectal cancer. https://doi.org/10.3390/cancers14030776HumanEndothelial;epithelial;mesothelial cell
Damgaard 2022 iScience2022Damgaard MV, Nielsen TS, Basse AL, Chubanava S, Trost K, Moritz T, Dellinger RW, Larsen S, Treebak JT (2022) Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity. iScience 25:103863. https://doi.org/10.1016/j.isci.2022.103863MouseSkeletal muscle
Harris 2022 Autophagy2022Harris MP, Zhang QJ, Cochran CT, Ponce J, Alexander S, Kronemberger A, Fuqua JD, Zhang Y, Fattal R, Harper T, Murry ML, Grueter CE, Abel ED, Lira VA (2022) Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function. https://doi.org/10.1080/15548627.2021.2022289MouseHeart
Lopes 2022 Int J Mol Sci2022Lopes JA, Collino F, Rodrigues-Ferreira C, Sampaio LDS, Costa-Sarmento G, Wendt CHC, Almeida FP, Miranda KR, Kasai-Brunswick TH, Lindoso RS, Vieyra A (2022) Early effects of extracellular vesicles secreted by adipose tissue mesenchymal cells in renal ischemia followed by reperfusion: mechanisms rely on a decrease in mitochondrial anion superoxide production. Int J Mol Sci 23:2906. https://doi.org/10.3390/ijms23062906HumanKidney
Pinho 2022 Antioxidants (Basel)2022Pinho N, Bombaça AC, Wiśniewski JR, Dias-Lopes G, Saboia-Vahia L, Cupolillo E, de Jesus JB, de Almeida RP, Padrón G, Menna-Barreto R, Cuervo P (2022) Nitric oxide resistance in Leishmania (Viannia) braziliensis involves regulation of glucose consumption, glutathione metabolism and abundance of pentose phosphate pathway enzymes. https://doi.org/10.3390/antiox11020277Protists
Zhao 2022 J Cell Sci2022Zhao Q, Yan S, Lu J, Parker DJ, Wu H, Sun Q, Crossman DK, Liu S, Wang Q, Sesaki H, Mitra K, Liu K, Jiao K (2022) Drp1 regulates transcription of ribosomal protein genes in embryonic hearts. https://doi.org/10.1242/jcs.258956MouseHeart
Hegazy 2022 Biomedicines2022Hegazy L, Gill LE, Pyles KD, Kaiho C, Kchouk S, Finck BN, McCommis KS, Elgendy B (2022) Identification of novel mitochondrial pyruvate carrier inhibitors by homology modeling and pharmacophore-based virtual screening. https://doi.org/10.3390/biomedicines10020365MouseHeart
Rome 2022 Mol Metab2022Rome FI, Hughey CC (2022) Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction. https://doi.org/10.1016/j.molmet.2022.101452MouseLiver
Gomez 2022 Nutrients2022Gómez Rodríguez A, Talamonti E, Naudi A, Kalinovich AV, Pauter AM, Barja G, Bengtsson T, Jacobsson A, Pamplona R, Shabalina IG (2022) Elovl2-ablation leads to mitochondrial membrane fatty acid remodeling and reduced efficiency in mouse liver mitochondria. https://doi.org/10.3390/nu14030559MouseLiver
Evinova 2022 Mol Cell Biochem2022Evinova A, Hatokova Z, Tatarkova Z, Brodnanova M, Dibdiakova K, Racay P (2022) Endoplasmic reticulum stress induces mitochondrial dysfunction but not mitochondrial unfolded protein response in SH-SY5Y cells. https://doi.org/10.1007/s11010-021-04344-6
Mahalaxmi 2022 Toxicol In Vitro2022Mahalaxmi G, Ashok S, Arun G, Srinivas G (2022) Albumin binds to uncoupler CCCP to diminish depolarization of mitochondria. https://doi.org/10.1016/j.tiv.2022.105325
Olesen 2022 Metabol Open2022Olesen K, Moruzzi N, Bulatovic I, Folmes C, Jeon R, Felldin U, Terzic A, Simonson OE, Le Blanc K, Österholm C, Berggren PO, Schiffer T, Rodin S, Tilevik A, Grinnemo KH (2022) Diversity of respiratory parameters and metabolic adaptation to low oxygen tension in mesenchymal stromal cells. https://doi.org/10.1016/j.metop.2022.100167HumanOther cell lines
Muccini 2022 Oxid Med Cell Longev2022Muccini AM, Tran NT, Hale N, McKenzie M, Snow RJ, Walker DW, Ellery SJ (2022) The effects of in utero fetal hypoxia and creatine treatment on mitochondrial function in the late gestation fetal sheep brain. https://doi.org/10.1155/2022/3255296Other mammalsNervous system
Broome 2022 Redox Biol2022Broome SC, Pham T, Braakhuis AJ, Narang R, Wang HW, Hickey AJR, Mitchell CJ, Merry TL (2022) MitoQ supplementation augments acute exercise-induced increases in muscle PGC1α mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men. https://doi.org/10.1016/j.redox.2022.102341HumanSkeletal muscle
Salyers 2022 JVS Vasc Sci2022Salyers ZR, Mariani V, Balestrieri N, Kumar RA, Vugman NA, Thome T, Villani KR, Berceli SA, Scali ST, Vasilakos G, Ryan TE (2022) S100A8 and S100A9 are elevated in chronically threatened ischemic limb muscle and induce ischemic mitochondrial pathology in mice. https://doi.org/10.1016/j.jvssci.2022.03.003Human
Mouse
Skeletal muscle
Gentile 2022 FASEB J2022Gentile A, Magnacca N, de Matteis R, Moreno M, Cioffi F, Giacco A, Lanni A, de Lange P, Senese R, Goglia F, Silvestri E, Lombardi A (2022) Ablation of uncoupling protein 3 affects interrelated factors leading to lipolysis and insulin resistance in visceral white adipose tissue. https://doi.org/10.1096/fj.202101816rrMouseFat
Froment 2022 Hum Reprod2022Froment P, Plotton I, Giulivi C, Fabre S, Khoueiry R, Mourad NI, Horman S, Ramé C, Rouillon C, Grandhaye J, Bigot Y, Chevaleyre C, Le Guevel R, Mallegol P, Andriantsitohaina R, Guerif F, Tamburini J, Viollet B, Foretz M, Dupont J (2022) At the crossroads of fertility and metabolism: the importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism. https://doi.org/10.1093/humrep/deac067
Erdem 2022 Nat Commun2022Erdem A, Marin S, Pereira-Martins DA, Geugien M, Cunningham A, Pruis MG, Weinhäuser I, Gerding A, Bakker BM, Wierenga ATJ, Rego EM, Huls G, Cascante M, Schuringa JJ (2022) Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability. https://doi.org/10.1038/s41467-022-29639-0HumanOther cell lines
Greenwood 2022 BMC Nephrol2022Greenwood SA, Beckley-Hoelscher N, Asgari E, Ayis S, Baker LA, Banerjee D, Bhandari S, Bramham K, Chilcot J, Burton J, Kalra PA, Lightfoot CJ, McCafferty K, Mercer TH, Okonko DO, Oliveira B, Reid C, Smith AC, Swift PA, Mangelis A, Watson E, Wheeler DC, Wilkinson TJ, Reid F, Macdougall IC (2022) The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a multicentre prospective double-blind randomised controlled trial. https://doi.org/10.1186/s12882-022-02896-3HumanSkeletal muscle
Melin 2022 JHEP Rep2022Melin N, Yarahmadov T, Sanchez-Taltavull D, Birrer FE, Brodie TM, Petit B, Felser A, Nuoffer JM, Montani M, Vozenin MC, Herrmann E, Candinas D, Aebersold DM, Stroka D (2022) A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus. https://doi.org/10.1016/j.jhepr.2022.100508MouseLiver
Hansen 2022 Magn Reson Med2022Hansen K, Hansen ESS, Jespersen NRV, Bøtker HE, Pedersen M, Wang T, Laustsen C (2022) Hyperpolarized 13C MRI reveals large changes in pyruvate metabolism during digestion in snakes. https://doi.org/10.1002/mrm.29239ReptilesLiver
Jardim-Messeder 2022 Biochim Biophys Acta Bioenerg2022Jardim-Messeder D, Margis-Pinheiro M, Sachetto-Martins G (2022) Salicylic acid and adenine nucleotides regulate the electron transport system and ROS production in plant mitochondria. https://doi.org/10.1016/j.bbabio.2022.148559
Della Noce 2022 J Biol Chem2022Della Noce B, Martins da Silva R, de Carvalho Uhl MV, Konnai S, Ohashi K, Calixto C, Arcanjo A, de Abreu LA, de Carvalho SS, da Silva Vaz I Jr, Logullo C (2022) Redox imbalance induces remodeling of glucose metabolism in Rhipicephalus microplus embryonic cell line. https://doi.org/10.1016/j.jbc.2022.101599CheliceratesOther cell lines
Komlodi 2022 BEC2022Komlódi T, Tretter L (2022) The protonmotive force – not merely membrane potential. Bioenerg Commun 2022.16. https://doi.org/10.26124/bec:2022-0016
Zhou 2022 J Hum Genet2022Zhou X, Lou X, Zhou Y, Xie Y, Han X, Dong Q, Ying X, Laurentinah MR, Zhang L, Chen Z, Li D, Fang H, Lyu J, Yang Y, Wang Y (2022) Novel biallelic mutations in TMEM126B cause splicing defects and lead to Leigh-like syndrome with severe complex I deficiency. https://doi.org/10.1038/s10038-022-01102-4HumanLymphocyte
Turton 2022 Int J Mol Sci2022Turton N, Cufflin N, Dewsbury M, Fitzpatrick O, Islam R, Watler LL, McPartland C, Whitelaw S, Connor C, Morris C, Fang J, Gartland O, Holt L, Hargreaves IP (2022) The biochemical assessment of mitochondrial respiratory chain disorders. Int J Mol Sci 23:7487. https://doi.org/10.3390/ijms23137487Human
Wagner 2022 J Muscle Res Cell Motil2022Wagner PD (2022) Determinants of maximal oxygen consumption. https://doi.org/10.1007/s10974-022-09636-y
Lemminger 2022 Antioxidants (Basel)2022Lemminger AK, Fiorenza M, Eibye K, Bangsbo J, Hostrup M (2022) High-intensity exercise training alters the effect of N-acetylcysteine on exercise-related muscle ionic shifts in men. https://doi.org/10.3390/antiox12010053HumanSkeletal muscle
Cruz-Gregorio 2022 Antioxidants (Basel)2022Cruz-Gregorio A, Aranda-Rivera AK, Aparicio-Trejo OE, Medina-Campos ON, Sciutto E, Fragoso G, Pedraza-Chaverri J (2022) GK-1 Induces oxidative stress, mitochondrial dysfunction, decreased membrane potential, and impaired autophagy flux in a mouse model of breast cancer. Antioxidants (Basel) 12:56. https://doi.org/10.3390/antiox12010056MouseEndothelial;epithelial;mesothelial cell
Jedlicka 2022a Physiol Res2022Jedlička J, Tůma Z, Razak K, Kunc R, Kala A, Proskauer Pena S, Lerchner T, Ježek K, Kuncová J (2022) Impact of aging on mitochondrial respiration in various organs. https://doi.org/10.33549/physiolres.934995RatHeart
Skeletal muscle
Nervous system
Liver
Kidney
Platelet
Jedlicka 2022 Physiol Res2022Jedlička J, Grundmanová M, Švíglerová J, Tůma Z, Nalos L, Rajdl D, Štengl M, Kuncová J (2022) Mitochondrial dysfunction in kidney cortex and medulla of subtotally nephrectomized rats. Physiol Res 71:S219-26. https://doi.org/10.33549/physiolres.935000RatKidney
Lu 2022 J Cosmet Dermatol2022Lu Q, Zou LF, Gao YZ, Ye T, Li MJ, Zhang YK, Liang B, Sun W, Xing DM (2022) Liquiritigenin reverses skin aging by inhibiting UV-induced mitochondrial uncoupling and excessive energy consumption. https://doi.org/10.1111/jocd.15506HumanEndothelial;epithelial;mesothelial cell
Galambo 2022 Curr Res Physiol2022Galambo D, Bergdahl A (2022) Physiological levels of cardiolipin acutely affect mitochondrial respiration in vascular smooth muscle cells. https://doi.org/10.1016/j.crphys.2022.100097MouseOther cell lines
Vera-Vives 2022 BEC2022Vera-Vives AM, Perin G, Morosinotto T (2022) High-resolution photosynthesis-irradiance curves in microalgae. Bioenerg Commun 2022.19. https://doi.org/10.26124/bec:2022-0019Algae
Horvath 2022 Antioxidants (Basel)2022Horváth G, Sváb G, Komlódi T, Ravasz D, Kacsó G, Doczi J, Chinopoulos C, Ambrus A, Tretter L (2022) Reverse and forward electron flow-induced H2O2 formation is decreased in α-ketoglutarate dehydrogenase (α-KGDH) subunit (E2 or E3) heterozygote knock out animals. https://doi.org/10.3390/antiox11081487MouseNervous system
Englund 2022 Mol Metab2022Englund DA, Jolliffe A, Aversa Z, Zhang X, Sturmlechner I, Sakamoto AE, Zeidler JD, Warner GM, McNinch C, White TA, Chini EN, Baker DJ, van Deursen JM, LeBrasseur NK (2022) p21 induces a senescence program and skeletal muscle dysfunction. https://doi.org/10.1016/j.molmet.2022.101652MouseSkeletal muscle
Tomar 2022 Biochim Biophys Acta Bioenerg2022Tomar N, Zhang X, Kandel SM, Sadri S, Yang C, Liang M, Audi SH, Cowley AW Jr, Dash RK (2022) Substrate-dependent differential regulation of mitochondrial bioenergetics in the heart and kidney cortex and outer medulla. https://doi.org/10.1016/j.bbabio.2021.148518RatHeart
Kidney
Hansen 2022 Free Radic Biol Med2022Hansen C, Møller S, Ehlers T, Wickham KA, Bangsbo J, Gliemann L, Hellsten Y (2022) Redox balance in human skeletal muscle-derived endothelial cells - Effect of exercise training. Free Radic Biol Med 179:144-55. https://doi.org/10.1016/j.freeradbiomed.2021.12.265HumanEndothelial;epithelial;mesothelial cell
Sumbalova 2022 Front Mol Biosci2022Sumbalová Z, Kucharská J, Rausová Z, Palacka P, Kovalčíková E, Takácsová T, Mojto V, Navas P, Lopéz-Lluch G, Gvozdjáková A (2022) Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. https://doi.org/10.3389/fmolb.2022.1016352HumanPlatelet
De Lazzari 2022 Neurobiol Dis2022De Lazzari F, Agostini F, Plotegher N, Sandre M, Greggio E, Megighian A, Bubacco L, Sandrelli F, Whitworth AJ, Bisaglia M (2022) DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis. https://doi.org/10.1016/j.nbd.2022.105941Drosophila
Zhang 2022 Mol Med Rep2022Zhang J, Sun B, Yang J, Chen Z, Li Z, Zhang N, Li H, Shen L (2022) Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models. https://doi.org/10.3892/mmr.2022.12607MouseNervous system
De Jong 2022 Nutrients2022De Jong NP, Rudolph MC, Jackman MR, Sharp RR, Jones K, Houck J, Pan Z, Reusch JEB, MacLean PS, Bessesen DH, Bergouignan A (2022) Short-term adaptations in skeletal muscle mitochondrial oxidative capacity and metabolic pathways to breaking up sedentary behaviors in overweight or obese adults. https://doi.org/10.3390/nu14030454HumanSkeletal muscle
Ryan 2022 Clin Transl Med2022Ryan TE, Kim K, Scali ST, Berceli SA, Thome T, Salyers ZR, O'Malley KA, Green TD, Karnekar R, Fisher-Wellman KH, Yamaguchi DJ, McClung JM (2022) Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb. https://doi.org/10.1002/ctm2.658HumanSkeletal muscle
Triolo 2022 J Physiol2022Triolo M, Slavin M, Moradi N, Hood DA (2022) Time-dependent changes in autophagy, mitophagy and lysosomes in skeletal muscle during denervation-induced disuse. https://doi.org/10.1113/jp282173
Qvit 2022 Pharmaceuticals (Basel)2022Qvit N, Lin AJ, Elezaby A, Ostberg NP, Campos JC, Ferreira JCB, Mochly-Rosen D (2022) A selective inhibitor of cardiac troponin I phosphorylation by delta protein kinase C (δPKC) as a treatment for ischemia-reperfusion injury. Pharmaceuticals (Basel) 15:271. https://doi.org/10.3390/ph15030271RatHeart
Chojnacka 2022 Mol Biol Cell2022Chojnacka KJ, Elancheliyan P, Mussulini BHM, Mohanraj K, Callegari S, Gosk A, Banach T, Góral T, Szczepanowska K, Rehling P, Serwa RA, Chacinska A (2022) Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III-specific assembly factor in mitochondria. https://doi.org/10.1091/mbc.e21-03-0143HumanHEK
Heher 2022 Redox Biol2022Heher P, Ganassi M, Weidinger A, Engquist EN, Pruller J, Nguyen TH, Tassin A, Declèves AE, Mamchaoui K, Banerji CRS, Grillari J, Kozlov AV, Zammit PS (2022) Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target. https://doi.org/10.1016/j.redox.2022.102251HumanSkeletal muscle
Markovic 2022 Biomedicines2022Marković A, Tauchmannová K, Šimáková M, Mlejnek P, Kaplanová V, Pecina P, Pecinová A, Papoušek F, Liška F, Šilhavý J, Mikešová J, Neckář J, Houštěk J, Pravenec M, Mráček T (2022) Genetic complementation of ATP synthase deficiency due to dysfunction of TMEM70 assembly factor in rat. https://doi.org/10.3390/biomedicines10020276RatHeart
Liver
De Goede 2022 FASEB J2022de Goede P, Wüst RCI, Schomakers BV, Denis S, Vaz FM, Pras-Raves ML, van Weeghel M, Yi CX, Kalsbeek A, Houtkooper RH (2022) Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle. FASEB J 36:e22133.RatSkeletal muscle
Thapa 2022 Physiol Rep2022Thapa D, Bugga P, Mushala BAS, Manning JR, Stoner MW, McMahon B, Zeng X, Cantrell PS, Yates N, Xie B, Edmunds LR, Jurczak MJ, Scott I (2022) GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation. https://doi.org/10.14814/phy2.15415MouseHeart
Tepp 2022 Biochem Biophys Rep2022Tepp K, Aid-Vanakova J, Puurand M, Timohhina N, Reinsalu L, Tein K, Plaas M, Shevchuk I, Terasmaa A, Kaambre T (2022) Wolframin deficiency is accompanied with metabolic inflexibility in rat striated muscles. Biochem Biophys Rep 30:101250.RatSkeletal muscle
Fischer 2022 Metabolites2022Fischer C, Valente de Souza L, Komlódi T, Garcia-Souza LF, Volani C, Tymoszuk P, Demetz E, Seifert M, Auer K, Hilbe R, Brigo N, Petzer V, Asshoff M, Gnaiger E, Weiss G (2022) Mitochondrial respiration in response to iron deficiency anemia. Comparison of peripheral blood mononuclear cells and liver. Metabolites 12:270. https://doi.org/10.3390/metabo12030270RatLiver
Blood cells
Adant 2022 Mol Metab2022Adant I, Bird M, Decru B, Windmolders P, Wallays M, de Witte P, Rymen D, Witters P, Vermeersch P, Cassiman D, Ghesquière B (2022) Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction. https://doi.org/10.1016/j.molmet.2022.101537HumanFibroblast
Nath 2022 Cell Rep2022Nath AS, Parsons BD, Makdissi S, Chilvers RL, Mu Y, Weaver CM, Euodia I, Fitze KA, Long J, Scur M, Mackenzie DP, Makrigiannis AP, Pichaud N, Boudreau LH, Simmonds AJ, Webber CA, Derfalvi B, Hammon Y, Rachubinski RA, Di Cara F (2022) Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses . Cell Rep 38:110433.
Pileggi 2022 EBioMedicine2022Pileggi CA, Blondin DP, Hooks BG, Parmar G, Alecu I, Patten DA, Cuillerier A, O'Dwyer C, Thrush AB, Fullerton MD, Bennett SAL, Doucet É, Haman F, Cuperlovic-Culf M, McPherson R, Dent RRM, Harper ME (2022) Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity. EBioMedicine 83:104192. https://doi.org/10.1016/j.ebiom.2022.104192HumanSkeletal muscle
Molinie 2022 Biochim Biophys Acta Bioenerg2022Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532.MouseHeart
Liver
Zdrazilova 2022 PLOS ONE2022Zdrazilova L, Hansikova H, Gnaiger E (2022) Comparable respiratory activity in attached and suspended human fibroblasts. PLoS ONE 17:e0264496. https://doi.org/10.1371/journal.pone.0264496HumanFibroblast
Bouitbir 2022 Int J Mol Sci2022Bouitbir J, Panajatovic MV, Krähenbühl S (2022) Mitochondrial toxicity associated with imatinib and sorafenib in isolated rat heart fibers and the cardiomyoblast H9c2 cell line. Int J Mol Sci 23:2282. https://doi.org/10.3390/ijms23042282RatHeart
Baglivo 2022 MitoFit-QC2022Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. https://doi.org/10.26124/mitofit:2022-0018.v22022-08-04 published in Bioenerg Commun 2022.8.HEK
Wang 2022 Transl Cancer Res2022Wang B, Liu B, Luo Q, Sun D, Li H, Zhang J, Jin X, Cheng X, Niu J, Yuan Q, Chen Y (2022) PANK1 associates with cancer metabolism and immune infiltration in clear cell renal cell carcinoma: a retrospective prognostic study based on the TCGA database. https://doi.org/10.21037/tcr-22-1488HumanKidney
Endothelial;epithelial;mesothelial cell
Lai 2022 PLoS One2022Lai RE, Holman ME, Chen Q, Rivers J, Lesnefsky EJ, Gorgey AS (2022) Assessment of mitochondrial respiratory capacity using minimally invasive and noninvasive techniques in persons with spinal cord injury. PLoS One 17:e0265141.Skeletal muscle
Ilha 2022 Cell Biol Int2022Ilha M, Meira Martins LA, da Silveira Moraes K, Dias CK, Thomé MP, Petry F, Rohden F, Borojevic R, Trindade VMT, Klamt F, Barbé-Tuana F, Lenz G, Guma FCR (2022) Caveolin-1 influences mitochondrial plasticity and function in hepatic stellate cell activation. https://doi.org/10.1002/cbin.11876MouseLiver
Li 2022 Hypertens Res2022Li L, Ma L, Luo Z, Wei X, Zhao Y, Zhou C, Mou A, Lu Z, You M, He C, Ma H, Zhou Q, Wang L, Cao T, Gu Y, Gao P, Zhu Z (2022) Lack of TRPV1 aggravates obesity-associated hypertension through the disturbance of mitochondrial Ca2+ homeostasis in brown adipose tissue. https://doi.org/10.1038/s41440-021-00842-8Mouse
Brunetta 2022 Redox Biol2022Brunetta HS, Petrick HL, Momken I, Handy RM, Pignanelli C, Nunes EA, Piquereau J, Mericskay M, Holloway GP (2022) Nitrate consumption preserves HFD-induced skeletal muscle mitochondrial ADP sensitivity and lysine acetylation: A potential role for SIRT1. https://doi.org/10.1016/j.redox.2022.102307MouseSkeletal muscle
Jelenik 2022 Pharmacol Res2022Jelenik T, Kodde A, Pesta D, Phielix E, Oosting A, Rohbeck E, Dewidar B, Mastrototaro L, Trenkamp S, Keijer J, van der Beek EM, Roden M (2022) Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming. Pharmacol Res 179:106193. https://doi.org/10.1016/j.phrs.2022.106193MouseSkeletal muscle
Liver
Pruett 2022 Biol Sex Differ2022Pruett JE, Everman SJ, Hoang NH, Salau F, Taylor LC, Edwards KS, Hosler JP, Huffman AM, Romero DG, Yanes Cardozo LL (2022) Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition. https://doi.org/10.1186/s13293-022-00455-xRatFat
Schober 2022 Hum Mol Genet2022Schober FA, Tang JX, Sergeant K, Moedas MF, Zierz CM, Moore D, Smith C, Lewis D, Guha N, Hopton S, Falkous G, Lam A, Pyle A, Poulton J, Gorman GS, Taylor RW, Freyer C, Wredenberg A (2022) Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease. https://doi.org/10.1093/hmg/ddac002Mouse
Drosophila
Fibroblast
Hadjihambi 2022 J Hepatol2022Hadjihambi A, Konstantinou C, Klohs J, Monsorno K, Le Guennec A, Donnelly C, Cox J, Kusumbe A, Hosford PS, Soffientini U, Lecca S, Mameli M, Jalan R, Paolicelli RC, Pellerin L (2022) Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction. https://doi.org/10.1016/j.jhep.2022.08.008MouseNervous system
Aya 2022 Eur J Pharmacol2022Shiraki A, Oyama J, Shimizu T, Nakajima T, Yokota T, Node K (2022) Empagliflozin improves cardiac mitochondrial function and survival through energy regulation in a murine model of heart failure. Eur J Pharmacol 931: 175194.MouseHeart
Daradics 2022 PLoS One2022Daradics N, Horvath G, Tretter L, Paal A, Fulop A, Budai A, Szijarto A (2022) The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy. https://doi.org/10.1371/journal.pone.0271606MouseLiver
Hong 2022 Cell Stem Cell2022Hong X, Isern J, Campanario S, Perdiguero E, Ramírez-Pardo I, Segalés J, Hernansanz-Agustín P, Curtabbi A, Deryagin O, Pollán A, González-Reyes JA, Villalba JM, Sandri M, Serrano AL, Enríquez JA, Muñoz-Cánoves P (2022) Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy. https://doi.org/10.1016/j.stem.2022.07.009MouseSkeletal muscle
Arbon 2022 Antimicrob Agents Chemother2022Arbon D, Ženíšková K, Šubrtová K, Mach J, Štursa J, Machado M, Zahedifard F, Leštinová T, Hierro-Yap C, Neuzil J, Volf P, Ganter M, Zoltner M, Zíková A, Werner L, Sutak R (2022) Repurposing of MitoTam: Novel anti-cancer drug candidate exhibits potent activity against major protozoan and fungal pathogens. https://doi.org/10.1128/aac.00727-22Protists
Heimler 2022 BEC2022Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2022) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. Bioenerg Commun 2022.2. https://doi.org/10.26124/bec:2022-0002HumanBlood cells
Karavyraki 2022 MitoFit2022Karavyraki M, Gnaiger E, Porter RK (2022) A comparison of bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells. https://doi.org/10.26124/mitofit:2022-00222022-11-11 published in Bioenerg Commun 2022.11.Human
Pallag 2022 Int J Mol Sci2022Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation supports mitochondrial ATP production when Complex I is inhibited. Int J Mol Sci 23:5111. https://doi.org/10.3390/ijms23095111MouseLiver
Kidney
Serna 2022 MitoFit2022Serna JDC, Ramos VM, Cabral-Costa JV, Vilas-Boas EA, Amaral AG, Ohya G, da Silva CCC, Kowaltowski AJ (2022) Measuring mitochondrial Ca2+ efflux in isolated mitochondria and permeabilized cells. https://doi.org/10.26124/mitofit:2022-00212022-07-28 published in Bioenerg Commun 2022.7.Human
Mouse
Liver
Other cell lines
Yamauchi 2022 Sci Rep2022Yamauchi Y, Nakamura A, Yokota T, Takahashi K, Kawata S, Tsuchida K, Omori K, Nomoto H, Kameda H, Cho KY, Anzai T, Tanaka S, Terauchi Y, Miyoshi H, Atsumi T (2022) Luseogliflozin preserves the pancreatic beta-cell mass and function in db/db mice by improving mitochondrial function. Sci Rep 12: 9740. https://doi.org/10.1038/s41598-022-13888-6MouseIslet cell;pancreas;thymus
Chicco 2022 MitoFit2022Chicco AJ, Zilhaver PT, Whitcomb LA, Fresa KJ, Izon CS, Gonzalez-Franquesa A, Izon CS, Dometita C, Irving BA, Garcia-Roves PM (2022) Resolving the Rotenone Paradox: elucidating the complexity of multi-substrate respirometry protocols. https://doi.org/10.26124/mitofit:2022-0017
Munoz-Pujol 2022 Brain Pathol2022Muñoz-Pujol G, Ortigoza-Escobar JD, Paredes-Fuentes AJ, Jou C, Ugarteburu O, Gort L, Yubero D, García-Cazorla A, O'Callaghan M, Campistol J, Muchart J, Yépez VA, Gusic M, Gagneur J, Prokisch H, Artuch R, Ribes A, Urreizti R, Tort F (2022) Leigh syndrome is the main clinical characteristic of PTCD3 deficiency. https://doi.org/10.1111/bpa.13134HumanFibroblast
Hernandez-Ainsa 2022 Dis Model Mech2022Hernández-Ainsa C, López-Gallardo E, García-Jiménez MC, Climent-Alcalá FJ, Rodríguez-Vigil C, García Fernández de Villalta M, Artuch R, Montoya J, Ruiz-Pesini E, Emperador (2022) Development and characterization of cell models harbouring mtDNA deletions for in vitro study of Pearson syndrome. Dis Model Mech 15:dmm049083.
Gancheva 2022 Diabetes Care2022Gancheva S, Kahl S, Pesta D, Mastrototaro L, Dewidar B, Strassburger K, Sabah E, Esposito I, Weiß J, Sarabhai T, Wolkersdorfer M, Fleming T, Nawroth P, Zimmermann M, Reichert AS, Schlensak M, Roden M (2022) Impaired hepatic mitochondrial capacity in nonalcoholic steatohepatitis associated with type 2 diabetes. https://doi.org/10.2337/dc21-1758Liver
Lang 2022 Cell Mol Life Sci2022Lang M, Grünewald A, Pramstaller PP, Hicks AA, Pichler I (2022) A genome on shaky ground: exploring the impact of mitochondrial DNA integrity on Parkinson's disease by highlighting the use of cybrid models. https://doi.org/10.1007/s00018-022-04304-3
Donnelly 2022 MitoFit Hypoxia2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v22022-11-14 published in Bioenerg Commun 2022.12.
Ahn 2022 Aging Cell2022Ahn B, Ranjit R, Kneis P, Xu H, Piekarz KM, Freeman WM, Kinter M, Richardson A, Ran Q, Brooks SV, Van Remmen H (2022) Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia. Aging Cell 21:e13569.MouseSkeletal muscle
Leggio 2022 Adv Healthc Mater2022Leggio L, L'Episcopo F, Magrì A, Ulloa-Navas MJ, Paternò G, Vivarelli S, Bastos CAP, Tirolo C, Testa N, Caniglia S, Risiglione P, Pappalardo F, Serra A, García-Tárraga P, Faria N, Powell JJ, Peruzzotti-Jametti L, Pluchino S, García-Verdugo JM, Messina A, Marchetti B, Iraci N (2022) Small extracellular vesicles secreted by nigrostriatal astrocytes rescue cell death and preserve mitochondrial function in Parkinson's disease. https://doi.org/10.1002/adhm.202201203HumanNeuroblastoma
Torres-Quesada 2022 MitoFit2022Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Human Plasma-Like Media fine-tune mitochondrial function and alter drug sensitivity in cancer cell lines. https://doi.org/10.26124/mitofit:2022-00082022-08-13 published in https://doi.org/10.3390/cancers14163917HumanOther cell lines
Goudie 2022 Sci Rep2022Goudie L, Mancini NL, Shutt TE, Holloway GP, Mu C, Wang A, McKay DM, Shearer J (2022) Impact of experimental colitis on mitochondrial bioenergetics in intestinal epithelial cells. https://doi.org/10.1038/s41598-022-11123-wMouseEndothelial;epithelial;mesothelial cell
Chinas 2022 Metabolites2022Chiñas Merlin A, Gonzalez K, Mockler S, Perez Y, Jia UA, Chicco AJ, Ullevig SL, Chung E (2022) Switching to a standard chow diet at weaning improves the effects of maternal and postnatal high-fat and high-sucrose diet on cardiometabolic health in adult male mouse offspring. https://doi.org/10.3390/metabo12060563MouseHeart
Serna 2022 BEC2022Serna JDC, Ramos VM, Cabral-Costa JV, Vilas-Boas EA, Amaral AG, Ohya G, da Silva CCC, Kowaltowski AJ (2022) Measuring mitochondrial Ca2+ efflux in isolated mitochondria and permeabilized cells. Bioenerg Commun 2022.7. https://doi.org/10.26124/bec:2022-0007Human
Mouse
Liver
Other cell lines
Guo 2022 Sci Adv2022Guo Q, Xu Z, Zhou D, Fu T, Wang W, Sun W, Xiao L, Liu L, Ding C, Yin Y, Zhou Z, Sun Z, Zhu Y, Zhou W, Jia Y, Xue J, Chen Y, Chen XW, Piao HL, Lu B, Gan Z (2022) Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4. https://doi.org/10.1126/sciadv.abo0340MouseSkeletal muscle
Fat
Deng 2022 Cell Mol Life Sci2022Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM (2022) Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. https://doi.org/10.1007/s00018-022-04453-5HumanEndothelial;epithelial;mesothelial cell
Baglivo 2022 BEC2022Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. Bioenerg Commun 2022.8. https://doi.org/10.26124/bec:2022-0008HEK
Crowder 2022 Islets2022Crowder JJ, Zeng Z, Novak AN, Alves NJ, Linnemann AK (2022) Stabilization protects islet integrity during respirometry in the Oroboros Oxygraph-2K analyzer. Islets 14:128-38.MouseIslet cell;pancreas;thymus
Rees 2022 J Exp Biol2022Rees BB, Reemeyer JE, Irving BA (2022) Interindividual variation in maximum aerobic metabolism varies with gill morphology and myocardial bioenergetics in Gulf killifish. https://doi.org/10.1242/jeb.243680Fishes
Rios-Morales 2022 Biochim Biophys Acta Mol Basis Dis2022Rios-Morales M, Vieira-Lara MA, Homan E, Langelaar-Makkinje M, Gerding A, Li Z, Huijkman N, Rensen PCN, Wolters JC, Reijngoud DJ, Bakker BM (2022) Butyrate oxidation attenuates the butyrate-induced improvement of insulin sensitivity in myotubes. https://doi.org/10.1016/j.bbadis.2022.166476MouseSkeletal muscle
Belosludtseva 2022 Membranes (Basel)2022Belosludtseva NV, Pavlik LL, Belosludtsev KN, Saris NL, Shigaeva MI, Mironova GD (2022) The short-term opening of cyclosporin A-independent palmitate/Sr 2+-induced pore can underlie ion efflux in the oscillatory mode of functioning of rat liver mitochondria. Membranes (Basel) 12:667. https://doi.org/10.3390/membranes12070667RatLiver
Felix 2022 Chemosphere2022Félix L, Carreira P, Peixoto F (2022) Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio). https://doi.org/10.1016/j.chemosphere.2022.136895Zebrafish
Fishes
Nervous system
Liver
Zhang 2022 Ecotoxicol Environ Saf2022Zhang Y, Yuan F, Li P, Gu J, Han J, Ni Z, Liu F (2022) Resveratrol inhibits HeLa cell proliferation by regulating mitochondrial function. https://doi.org/10.1016/j.ecoenv.2022.113788HumanHeLa
Sarabhai 2022 Diabetologia2022Sarabhai T, Mastrototaro L, Kahl S, Bönhof GJ, Jonuscheit M, Bobrov P, Katsuyama H, Guthoff R, Wolkersdorfer M, Herder C, Meuth SG, Dreyer S, Roden M (2022) Hyperbaric oxygen rapidly improves tissue-specific insulin sensitivity and mitochondrial capacity in humans with type 2 diabetes: a randomised placebo-controlled crossover trial. Diabetologia 66:57-69. https://doi.org/10.1007/s00125-022-05797-0HumanSkeletal muscle
Fat
Tang 2022 Sci China Life Sci2022Tang G, Ma C, Li L, Zhang S, Li F, Wu J, Yin Y, Zhu Q, Liang Y, Wang R, Huang H, Zhao TJ, Yang H, Li P, Chen FJ (2022) PITPNC1 promotes the thermogenesis of brown adipose tissue under acute cold exposure. https://doi.org/10.1007/s11427-022-2157-yMouseFat
Takada 2022 Proc Natl Acad Sci U S A2022Takada S, Maekawa S, Furihata T, Kakutani N, Setoyama D, Ueda K, Nambu H, Hagiwara H, Handa H, Fumoto Y, Hata S, Masunaga T, Fukushima A, Yokota T, Kang D, Kinugawa S, Sabe H (2022) Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure. Proc Natl Acad Sci U S A 119: e2203628119.MouseHeart
Formiga-Jr 2022 J Vis Exp2022Formiga-Jr MA, Camacho-Pereira J (2022) Assessing mitochondrial function in sciatic nerve by high-resolution respirometry. J Vis Exp 183:e63690. https://doi.org/10.3791/63690MouseNervous system
Cherix 2022 Mol Psychiatry2022Cherix A, Poitry-Yamate C, Lanz B, Zanoletti O, Grosse J, Sandi C, Gruetter R, Cardinaux JR (2022) Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior. https://doi.org/10.1038/s41380-022-01791-5MouseNervous system
Xu 2022 Sci Adv2022Xu H, Ahn B, Van Remmen H (2022) Impact of aging and oxidative stress on specific components of excitation contraction coupling in regulating force generation. Sci Adv 8:eadd7377. https://doi.org/10.1126/sciadv.add7377MouseSkeletal muscle
Op den Kamp 2022 Mol Metab2022Op den Kamp YJM, Gemmink A, de Ligt M, Dautzenberg B, Kornips E, Jorgensen JA, Schaart G, Esterline R, Pava DA, Hoeks J, Schrauwen-Hinderling VB, Kersten S, Havekes B, Koves TR, Muoio DM, Hesselink MKC, Oscarsson J, Phielix E, Schrauwen P (2022) Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism. https://doi.org/10.1016/j.molmet.2022.101620
Zhang 2022 Int J Mol Sci2022Zhang A, Gupte AA, Chatterjee S, Li S, Ayala AG, Miles BJ, Hamilton DJ (2022) Enhanced succinate oxidation with mitochondrial complex II reactive oxygen species generation in human prostate cancer. https://doi.org/10.3390/ijms232012168HumanGenital
Meszaros 2022 EBioMedicine2022Meszaros AT, Hofmann J, Buch ML, Cardini B, Dunzendorfer-Matt T, Nardin F, Blumer MJ, Fodor M, Hermann M, Zelger B, Otarashvili G, Schartner M, Weissenbacher A, Oberhuber R, Resch T, Troppmair J, Öfner D, Zoller H, Tilg H, Gnaiger E, Hautz T, Schneeberger S (2022) Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome. EBioMedicine 85:104311. https://doi.org/10.1016/j.ebiom.2022.104311HumanLiver
Brown 2022 Redox Biol2022Brown JL, Peelor FF 3rd, Georgescu C, Wren JD, Kinter M, Tyrrell VJ, O'Donnell VB, Miller BF, Van Remmen H (2022) Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy. Redox Biol 57:102518. https://doi.org/10.1016/j.redox.2022.102518MouseSkeletal muscle
Cano-Sanchez 2022 PLoS Negl Trop Dis2022Cano-Sanchez M, Ben-Hassen K, Louis OP, Dantin F, Gueye P, Roques F, Mehdaoui H, Resiere D, Neviere R (2022) Bothrops lanceolatus snake venom impairs mitochondrial respiration and induces DNA release in human heart preparation. https://doi.org/10.1371/journal.pntd.0010523HumanHeart
Vizuete 2022 J Neuroinflammation2022Vizuete AFK, Fróes F, Seady M, Zanotto C, Bobermin LD, Roginski AC, Wajner M, Quincozes-Santos A, Gonçalves CA (2022) Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway. https://doi.org/10.1186/s12974-022-02612-wRatNervous system
Babylon 2022 Int J Mol Sci2022Babylon L, Schmitt F, Franke Y, Hubert T, Eckert GP (2022) Effects of combining biofactors on bioenergetic parameters, Aβ levels and survival in Alzheimer model organisms. https://doi.org/10.3390/ijms23158670HumanNeuroblastoma
Dieter 2022 Int J Mol Sci2022Dieter F, Esselun C, Eckert GP (2022) Redox active α-lipoic acid differentially improves mitochondrial dysfunction in a cellular model of Alzheimer and its control cells. https://doi.org/10.3390/ijms23169186HumanNeuroblastoma
Donnarumma 2022 Nat Commun2022Donnarumma E, Kohlhaas M, Vimont E, Kornobis E, Chaze T, Gianetto QG, Matondo M, Moya-Nilges M, Maack C, Wai T (2022) Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure. https://doi.org/10.1038/s41467-022-34316-3MouseHeart
Karavyraki 2022 BEC2022Karavyraki M, Gnaiger E, Porter RK (2022) Bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells. Bioenerg Commun 2022.11. https://doi.org/10.26124/bec:2022-0011Human
Donnelly 2022 BEC2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12.v2. https://doi.org/10.26124/bec:2022-0012.v2
Tilokani 2022 Sci Adv2022Tilokani L, Russell FM, Hamilton S, Virga DM, Segawa M, Paupe V, Gruszczyk AV, Protasoni M, Tabara LC, Johnson M, Anand H, Murphy MP, Hardie DG, Polleux F, Prudent J (2022) AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology. https://doi.org/10.1126/sciadv.abo7956HumanOther cell lines
Cho 2022 BMC Med2022Cho J, Johnson BD, Watt KD, Niven AS, Yeo D, Kim CH (2022) Exercise training attenuates pulmonary inflammation and mitochondrial dysfunction in a mouse model of high-fat high-carbohydrate-induced NAFLD. https://doi.org/10.1186/s12916-022-02629-1MouseLung;gill
Delfinis 2022 JCI Insight2022Delfinis LJ, Bellissimo CA, Gandhi S, DiBenedetto SN, Garibotti MC, Thuhan AK, Tsitkanou S, Rosa-Caldwell ME, Rahman FA, Cheng AJ, Wiggs MP, Schlattner U, Quadrilatero J, Greene NP, Perry CG (2022) Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress. https://doi.org/10.1172/jci.insight.155147MouseSkeletal muscle
Gutierrez 2022 Cell Rep Med2022Gutierrez AD, Gao Z, Hamidi V, Zhu L, Saint Andre KB, Riggs K, Ruscheinsky M, Wang H, Yu Y, Miller C 3rd, Vasquez H, Taegtmeyer H, Kolonin MG (2022) Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocytes. https://doi.org/10.1016/j.xcrm.2022.100813MouseFat
Ceja-Galicia 2022 Antioxidants (Basel)2022Ceja-Galicia ZA, García-Arroyo FE, Aparicio-Trejo OE, El-Hafidi M, Gonzaga-Sánchez G, León-Contreras JC, Hernández-Pando R, Guevara-Cruz M, Tovar AR, Rojas-Morales P, Aranda-Rivera AK, Sánchez-Lozada LG, Tapia E, Pedraza-Chaverri J (2022) Therapeutic effect of curcumin on 5/6Nx hypertriglyceridemia: association with the improvement of renal mitochondrial β-oxidation and lipid metabolism in kidney and liver. Antioxidants (Basel) 11:2195. https://doi.org/10.3390/antiox11112195RatKidney
Gonzalez-Franquesa 2022 Redox Biol2022Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, Fernández-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, Miró-Blanch J, Oemer G, Duran X, Sanchez-Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Castaño C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, Fernández-Veledo S, Enríquez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales-Pardo M, Guimerà R, Blüher M, Martín-Subero JI, Garcia-Roves PM (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. https://doi.org/10.1016/j.redox.2022.102353MouseSkeletal muscle
Nervous system
Liver
Fat
Torres-Quesada 2022 Cancers (Basel)2022Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. Cancers (Basel) 14:3917. https://doi.org/10.3390/cancers14163917HumanOther cell lines
Fets 2022 Commun Biol2022Fets L, Bevan N, Nunes PM, Campos S, Dos Santos MS, Sherriff E, MacRae JI, House D, Anastasiou D (2022) MOG analogues to explore the MCT2 pharmacophore, α-ketoglutarate biology and cellular effects of N-oxalylglycine. https://doi.org/10.1038/s42003-022-03805-yRatIslet cell;pancreas;thymus
Smith 2022 J Pineal Res2022Smith KLM, Swiderska A, Lock MC, Graham L, Iswari W, Choudhary T, Thomas D, Kowash HM, Desforges M, Cottrell EC, Trafford AW, Giussani DA, Galli GLJ (2022) Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex-dependent manner. J Pineal Res 73:e12821. https://doi.org/10.1111/jpi.12821RatHeart
VanLieshout 2022 Mol Metab2022vanLieshout TL, Stouth DW, Hartel NG, Vasam G, Ng SY, Webb EK, Rebalka IA, Mikhail AI, Graham NA, Menzies KJ, Hawke TJ, Ljubicic V (2022) The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology. Mol Metab 64:101555. https://doi.org/10.1016/j.molmet.2022.101555MouseSkeletal muscle
Long 2022 Cell Commun Signal2022Long C, Guo R, Han R, Li K, Wan Y, Xu J, Gong X, Zhao Y, Yao X, Liu J (2022) Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells. https://doi.org/10.1186/s12964-022-00916-1HumanMacrophage-derived
Laehteenmaeki 2022 Physiol Rep2022Lähteenmäki EI, Koski M, Koskela I, Lehtonen E, Kankaanpää A, Kainulainen H, Walker S, Lehti M (2022) Resistance exercise with different workloads have distinct effects on cellular respiration of peripheral blood mononuclear cells. https://doi.org/10.14814/phy2.15394HumanBlood cells
Trewin 2022 BMC Biol2022Trewin AJ, Silver J, Dillon HT, Della Gatta PA, Parker L, Hiam DS, Lee YP, Richardson M, Wadley GD, Lamon S (2022) Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle. https://doi.org/10.1186/s12915-022-01366-4MouseSkeletal muscle
Wu 2022 Antioxidants (Basel)2022Wu YL, Chang JC, Chao YC, Chan H, Hsieh M, Liu CS (2022) In vitro efficacy and molecular mechanism of curcumin analog in pathological regulation of spinocerebellar ataxia type 3. https://doi.org/10.3390/antiox11071389HumanNeuroblastoma
Fialova 2022 Biomed Pharmacother2022Fialova JL, Hönigova K, Raudenska M, Miksatkova L, Zobalova R, Navratil J, Šmigová J, Moturu TR, Vicar T, Balvan J, Vesela K, Abramenko N, Kejik Z, Kaplanek R, Gumulec J, Rosel D, Martasek P, Brábek J, Jakubek M, Neuzil J, Masarik M (2022) Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration. https://doi.org/10.1016/j.biopha.2022.113582HumanEndothelial;epithelial;mesothelial cell
Belal 2022 Biomedicines2022Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V (2022) Glutamate-induced deregulation of krebs cycle in mitochondrial encephalopathy lactic acidosis syndrome stroke-like episodes (MELAS) syndrome is alleviated by ketone body exposure. https://doi.org/10.3390/biomedicines10071665HumanNeuroblastoma
O'Hanlon 2022 Neurobiol Dis2022O'Hanlon ME, Tweedy C, Scialo F, Bass R, Sanz A, Smulders-Srinivasan TK (2022) Mitochondrial electron transport chain defects modify Parkinson's disease phenotypes in a Drosophila model. https://doi.org/10.1016/j.nbd.2022.105803Drosophila
Zhang 2022 Nat Metab2022Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC (2022) The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK. https://doi.org/10.1038/s42255-022-00640-7MouseSkeletal muscle
McKenna 2022 J Appl Physiol (1985)2022McKenna CF, Salvador AF, Keeble AR, Khan NA, De Lisio M, Konopka AR, Paluska SA, Burd NA (2022) Muscle strength after resistance training correlates to mediators of muscle mass and mitochondrial respiration in middle-aged adults. J Appl Physiol (1985) 133:572-84. https://doi.org/10.1152/japplphysiol.00186.2022HumanSkeletal muscle
Nadeu 2022 Nat Med2022Nadeu F, Royo R, Massoni-Badosa R, Playa-Albinyana H, Garcia-Torre B, Duran-Ferrer M, Dawson KJ, Kulis M, Diaz-Navarro A, Villamor N, Melero JL, Chapaprieta V, Dueso-Barroso A, Delgado J, Moia R, Ruiz-Gil S, Marchese D, Giró A, Verdaguer-Dot N, Romo M, Clot G, Rozman M, Frigola G, Rivas-Delgado A, Baumann T, Alcoceba M, González M, Climent F, Abrisqueta P, Castellví J, Bosch F, Aymerich M, Enjuanes A, Ruiz-Gaspà S, López-Guillermo A, Jares P, Beà S, Capella-Gutierrez S, Gelpí JL, López-Bigas N, Torrents D, Campbell PJ, Gut I, Rossi D, Gaidano G, Puente XS, Garcia-Roves PM, Colomer D, Heyn H, Maura F, Martín-Subero JI, Campo E (2022) Detection of early seeding of Richter transformation in chronic lymphocytic leukemia. https://doi.org/10.1038/s41591-022-01927-8HumanLymphocyte
Blood cells
Mandic 2022 J Comp Physiol B2022Mandic M, Frazier AJ, Naslund AW, Todgham AE (2022) A comparative and ontogenetic examination of mitochondrial function in antarctic notothenioid species. https://doi.org/10.1007/s00360-022-01461-6FishesHeart
... further results
O2k-Publications in the MiPMap

O2k-Publications: Oxygraph-2k- Abstracts

Sort in ascending/descending order by a click on one of the small symbols in squares below.
 YearReferenceOrganismTissue;cell
Umbrasas 2024 Abstract IOC1672024Umbrasas D, Pampuščenko K, Gružaitė J, Morkūnienė R, Smirnovas V, Borutaitė V (2024) Extracellular alpha-synuclein and S100A9 species cause a shift in microglial energy metabolism. Mitochondr Physiol Network 28.12.MouseNervous system
Buck 2024 Abstract IOC1672024Buck AC, Dube A, Maarman G, Bardien S (2024) Curcumin-encapsulated nanoparticles to target mitochondrial dysfunction in a cellular model of Parkinson’s disease. Mitochondr Physiol Network 28.12.
Sobotka 2024 EBEC2024
Ondrej Sobotka
Sobotka O, Cardoso L, Garcia-Souza L, Sobotka L, Gnaiger E (2024) The effect of glucose on mitochondrial respiration in hepatocellular carcinoma cells. EBEC 2024.
Human
Herpe 2024 Abstract IOC1632024Herpe L, Pichaud N (2024) Investigating the importance of mtG3PDH in mitochondrial flexibility during environmental and physiological changes. Mitochondr Physiol Network 28.11.
Nizami 2024 Abstract IOC1632024Nizami HL, Szybowska P, Singhal P, Lee CF (2024) Investigating the effect of Nampt overexpression on cardiac mitochondrial respiration in Ndufs4-cKO mice. Mitochondr Physiol Network 28.11.MouseHeart
Mokoena 2024 Abstract IOC1632024Mokoena KR, Webster I, Genis A, Boltman T, Cambell J, Holm J, Mbombela V, Adoga JO, Everson FP, Maarman GJ, Strijdom H (2024) Investigating mitochondrial function in HIV-associated cardiometabolic disease: preliminary findings from a South African population. Mitochondr Physiol Network 28.11.
Dantas 2024 Abstract IOC1632024Dantas WS, Heintz EC, Zunica ERM, Dousay M, Davuluri G, Yu CS, Murphy MP, Axelrod CL, Kirwan JP (2024) Mito-Q supplementation reverses sarcopenic obesity in aged mice by restoring mitochondrial function and enhancing antioxidant response. Mitochondr Physiol Network 28.11.Mouse
Donnelly 2024 EU-METAHEART MC2 Meeting2024Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Kayser B, Place N, Gnaiger E (2024) Functional hypoxia in cardiac mitochondria: effects on oxidative phosphorylation, mitochondrial membrane potential, redox state of coenzyme Q, and calcium uptake. EU-METAHEART MC2 Meeting 2024 Antalya TR.MouseHeart
Baglivo 2023 ESCI Prague2023
Baglivo Eleonora
Baglivo E, Timon-Gomez A, Gnaiger E (2023) The cytochrome c test for respirometric quality control of the integrity of the mitochondrial outer membrane. 57th Annual Scientific Meeting of the European Society for Clinical Investigation.
Human
Bovines
Heart
Liver
HEK
Saleem 2023 MiPschool Obergurgl2023
MiPsociety
Mitochondrial physiology in cardiac muscle of deer mice native to high altitude.
MouseHeart
Strich 2023 MiPschool Obergurgl2023
MiPsociety
Bioenergetic profiling of kinase inhibitors reveals drug off-targer effects in colon cancer cell models
Stankova 2023 MiP20232023
Stankova Pavla
Effect of telmisartan on nutritionally induced nonalcoholic steatohepatitis in mice.
MouseLiver
Valencia 2023 MiP20232023
MiPsociety
T-cell mitochondria exhibit a functional decline with obesity that is aggravated by weight loss.
HumanBlood cells
Guerrier 2023 MiP20232023
Guerrier Lisa
Human white adipose tissue mitochondrial respiration: effect of body composition
HumanFat
Owesny 2023 MiP20232023
Owesny Patricia
Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.
MouseHeart
Pesta 2023 MiP20232023
Dominik Pesta
Respiratory capacity of skeletal muscle and peripheral blood mononuclear cells of male and female individuals with type 2 diabetes.
Skeletal muscle
Blood cells
Timon-Gomez 2023 EUROMIT2023 Bologna2023
Timon-Gomez Alba
Timon-Gomez A, Cardoso L, Baglivo E, Doerrier C, Gnaiger E (2023) Mitochondrial injury in warm ischemia studied by high-resolution respirometry. EUROMIT2023 International Conference on Mitochondrial Pathology.
Human
Mouse
Heart
Nervous system
HEK
Schmitt 2023 BPS2023 San Diego2023
Erich Gnaiger
Schmitt S, Cardoso LHD, Cecatto C, Komlodi T, Gnaiger Erich (2023) Mitochondrial bioenergetics – a quantitative analytical and diagnostic approach. 67th Annual Meeting of the Biophysical Society.
Cecatto 2023 BPS2023 San Diego2023
Sabine Schmitt
Cecatto C, Schmitt Sabine, Cardoso L, Videja M, Dambrova M, Makrecka-Kuka M, Liepinsh E, Gnaiger E (2023) Contribution of fatty acid oxidation to respiratory control in brain mitochondria. 67th Annual Meeting of the Biophysical Society.
MouseHeart
Nervous system
Kidney
Cardoso 2023 BPS2023 San Diego2023
Erich Gnaiger
Cardoso LHD, Timon-Gomez A, Doerrier C, Garcia-Souza LF, Gnaiger Erich (2023) Respirometric substrate-uncoupler-inhibitor titration protocols for carbohydrate and fatty acid metabolism: from heart to brain mitochondria. 67th Annual Meeting of the Biophysical Society.
Heart
Nervous system
Baelde 2023 Abstract IOC1602023Baelde R, Fortes Monteiro A, Nollet E, Galli R, Strom J, van der Velden J, Ottenheijm C, de Winter J (2023) Kbtbd13R408C-knockin mouse model elucidates mitochondrial pathomechanism in NEM6. Mitochondr Physiol Network 28.01.Mouse
Eldeeb 2023 Abstract IOC1622023Eldeeb M, Fontanesi F (2023) Differential substrate utilization by mitochondrial respiratory supercomplexes. Mitochondr Physiol Network 28.02
Pino 2023 Abstract IOC1622023Pino MF, Kapar SG, Laurent NL, Erickson ML, Sparks LM (2023) Characterization of human subcutaneous adipose-derived stem cells isolated from healthy young and old individual. Mitochondr Physiol Network 28.02
Van Doan 2023 Abstract IOC1622023Van Doan K, Luongo TS, Mukherjee S, Baur JA (2023) Mouse cardiac mitochondria are resilient to Nampt-dependent NAD+ los. Mitochondr Physiol Network 28.02
Magierecka 2023 Abstract IOC1602023Magierecka A, McLennan D, Dawson N, Millet C, Metcalfe NB (2023) Sustained swimming performance is independent of organism-level and mitochondrial-level metabolism in European minnows. Mitochondr Physiol Network 28.01.Fishes
Komlodi 2023 EUROMIT2023 Bologna2023Komlódi T, Silva FSG, Duarte AI, Mena D, Garcia-Souza LF, Makrecka-Kuka M, Bento G, Grilo LF, Oliveira PJ, Gnaiger E (2023) Off-target effects of etomoxir: inhibition of mitochondrial Complex I and fatty acid oxidation. EUROMIT2023 International Conference on Mitochondrial Pathology.Human
Mouse
Nervous system
Liver
McLennan 2023 Abstract IOC1602023McLennan D (2023) Maximal rates of mitochondrial oxidative phosphorylation predict territorial performance in brown trout. Mitochondr Physiol Network 28.01.Fishes
Abella 2023 Abstract IOC1602023Abella P, Valez V, Vaamonde L, Blasina F, Rodriguez-Rey M (2023) Severe acute neonatal hypoxia: mitochondrial dysfunction at an animal model and the role of nitric oxide. Mitochondr Physiol Network 28.01.PigNervous system
Warnaar 2023 Abstract IOC1602023Warnaar V, Nassar A, Nollet E, Michels M, Kuster D, Ochala J, Buikema JW, van der Velden J (2023) Effect of Mavacamten on the myofilament-mitochondrial axis in hypertrophic cardiomyopathy with and without sarcomere mutation. Mitochondr Physiol Network 28.01.
Leo 2023 ESCI Prague2023
Leo Elettra
Leo E, Zdrazilova L, Garcia-Souza LF, Åsander-Frostner E, Elmér E, Gnaiger E (2023) High-resolution respirometry is comparable in 0.5 mL and 2.0 mL chamber volumes: studies with platelets, permeabilized fibroblasts, and isolated mitochondria. 57th Annual Scientific Meeting of the European Society for Clinical Investigation.
Timon-Gomez 2023 GIBB2023
Timon-Gomez Alba
Timón-Gómez A, Cardoso LHD, Doerrier C, Garcia-Souza LF, Gnaiger E (2023) A reference substrate-uncoupler-inhibitor titration protocol to create a mitochondrial pathway and coupling control database. Third international GIBB meeting.
Donnelly 2022 Abstract Bioblast20222.1. «10+5»
Donnelly Chris
Donnelly Chris, Schmitt S, Cecatto C, Cardoso L, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint« »Watch the presentation«
Cardoso 2022 Abstract Bioblast20224.3. «10+5»
Luiza Cardoso
Cardoso Luiza HD, Doerrier C, Donnelly C, Komlódi T, Gnaiger E (2022) Redox monitoring and respiration - a new horizon with the NextGen-O2k. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
MouseLiver
HEK
Lerink 2022 Abstract Bioblast20226.5. «5 min»
Lerink Lente JS
Lerink Lente JS, Lindeman JHN (2022) Renal respiratory conductance: a complex matter. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
Kidney
Bergmeister 2022 Abstract Bioblast2022P11.
Bergmeister Lisa
Bergmeister Lisa, Doerrier C, Gnaiger E, Schwarzer C (2022) The role of enkephalin in hypoxic preconditioning. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Mouse
Axelrod 2022 Abstract Bioblast20223.6. «5 min»
Christopher Axelrod
Axelrod Christopher L, Heintz EC, Albaugh VL, Kirwan JP (2022) Segmental regulation of intestinal mitochondrial function. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
MouseEndothelial;epithelial;mesothelial cell
Cecatto 2022 Abstract Bioblast20225.1. «10+5»
Cecatto Cristiane
Cecatto Cristiane, Cardoso LHD, Gnaiger E (2022) Mitochondrial calcium uptake capacity is lower than calcium retention capacity in the presence and absence of cyclosporin A. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
MouseLiver
Kolonics 2022 Abstract Bioblast2022P16.
Kolonics Attila
Kolonics Attila, Léner V, Kutasi B, Kutasi J (2022) Effects of Scenedesmus rubescens extract on Paraquat induced parkinsonism model in SH-SY5Y cells and mitochondrial dysfunction. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
MouseNervous system
Goulding 2022 Abstract Bioblast20227.2. «5 min»
Goulding Richie P
Goulding Richie P, Strating S, van der Laan M, Noort W, Kolodyazhna A, Bloemers FW, Wüst RCI (2022) Mitochondrial function is not impaired in type 1 diabetes but does not respond to 4-weeks endurance training. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
HumanSkeletal muscle
Isola 2022 Abstract Bioblast2022P12.
Isola Raffaella
Isola Raffaella, Noli R, Isola M, Crisafulli A, Vargiu R, Loy F, Lai Y (2022) In rat brain and heart acute hypoxia induced mild changes in OXPHOS in both sexes. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
RatHeart
Nervous system
Chabi 2022 Abstract Bioblast20227.3. «5 min»
Chabi Beatrice
Colomb M, Tuifua L, Bertrand-Gaday C, Pessemesse L, Vernus B, Asikan E, Py G, Ollendorff V, Chabi Beatrice (2022) Coordination between mitochondrial-associated membranes MAMs, mitochondrial function and protein synthesis in exercised and myopathic muscles. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
MouseSkeletal muscle
Eggelbusch 2022 Abstract Bioblast20227.1. «5 min»
Eggelbusch Moritz
Eggelbusch Moritz, Hendrickse P, Schoonen R, Giakoumaki I, Kerkhoff TJ, Grootemaat AE, Rittweger J, Ganse B, Weeghel van M, Mulder ER, Degens H, Wüst RCI (2022) Nutrient overload and insulin resistance precede reductions in mitochondrial respiration in skeletal muscle after bed rest. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
HumanSkeletal muscle
Granata 2022 Abstract Bioblast20223.3. «5 min»
Granata Cesare
Granata Cesare (2022) Exercise training-induced enhancement of electron flow in the OXPHOS system is more important than increasing the OXPHOS machinery content to improve ATP generation in human skeletal muscle. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
HumanSkeletal muscle
Magri 2022 Abstract Bioblast20228.5. «5 min»
Magrì Andrea
Magrì Andrea, Cubisino SAM, De Pinto V, Messina A (2022) Modulation of mitochondrial respiration in ALS cells by hexokinase-based peptides: a novel therapeutic approach to fight neurodegeneration. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
HumanNervous system
Gnaiger 2022 ESCI Bari2022
Erich Gnaiger
Gnaiger E (2022) Bioenergetic cluster analysis – diagnostic evaluation of mitochondrial respiratory control in human fibroblasts. 56th Annual Scientific Meeting of the European Society for Clinical Investigation.
HumanFibroblast
Bettinazzi 2022 Abstract Bioblast2022P01.
Bettinazzi Stefano
Bettinazzi Stefano, Camus F, Dowling DK, Lane N (2022) Linking the mitonuclear genotype with mitochondrial function and organismal fitness. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Komlodi 2022 Abstract Bioblast20223.1. «10+5»
Komlodi Timea
Komlódi Timea, Tretter L (2022) The protonmotive force – not merely membrane potential. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint« »Watch the presentation«
Cardoso 2022a EBEC2022
Luiza Cardoso
Cardoso LHD, Donnelly C, Komlódi T, Gnaiger E (2022) Characterizing electron transfer through the mitochondrial Q-junction from fatty acid oxidation and TCA cycle on HEK 293T cells: correlation with respiration. EBEC 2022.
HumanHEK
Cardoso 2022b EBEC2022
Luiza Cardoso
Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Instrumental quality control and evaluation of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells. EBEC 2022.
HumanHEK
Oliveira 2022 Abstract Bioblast-Aedes20223.7. «10+5»
Oliveira Marcus F
Gaviraghi A, Barletta ABF, Alves e Silva TL, Oliveira MP, Sorgine MHF, Oliveira Marcus F (2022) Sterile activation of innate immunity specifically target Complex I activity and flight dispersal in the major arbovirus vector Aedes aegypti. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
Hexapods
Schmitt 2022 EBEC2022
Sabine Schmitt
Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022.
HumanHEK
Cecatto 2022 EBEC2022
Cristiane Cecatto
Cecatto C, Cardoso LHD, Gnaiger E (2022) Mitochondrial calcium uptake capacity is lower than calcium retention capacity in the presence and absence of cyclosporin A. EBEC 2022.
MouseLiver
Ebanks 2022 Abstract Bioblast2022P09.
Brad Ebanks
Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of D. melanogaster. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Drosophila
Porter 2022 Abstract Bioblast20226.3. «10+5»
Porter Richard K
Karavyraki M, Gnaiger E, Porter Richard K (2022) A comparison of bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint« »Watch the presentation«
Human
Baglivo 2022a ESCI Bari2022
Baglivo Eleonora
Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Quality control of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells. 56th Annual Scientific Meeting of the European Society for Clinical Investigation.
HumanHEK
Cardoso 2022 ESCI Bari2022
Luiza Cardoso
Cardoso LHD, Donnelly C, Komlódi T, Gnaiger E (2022) Bioenergetic fingerprinting with coupling and pathway control of coenzyme Q redox state and respiration in permeabilized HEK 293T cells. 56th Annual Scientific Meeting of the European Society for Clinical Investigation.
HumanHEK
Gnaiger 2022 EBEC2022
Erich Gnaiger
Gnaiger E (2022) Bioenergetic cluster analysis – mitochondrial respiratory control in human fibroblasts. EBEC 2022.
HumanFibroblast
Gnaiger 2022 Abstract Bioblast-PB2022P03.
Erich Gnaiger
Went N, Di Marcello M, Gnaiger Erich (2022) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by high-resolution PhotoRespirometry. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint«
Algae
Schmitt 2022 Abstract Bioblast20222.2. «10+5»
Sabine Schmitt
Schmitt Sabine, Gnaiger E (2022) Using oxygen and hydrogen gas in studies of mitochondrial respiration and hydrogen peroxide production under hyperoxic, normoxic, and hypoxic conditions. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
HEK
Molina 2022 Abstract Bioblast20223.2. «10+5»
Molina Anthony JA
Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina Anthony JA (2022) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older women. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»Bioenergetics Communications« »Watch the presentation«
HumanBlood cells
Baglivo 2022b ESCI Bari2022
Baglivo Eleonora
Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility in high-resolution respirometry. 56th Annual Scientific Meeting of the European Society for Clinical Investigation.
Fromme 2021 Abstract Kalorimetrietage2021Fromme T (2021) Application of different respirometric assay systems to characterize the membrane permeabilization potency of saponins. Kalorimetrietage 2021.
Gnaiger 2020 APS Chicago2020Gnaiger E (2020) Aerobic exercise capacity and mitochondrial fitness: from muscle to brain. APS2020 Chicago.
Doerrier 2020 PaduaMuscleDays Poster2020Doerrier C, Gama-Perez P, Chabi B, Ost M, Distefano G, Pesta D, Dahdah N, Lemieux H, Holody C, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Calabria E, Casado M, Fernandez-Ortiz M, Acuna-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wuest R, Dayanidhi S, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen PM, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Commitment to reproducibility in mitochondrial respiration studies with permeabilized muscle fibers. PaduaMuscleDays.Human
Mouse
Skeletal muscle
Doerrier 2020 PaduaMuscleDays2020Doerrier C, Di Marcello M, Gnaiger E (2020) Commitment to reproducibility in targeting mitochondrial respiratory control: basic and advanced applications of the O2k-FluoRespirometer. PaduaMuscleDays.Skeletal muscle
Blood cells
Giakoumaki 2019 MiPschool Coimbra2019
MiPsociety
Mitochondrial respiration in human skeletal muscle after 60 days of best rest.
HumanSkeletal muscle
Minuzzi 2019 MiPschool Coimbra2019
MiPsociety
A pilot study on mitochondrial function of mouse skin using high-resolution respirometry.
MouseEndothelial;epithelial;mesothelial cell
Dias 2019 MiPschool Coimbra2019
Candida Dias
Protective effect of nitrite in brain ischemia/reperfusion via modulation of mitochondrial respiration.
RatNervous system
Abdel-Rahman 2019 MiPschool Coimbra2019
MiPsociety
Diurnal changes in calcium dynamics, respiratory function, and ROS production in cardiac mitochondria.
MouseHeart
Van der Ende 2019 MiPschool Coimbra2019
Miranda van der Ende
Mitochondrial respiration in muscle tissue of colon cancer patients.
HumanSkeletal muscle
Gao 2019 MiPschool Coimbra2019
MiPsociety
Effects on mitochondrial respiration of N-acyl amino acids versus common fatty acids.
RatSkeletal muscle
Garcia-Roves 2019 MiPschool Coimbra2019
Pablo Garcia-Roves
Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
MouseSkeletal muscle
Hachmo 2019 MiPschool Coimbra2019
Yafit Hachmo
The effect of hyperbaric oxygen therapy on mitochondrial function.
HumanSkeletal muscle
Stevanovic 2019 MiPschool Coimbra2019
MiPsociety
Gestational physical exercise offers prolonged protection to liver mitochondrial function of female offspring against deleterious effects of maternal gestational diabetes.
RatLiver
Santos 2019 MiPschool Coimbra2019
MiPsociety
Uncoupling Protein 1 inhibition and mitochondrial respiration in epicardial adipose tissue from hear failure patients.
HumanHeart
Fat
Fuertes-Agudo 2019 MiPschool Coimbra2019Marina Fuertes Agudo Role of COX-2 in liver and heart mitochondrial function.MouseHeart
Skeletal muscle
Liver
Wuest 2019 MiPschool Coimbra2019
Rob Wüst
Altered mitochondrial metabolism in the diabetic heart.
Heart
Garcia 2019 MiPschool Coimbra2019
Geovana Garcia
Functional interactions between the Drosophila melanogaster mitochondrial glycerol-3-phosphate dehydrogenase and a xenotopically expressed alternative oxidase.
Drosophila
Evinova 2019 MiPschool Coimbra2019
MiPsociety
High resolution respirometry of neuroblastoma SK-N-SH and SH-SY 5Y cell lines.
HumanNeuroblastoma
Goncalves Debora 2019 MiPschool Coimbra2019
MiPsociety
Aging effects on mitochondrial control factors in Pink1 knockout Drosophila melanogaster.
Drosophila
Hatokova 2019 MiPschool Coimbra2019
MiPsociety
Influence the passage number on a respiration of SH-SY 5Y cells.
HumanNeuroblastoma
Goikoetxea-Usandizaga 2019 MiPschool Coimbra2019
Naroa Goikoetxea Usandizaga
Methylation Controlled J protein (MCJ): A therapeutic target in hepatic ischemia and reperfusion injury.
MouseLiver
Fulton 2019 Abstract IOC1392019Fulton MR, Davis MS (2019) Effect of hyperthermia on mitochondrial function in canine skeletal muscle. Mitochondr Physiol Network 24.01.DogSkeletal muscle
O’Brien 2019 Abstract IOC1392019O’Brien KM (2019) Mitochondrial form and function in Antarctic fishes. Mitochondr Physiol Network 24.01.FishesHeart
Joseph 2019 Abstract IOC1392019Joseph V, Arias-Reyes C, Soliz J (2019) Plasticity of brain mitochondrial respiration rates during acclimatization to chronic hypoxia in mice. Mitochondr Physiol Network 24.01.Mouse
Rat
Nervous system
Silva 2019 ESCI20192019Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir?Human
Mouse
Liver
Arandarcikaite 2019 ESCI20192019Arandarcikaite O, Borutaitė V (2019) Analysis of mitochondrial functions in ischemic brain model.RatNervous system
Speichinger 2019 Innov Surg Sci2019Speichinger F, Kamphues C, Gratl A, Frese J, Greiner A, Kreis M (2019) High Resolution Respirometry (HRR) of the smooth muscle in the intestine. Innov Surg Sci.HumanOther cell lines
Gnaiger 2019 NatureConference2019Gnaiger E, Passrugger M, Gallee L, Felipe F Garcia-Souza, Zdrazilova L, Doerrier C (2019) High-resolution respirometry and innovations in the Oroboros O2k-technology.HumanBlood cells
HEK
Fibroblast
Platelet
Rutai 2019 Crit Care2019Rutai A, Fejes R, Tallósy SZ, Poles M, Juhász L, Mészáros A, Boros M, Kaszaki J (2019) Potential role of endothelin receptors in the therapy of experimental sepsis. Crit Care.Rat
Abid 2019 J Clin Transl Sci2019Abid H, Hart C, Lanza I (2019) Effects of local interleukin-6 on mitochondrial physiology in skeletal muscle. J Clin Transl Sci.Skeletal muscle
Bastos Sant'Anna Silva 2019 Life Sciences Meeting 2019 Innsbruck AT2019Cellular succinate transport and mitochondrial respiratory function in prostate cancer.HumanGenital
De la Rosa Vargas 2019 Arch Cardiovasc Dis2019De la Rosa Vargas LE, Dale Abel E, Langer T, Wai T (2019) Metabolic regulation of heart failure caused by imbalanced mitochondrial dynamics. Arch Cardiovasc Dis.MouseHeart
Kandel 2019 Biophys J2019Kandel SM, Tomar N, Zheleznova N, Audi SH, Cowley Jr AW, Dash RK (2019) Calcium stimulation of mitochondrial respiration is substrate dependent and tissue specific. Biophys J.RatHeart
Kidney
Jang 2019 Crit Care Med2019Jang D, Hallisey S, Zhou V, Owiredu S, Shofer F, Greenwood J, Eckmann D (2019) Changes in inflammataion and mitochondrial function in blood cells obtained from patients with sepsis. Crit Care Med.Blood cells
Krako Jakovljevic 2019 MiP20192019
Nina Krako Jakovljevic
Lower insulin sensitivity differently affects mitochondrial coupling in liver and muscle cells.
Human
Mouse
Skeletal muscle
Liver
Silva 2019 MiPschool Coimbra2019
Filomena Pereira da Silva Grilo da Silva
Off-target effects of etomoxir on mitochondrial Complex I.
Human
Mouse
Liver
Sumbalova 2019b MiP20192019
Zuzana Sumbalova
The decline of mitochondrial respiration in isolated platelets after short-term storage.
HumanPlatelet
Sumbalova 2019a MiP20192019
Zuzana Sumbalova
Platelet mitochondrial function, coenzyme Q10, and oxidative stress in patients with chronic kidney diseases.
HumanPlatelet
Cardoso 2019 MiP20192019
Luiza Cardoso
Effects of glucose concentration in cell culture media on hepatocellular carcinoma HuH7 cells evaluated by high-resolution respirometry.
HumanLiver
Dahdah 2019 MiP20192019
Norma Dahdah
Approaches to assess mitochondrial respiration in white adipose tissue.
MouseFat
Tioli 2019 MiP20192019
MiPsociety
Involvement of mitochondrial respiratory supercomplexes in anti-bacterial innate immunity.
MouseHeart
Liver
Blood cells
Macrophage-derived
Lemieux 2019a MiP20192019
Hélène Lemieux
Partial prevention of oxidative stress damage to mitochondria with photobiomodulation.
Other invertebrates
Doerrier 2019 MiP20192019
Carolina Doerrier
Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers.
HumanSkeletal muscle
Chabi 2019 MiP20192019
Béatrice Chabi
Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
MouseSkeletal muscle
Blier 2019 MiP20192019
Pierre Blier
The secrets of extreme longevity from bivalves.
Molluscs
Holody 2019 MiP20192019
Claudia Holody
Sex-specific changes in neonatal cardiac mitochondrial function in response to perinatal iron deficiency.
RatHeart
Avram 2019 MiP20192019
Vlad Avram
Cell-permeable succinate bypasses statin-induced decrease in mitochondrial ATP-generating respiration in human platelets.
HumanPlatelet
Betiu 2019 MiP20192019
MiPsociety
Cell-permeable succinate improves amiodarone-induced mitochondrial Complex I and II inhibition in human platelets.
HumanPlatelet
Kruse 2019 MiP20192019
Caroline Kruse
Peripheral blood mononuclear cells to detect mitochondrial dysfunction in horses: a preliminary study.
HorseBlood cells
Scandalis 2019 Abstract IOC1412019Scandalis LM, Kramer P, Nelson B, Dozier S, Stone J, Kitzman D, Molina AJA (2019) Oxygen consumption of skeletal muscle in heart failure with preserved ejection fraction. Mitochondr Physiol Network 24.02.HumanSkeletal muscle
Tremblay 2019 Abstract IOC1412019Tremblay N, Leiva L, Haafke J, Meunier CL, Boersma M (2019) Effects of low-frequency noise and temperature on copepod performance. Mitochondr Physiol Network 24.02.Crustaceans
Gnaiger 2019 MiP20192019
Erich Gnaiger
OXPHOS capacity in human muscle tissue and body mass excess – the MitoEAGLE mission towards an integrative database (Version 6; 2020-01-12).
HumanSkeletal muscle
Lalic 2109 MiP20192019
Nebojsa Lalic
Pathophysiology of type 2 diabetes and mitochondrial dysfunction: possible therapeutic implications.
Skeletal muscle
Liver
Arnould 2019 MiP20192019
Thierry Arnould
Role of Sirtuin 3 in the differentiation of 3T3-L1 preadipocytes.
Fat
Timohhina 2019 MiP20192019
Natalja Timohhina
Metabolic effects of mitochondria-targeted antioxidant peptides in colorectal cancer cells.
HumanEndothelial;epithelial;mesothelial cell
Calabria 2019 MiPschool Coimbra2019
Elisa Calabria
Investigating mitochondrial function in blood cells by high-resolution respirometry: contribution to an interlaboratory study. MitoEAGLE WG4.
Blood cells
Pavlovic 2019 MiP20192019
Barbara Cannon
Effects of therapeutic metformin concentration on mitochondria in muscle cells.
MouseSkeletal muscle
Aid-Vanakova 2019 MiP20192019
MiPsociety
Adaptation of muscle OXPHOS in developing glucose intolerance - Wfs1 mice model.
MouseSkeletal muscle
Heart
Zujovic 2019 MiP20192019
Tijana Zujovic
Cell membrane permeabilization: digitonin optimization pitfalls.
Human
Mouse
Skeletal muscle
Liver
Lelcu 2019 MiP20192019
Theia Lelcu
Assessment of platelet respiration in blood malignancies: a pilot study in children and adults.
HumanPlatelet
Rodriguez 2019 Abstract IOC1412019Rodriguez E, Camus FM, Lane N (2019) Mitochondria as “flux capacitors”: the effect of mitonuclear incompatibilities on mitochondrial physiology, metabolomics profile and gene expression in D. melanogaster. Mitochondr Physiol Network 24.02.Drosophila
Axelrod 2019 Abstract IOC1412019Axelrod CL, Davuluri G, Zunica ERM, Noland RC, Hoppel CL, Kirwan JP (2019) Administration of BAM15 to obese C57BL/6J mice increases skeletal muscle fatty acid oxidation independent of OXPHOS or ETC capacity. Mitochondr Physiol Network 24.02.MouseSkeletal muscle
Revenco 2019 Abstract IOC1412019Revenco I, Lismont C, Baes M, Van Veldhoven PP, Fransen M (2019) Analysis of mitochondrial respiration in a cell line with regulatable peroxisomal hydrogen peroxide production. Mitochondr Physiol Network 24.02.HEK
Kramer 2019 Abstract IOC1412019Kramer P, Distefano G, Monte J, Mills A, Edmunds L, Jurczak M, Cummings SR, Kritchevsky S, Newman AB, Hepple RT, Goodpaster B, Coen PM, Molina A (2019) The Study of Muscle, Mobility, and Aging (SOMMA): A multi-institutional respirometry study. Mitochondr Physiol Network 24.02.HumanSkeletal muscle
Keppner 2018 MiP20182018
Gloria Keppner
Effects of cryopreservation of peripheral blood mononuclear cells.
Blood cells
Komlodi 2018b EBEC20182018Endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.MouseLiver
Keller 2018 MiP20182018
Markus A Keller
The structural molecular diversity of mitochondrial cardiolipins.
MouseHeart
Nervous system
Votion 2018 MiP20182018
Dominique-Marie Votion
Functional diagnosis of mitochondrial defects in equine atypical myopathy and targeted mitochondrial therapy: a preliminary study.
HorseSkeletal muscle
Lemieux 2018 MiP20182018
Helene Lemieux
Plasticity of a critical regulator of energy production under hypothermia, the phosphorylation system.
Other invertebrates
Evinova 2018 MiP20182018
MiPsociety
High-resolution respirometry of neuroblastoma SH-SY 5Y cell line.
HumanOther cell lines
Neuroblastoma
Escames 2018 MiP20182018
Germaine Escames
Suppression of AKT/mTOR pathway and activation of mitophagy by melatonin via mitocondrial regulation in head and neck cancer. Escames_Presentation
Human
Mouse
Other cell lines
Nemec 2018 MiP20182018
Michal Nemec
Aerobic/strength exercise intervention modulates skeletal muscle mitochondrial function in seniors.
HumanSkeletal muscle
Belosludtsev 2018 MiP20182018
MiPsociety
Effect of bedaquiline and delamanid on the functions of rat liver mitochondria.
RatLiver
Acuna-Castroviejo 2018 MiP20182018
Dario Acuna-Castroviejo
Mitochondria, melatonin, and neuroinflammation in Parkinson's disease. Acuna-Castroviejo_Presentation
MouseNervous system
Avram 2018 MiP20182018
MiPsociety
Cell-permeable succinate bypasses statin-induced mitochondrial complex I inhibition in human platelets. Avram_Presentation
HumanPlatelet
Pereira da Silva Grilo da Silva 2018 MiP20182018
Filomena Pereira da Silva Grilo da Silva
The unspecific effect of etomoxir on mitochondrial respiration.
Human
Mouse
Nervous system
Liver
Other cell lines
Danhelovska 2018 MiP20182018
MiPsociety
The relevance of ACBD3 protein in energy metabolism in various cell lines. Danhelovska_Presentation
HumanHEK
HeLa
Greyslak 2018 FASEB J2018Greyslak KT, Hetrick B, Takahashi DL, Dean T, Kievit P, Sullivan EL, McCurdy CE (2018) Exposure to a western-style diet during early development reduces skeletal muscle lipid metabolism and CI-dependent oxidative capacity in juvenile non-human primate offspring. FASEB J.Other mammalsSkeletal muscle
McCurdy 2018 Endocrine Reviews2018McCurdy CE, True C, Takahashi D, Hetrick B, Varlamov O, Roberts CT (2018) Chronic hyperandrogenemia impairs oxidative metabolism in skeletal muscle from adolescent female rhesus macaques. Endocrine Reviews.Other mammalsSkeletal muscle
Kidere 2018 MiP20182018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the effect of the mtDNA mutations on the OXPHOS system.
HumanOther cell lines
Platelet
Malagrino 2018 Free Radic Biol Med2018Malagrinò F, Zuhra K, Mastronicola D, Mascolo L, Vicente JB, Forte E, Giuffrè A (2018) H2S metabolism in colon cancer cells: Effect of hypoxia. Free Radic Biol Med.
Wilson 2018 Virginia Tech2018Wilson ZT, Perry JB, Brow DA (2018) High-resolution respirometry of heart mitochondria in healthy and stressed states. Virginia Tech.Heart
Liu 2018 Atherosclerosis Suppl2018Liu D (2018) Enhanced Trpc3-mediated mitochondrial respiratory dysfunction by inhibition of mitochondria-hexokinase in monocytes from hypertension rats. Atherosclerosis Suppl.RatBlood cells
Doerrier 2018 MiP2018c2018
Carolina Doerrier
Inter-laboratory study on human permeabilized myofibers: effects of fiber preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation.
HumanSkeletal muscle
Kuka 2018 MiP20182018
MiPsociety
The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.
RatHeart
Volska 2018 MiP20182018
Kristina Volska
The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Heart
Bastos Sant'Anna Silva 2018 TRANSMIT Bertinoro di Romagna IT2018Cellular succinate transport and mitochondrial respiratory function in prostate cancer.HumanHEK
Genital
Bastos Sant'Anna Silva 2018 Life Sciences Meeting 2018 Innsbruck AT2018Effect of cell-permeable succinate and malonate prodrugs on mitochondrial respiration in prostate cancer cells.Kidney
Other cell lines
HEK
Stevens 2018 Br J Anaesth2018Stevens JL, McKenna H, Murray A, Jell G, Guliyeva M, Martin D (2018) Effects of major hepato-pancreatico-biliary surgery and general anaesthesia on skeletal-muscle mitochondrial respiration: a pilot study. Br J Anaesth.HumanSkeletal muscle
Sobotka 2018 MiP20182018
Ondrej Sobotka
Measurement of ROS production under hypoxia and unexpected methodological pitfalls of Amplex UltraRed assay.
Mouse
Saccharomyces cerevisiae
Heart
Nervous system
Doerrier 2018 MiP2018a2018
Carolina Anneliese Doerrier
Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers.
MouseSkeletal muscle
Nollet 2018 IOC1302018Mitochondrial dysfunction in hypertrophic cardiomyopathy.MouseHeart
Blindheim 2018 IOC1342018Bioactive lipophilic substances and their effect on neuronal cells.Nervous system
McMaster 2018 Am J Obstet Gynecol2018Preeclampsia is associated with placental mitochondrial dysfunction.Human
Pranger 2018 Emerging Concepts in Mitochondrial Biology2018
PrangerF.JPG
High-resolution respirometry with a reduced chamber volume – which are the compromises in OXPHOS analysis?
Blood cells
Platelet
Chang 2018 Biophys J2018Mitochondrial dysfunction in malignant hyperthermia susceptible skeletal muscle.Human
Mouse
Skeletal muscle
Schoepf 2018 33rd Annual EAU Congress Copenhagen2018Shift of mitochondrial oxidative phosphorylation is associated with mtDNA mutational load in primary prostate cancer tissue.HumanGenital
Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT2018A respirometric cell viability test for peripheral-blood mononuclear cells and platelets.HumanBlood cells
Platelet
Chang 2018 Life Sciences Meeting 2018 Innsbruck AT2018pH dependence of mitochondrial respiration and H2O2 production in oral cancer cells – a pilot study.HumanHEK
Kidney
Doerrier 2018 ESCI20182018
Carolina Anneliese Doerrier
High-resolution respirometry, two techniques combined in one to explore mitochondrial function in health and disease
Human
Mouse
Heart
Skeletal muscle
Nervous system
Blood cells
HEK
Hunt 2018 J Urol2018Marked increase in mitochondrial respiration, hydrogen peroxide emitting potential and ATP production in the urothelium versus detrusor smooth muscle.MouseEndothelial;epithelial;mesothelial cell
Capek 2018 J Burn Res2018Evidence of functional brown adipose tissue in children with severe burns.HumanFat
Chao 2018 J Burn Care Res2018Altered renal and cardiac mitochondrial activity after 40% TBSA in a swine model.PigHeart
Kidney
Luis-Garcia 2018 Am J Respir Crit Care Med2018Contribution of the mitochondrial intrinsic pathway to the apoptosis resistance exhibited by fibroblasts from idiopathic pulmonary fibrosis.HumanLung;gill
Fibroblast
Pchelin 2018 IOC1302018Activation of heterodimeric receptor to erythropoietin with its agonist CdEPO regulates brain mitochondrial bioenergetics after local acute ischemia/reperfusion in C57BL/6 mice.MouseNervous system
Meszaros 2018 EBEC20182018Tissue- and substrate-specific patterns in the oxygen kinetics of mitochondrial respiration.MouseHeart
Nervous system
Liver
Andriessen 2018 IOC1302018Day-night rhythm in skeletal muscle metabolism of prediabetic men.HumanSkeletal muscle
Nickel 2018 IOC1302018Defects in mitochondrial calcium uptake precede defects of the respiratory chain in X-linked Barth syndrome cardiomyopathy.MouseHeart
Chang 2018 Br J Anaesth2018Oxygen metabolism in malignant hyperthermia susceptible skeletal muscle and the effects of static halothane exposure.Skeletal muscle
White 2018 J Anim Sci2018Differing mitochondrial capacity in two separate skeletal muscles from calm and temperamental Brahman heifers.BovinesSkeletal muscle
Wallace 2018 FASEB J2018Effects of H1/H2 histamine receptor blockade on mitochondrial function in rodent brain following prolonged exercise.RatNervous system
Koop 2018 11th Internat Confer Neonat Childh Pulmon Vasc Dis2018Decrease of polyunsaturated fatty acids in right ventricular dysfunction due to pressure overload.RatHeart
Komlodi 2018 EBEC20182018Electron supply to the Q-junction: assessment of mitochondrial respiration, H2O2 flux and the redox state of the Q-pool.MouseNervous system
Doerrier 2018 EBEC20182018
Carolina Anneliese Doerrier
Respiratory mapping of mitochondrial pathways for establishing a database of mitochondrial physiology.
Human
Mouse
Heart
Nervous system
Blood cells
HEK
Platelet
Han 2018 MiP20182018
MiPsociety
Mitochondrial functional changes elicited by a single near-infrared (670nm) exposure. Han_Presentation
HumanKidney
HEK
Stankova 2018 MiP20182018
Pavla Krivakova-Stankova
Impact of western diet on energy metabolism in mouse liver.
MouseLiver
Ounpuu 2018 MiP20182018
Lyudmila Ounpuu
Metabolic plasticity of cancer stem-like cells.
HumanStem cells
De Goede 2018 MiP20182018
MiPsociety
Timing of feeding behavior affects daily rhythms in body temperature and muscle mitochondrial metabolism.
RatSkeletal muscle
Puurand 2018 MiPschool Tromso E22018
MiPsociety
Intracellular energy-transfer networks in health and disease – the results of oxygraphic studies.
MouseHeart
Skeletal muscle
Wuest 2018 MiPschool Tromso D32018
Wuest Rob
Metabolic flexibility and mitochondrial function in the diabetic heart.
Pig
Mouse
Rat
Heart
Musiol 2018 MiPschool Tromso C42018
MiPsociety
Alpha-tomatine as a novel membrane-permeabilizing agent for mitochondrial respiration measurements.
HumanHEK
Bastos Sant'Anna Silva 2018 MiPschool Tromso C42018
Ana Bastos Sant'Anna
Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
HumanGenital
Zdrazilova 2018 MiPschool Tromso C42018
MiPsociety
Bioenergetic characterization of skin fibroblasts from patients with congenital disorders of glycosylation.
HumanFibroblast
Jansen 2018 MiPschool Tromso C22018
MiPsociety
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
MouseHeart
Skeletal muscle
Liver
Fat
Boardman 2018 MiPschool Tromso D32018
MiPsociety
High fat-load induces cardioprotection in hearts from obese mice.
MouseHeart
Iglesias-Gonzalez 2018 MiPschool Tromso E12018
Iglesias-GonzalezJ.JPG
Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos.
Amphibians
Makrecka-Kuka 2018 MiPschool Tromso E12018
Marina Makrecka-Kuka
Cardiac fatty acid oxidation: from in vitro to in vivo.
Heart
Cardoso 2018 MiPschool Tromso E22018
Luiza Helena Cardoso
Concomitant respiration and ATP production measurements to analyse P»/O2 ratios at physiological normoxia.
Garipi 2018 MiPschool Tromso E22018Phenotyping mitochondrial metabolism in Barrett’s metaplasia-dysplasia-adenocarcinoma sequence: respiratory capacity, extracelular proton flux and ROS productionHumanEndothelial;epithelial;mesothelial cell
Other cell lines
Siewiera 2018 MiPschool Tromso E22018
Karolina Siewiera
Effect of metformin treatment on blood platelet bioenergetics and platelet function in STZ-diabetic and non-diabetic rats.
RatPlatelet
Fischer 2018 MiPschool Tromso E22018
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
MouseHeart
Nervous system
Liver
Kidere 2018 MiPschool Tromso E22018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
HumanPlatelet
Chicco 2018 MiP2018c2018
Adam J Chicco
Role of mitochondria in skeletal muscle acclimatization to high-altitude.
HumanSkeletal muscle
Huete-Ortega 2018 MiPschool Tromso E22018High-resolution respirometry: new perspectives for the study of bioenergetics in algae and plants.Plants
Isola 2018 MiPschool Tromso C32018
Raffaela Isola
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
MouseHeart
Krajcova 2018 MiPschool Tromso E22018
Adela Krajcova
High-resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle.
HumanHeart
Goncalo Teixeira 2018 MiPschool Tromso C12018
MiPsociety
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
RatLiver
Heart
Kidney
Konopka 2018 FASEB J2018Konopka AR, Castor WM, Reid J, Schoenberg H, Laurin J, Wolff C, Hamilton K, Miller B (2018) Metformin blunts exercise-induced improvements in skeletal muscle mitochondrial respiration independent of changes in mitochondrial biogenesis. FASEB J.HumanSkeletal muscle
Rodriguez-Hernandez 2018 Free Radic Biol Med2018Rodriguez-Hernández A, Staňková P, González R, De la Rosa AJ, Álamo-Martinez JM, Marin-Gómez LM, Sobotka O, Kučera O, Padillo FJ, Červinková Z, Muntané J (2018) The alteration of mitochondrial function is associated with the induction of endoplasmic reticulum stress autophagy and apoptosis by Sorafenib in liver cancer cells. Free Radic Biol Med.Liver
Kappler 2018 J Lab Med2018Kappler L, Hoene M, Kollipara L, Li J, Hu C, van Törne C, Hauck S, Irmler M, Beckers J, de Angelis MH, Peter A, Xu G, Häring H, Weigert C, Sickmann A (2018) Systems medicine approach combining Multi-omics and functional analyses in hepatic and skeletal muscle mitochondria of pre-diabetic mice. J Lab Med.MouseSkeletal muscle
Liver
Kovalev 2018 EMBS2018Kovalev A, Sokolova I, Sukhotin A (2018) Allometry of mitochondrial respiration in mussels. EMBS.MolluscsLiver
Islet cell;pancreas;thymus
Li 2018 IBEC2018Li C, Li N, Zhang Y (2018) UPRmt and mitophagy are selectively activated depending on muscle fiber types in insulin resistant rats. IBEC.RatSkeletal muscle
Zhang 2018 IBEC2018Zhang X, Coen P (2018) Target mitochondria metabolism and energy expenditure in muscle atrophy, sarcopenia and cachexia. IBEC.MouseSkeletal muscle
Roy Chowdhury 2018 J Thorac Oncol2018Roy Chowdhury S, Saleh R, Girard C, Peltier C, Desautels D, Dawe D, Banerji V, Banerji S (2018) Targeting mitochondrial metabolism as a selective therapeutic approach in small cell lung cancer (SCLC). J Thorac Oncol.HumanLung;gill
Sanchez-Calvo 2018 Free Radic Biol Med2018Sanchez-Calvo B, Cassina A, Mastrogiovanni M, Santos M, Kelley E, Rubbo H, Trostchansky A (2018) Improvement of mitochondrial function in steatohepatitis by olive oil consumption: role of nitro fatty acids. Free Radic Biol Med.Mouse
Meszaros 2018 Mt Med Hinxton2018High-resolution mitochondrial oxygen kinetics as diagnostic tool in Complex IV impairments.MouseHeart
Nervous system
Liver
Schlattner 2018 MiPschool Tromso B12018
Uwe Schlattner
Mitochondrial kinases: key players in respiratory control and energy transfer.
Chicco 2018 MiP2018b2018
Adam J Chicco
Defective cardiolipin remodeling and cardiac mitochondrial dysfunction: supercomplexes or just complex?
MouseHeart
Chicco 2018 MiP2018a2018
Adam J Chicco
Maternal aging increases granulosa cell mitochondrial ROS release and reduces oocyte OXPHOS-linked respiration: implications for embryo development.
HorseGenital
Garcia-Roves 2018 MiP2018b2018
Pablo Garcia-Roves
Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation
MouseSkeletal muscle
Porter 2018 MiP2018a2018
MiPsociety
Evidence of functional uncoupling protein 1 in the white adipose tissue of hypermetabolic humans.
HumanFat
Porter 2018 MiP2018b2018
MiPsociety
Skeletal muscle mitochondrial thermogenesis in hypermetabolic humans.
Wuest 2018 MiP2018b2018
Wuest Rob
The antibiotic doxycycline impairs cardiac mitochondrial and contractile function.
RatHeart
Other cell lines
Bovard 2018 IOC1342018Integrative determinants of oxygen uptake and biomolecular markers of exercise training.HumanSkeletal muscle
Janowska 2018 IOC1342018Mitochondrial targeted biofuels as countermeasures against chemical threats.HumanPlatelet
Stelfa 2018 MiP20182018
MiPsociety
Neuroprotective compound R-phenibut protects brain mitochondria against anoxia-reoxygenation damage in vitro.
RatNervous system
Ganetzky 2018 IOC1342018SUIT protocol development for zebrafish embryos.Fishes
Dubouchaud 2018 MiPschool Tromso2018
Dubouchaud Herve
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
MouseHeart
Krajcova 2018 ICO1342018Skeletal muscle bioenergetics in critically ill patients: effect of early rehabilitation on mitochondrial functions and insulin resistance during and 6 months after critical illness.HumanSkeletal muscle
Hoppel 2018 MiPschool Tromso D22018
Charles Hoppel
Mitochondrial function during ischemia/reperfusion injury.
Rat
Rabbit
Heart
Ravasz 2018 Abstract The evolving concept of mitochondria2018Vast pools of endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.MouseLiver
Horn 2018 Eur Heart J2018Horn P, Haschemi J, Scheiber D, Szendroedi J, Zweck E, Sun R, Luppa PB, Saeed D, Boeken U, Kelm M, Roden M, Boege F, Westenfeld R (2018) Sympathomimetic beta-1AR autoantibodies in patients after heart transplantation are associated with higher mitochondrial coupling efficiency. Eur Heart J.HumanHeart
Doerrier 2018 MiP2018b2018
Carolina Doerrier
Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.
Human
Mouse
Heart
Nervous system
Blood cells
HEK
Platelet
Komlodi 2018 AussieMit2018Komlodi T, Hunger M, Moore AL, Gnaiger E (2018) Electron transfer at the Q-junction: new perspectives from combined measurement of mitochondrial O2 flux, H2O2 flux, and coenzyme Q redox state. AussieMit 2018 Melbourne AU.MouseNervous system
Gnaiger 2018 AussieMit2018Komlodi Timea, Sobotka Ondrej, Doerrier Carolina, Gnaiger Erich (2018) Mitochondrial H2O2 production is low under tissue normoxia but high at in-vitro air-level oxygen pressure - comparison of LEAK and OXPHOS states. AussieMit 2018 Melbourne AU.Mouse
Saccharomyces cerevisiae
Heart
Nervous system
Huete-Ortega 2018 AlgaEurope20182018Huete-Ortega M, Komlodi T, Pranger F, Gnaiger E (2018) High-resolution respirometry: new perspectives for the study of microalgae bioenergetics and applications in biotechnology. AlgaEurope2018.Plants
Hoppel 2018 MiPschool Tromso D12018
Charles Hoppel
Two populations of muscle mitochondria: heart and skeletal muscle.
Rat
Dog
Other mammals
Heart
Skeletal muscle
MitoFit Open Seminar 2017-07-142017
MitoFit
Innsbruck AT, 2017 Jul 14. MitoFit Open Seminar on immune cell bioenergetics.
Investigating the role of mitochondria in healthy and psychopathological aging.
HumanBlood cells
Iglesias-Gonzalez 2017 MITOEAGLE Obergurgl2017
Javier Iglesias-Gonzalez
Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.
Holzknecht 2017 MiPschool Obergurgl2017
COST Action MitoEAGLE
Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook.
MouseHeart
Komlodi 2017 MiPschool Obergurgl2017
Timea Komlodi
Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production.
MouseNervous system
Sobotka 2017 MiPschool Obergurgl2017
Ondrej Sobotka
Reference protocols for ROS production measurements.
Karavyraki 2017 MiPschool Obergurgl2017
KaravyrakiMarilena.jpg
Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells.
Human
Siewiera 2017 MiPschool Obergurgl2017
Karolina Siewiera
Blood platelets as bioenergetic markers of brain damage in STZ-diabetes.
RatBlood cells
Platelet
Keppner 2017 MiPschool Obergurgl2017
COST Action MitoEAGLE
Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences.
Blood cells
O'Brien 2017 Abstract IOC1222017PPARα independent effects of nitrate supplementation on skeletal muscle mitochondrial function in hypoxia.MouseSkeletal muscle
Distefano 2017 MiPschool Obergurgl2017
Giovanna Distefano
Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects.
HumanSkeletal muscle
Garcia-Souza 2017 MiPschool Obergurgl2017
Luiz Garcia-Souza
Assessment of mitochondrial respiratory function in cryopreserved platelets.
HumanBlood cells
Platelet
Hellgren 2017 MiPschool Obergurgl2017
Kim Hellgren IMG 4885.JPG
Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production.
MouseHeart
Juhasz 2017 MiPschool Obergurgl2017
Juhasz L.jpg
Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.
RatLiver
Nogueras 2017 MiPschool Obergurgl2017
Lara Nogueras.jpg
Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients.
Blood cells
Krylova 2017 MiPschool Obergurgl2017
KrylovaT.jpg
High-resolution respirometry in diagnostic of mitochondrial complex I deficiency.
Endothelial;epithelial;mesothelial cell
Fibroblast
Garcia-Roves 2017 MiPschool Obergurgl2017
Garcia-RovesP.jpg
Mitochondrial fitness in skeletal muscle.
Skeletal muscle
Ukropec 2017 MITOEAGLE Obergurgl2017
COST Action MitoEAGLE
Could functional state of muscle mitochondria reflect exercise-induced changes in insulin sensitivity, glucose tolerance and cognitive performance in individuals with mild cognitive impairment?
Skeletal muscle
Phillips 2017 Cancer Research2017Abstract 3548: Hypoxia-induced Cystathionine-β-synthase (CBS) expression: impact on colonic epithelial cells metabolism, proliferation and migration.Endothelial;epithelial;mesothelial cell
Panajatovic 2017 IOC1242017Role of PGC-1α associated mitochondrial biogenesis in statin-induced myotoxicity.MouseSkeletal muscle
Krajcova 2017 MITOEAGLE Obergurgl2017
Krajcova A
Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.
Human
Waldauf 2017 MITOEAGLE Obergurgl2017
COST Action MitoEAGLE
Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates.
HumanSkeletal muscle
Pavlovic 2017 MITOEAGLE Obergurgl2017
Kasja picture.JPG
Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.
MouseSkeletal muscle
Nemec 2017 MiP20172017
Michal Nemec
Three-month exercise modulates skeletal muscle mitochondria function in patients with mild cognitive impairment.
HumanSkeletal muscle
Liebscher 2017 MiPschool Obergurgl2017
Gudrun Liebscher
The LAMTOR complex in regulation of fat metabolism.
MouseFat
Doerrier 2017 MiPschool C22017
DoerrierC.JPG
Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
Human
Mouse
Heart
Nervous system
HEK
Makrecka-Kuka 2017 MiP20172017
Marina Makrecka-Kruka
Heart, brain and kidneys: who will survive? Tissue-specific changes in mitochondrial function in the experimental model of endotoxemia.
MouseHeart
Nervous system
Kidney
Vaka 2017 Hypertension2017Abstract P265: Placental ischemia causes renal mitochondrial impairment in reduced uterine perfusion pressure rats.RatKidney
Genital
Calabria 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Age and frailty related changes in PBMCs mitochondrial function and whole body physiology.
HumanBlood cells
Shabalina 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Control of UCP1 activity in brown fat mitochondria.
MouseFat
Wuest 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Mitochondrial Complex I function in heart failure: different angles to analyze mitochondrial function.
RatHeart
Sobotka 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
The effect of 24 weeks of high-fat and high-cholesterol diet on rat liver mitochondria. Sobotka_Presentation
RatLiver
Vendelin 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Most of mitochondrial voltage-dependent anion channels are closed in rat cardiomyocytes
RatHeart
Scatena 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Mitochondria and cancer stem cells in hepatocarcinoma. An illustrative example of a tangled methodological approach.
Liver
Fromme 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Source depot and dietary status influence oxidative phosphorylation capacity in permeabilized, mature adipocytes. Fromme_Presentation
MouseFat
Hartmann 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Mitochondrial respiration of isolated peripheral blood mononuclear cells in an experimental porcine brain injury model.
Human
Pig
Blood cells
Komlodi 2017 Abstract MITOEAGLE Barcelona2017
COST Action MitoEAGLE
Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Guinea pig
Mouse
Nervous system
Kidney
Heart
Liver
Michalak 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Mitochonrial respiration in intact peripheral blood mononuclear cells in patients with extrapyramidal syndromes.
HumanBlood cells
Ost 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Novel multivariate biomarkers of age-dependent sarcopenia: A blood based bioenergetics & cytokine profiling approach.
Human
Mouse
Blood cells
Arandarcikaite 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Age-related responses of brain mitochondria to ischemic insult. Arandarcikaite_Presenation
RatNervous system
Siewiera 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
The effect of metformin on blood platelet bioenergetics and platelet function.
HumanBlood cells
Platelet
Aasum 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Mitochondrial function in the diabetic heart – effect of an acute fat-load.
MouseHeart
Meszaros 2017 MiPschool Obergurgl2017
Andras Meszaros
(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.
MouseLiver
Nervous system
Kidney
Nemec 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Functional state of mitochondria in patients with preclinical cognitive deficit.
HumanSkeletal muscle
Tura-Ceide 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Endothelial cells as a model for metabolic shift in chronic thromboembolic pulmonary hypertension.
Endothelial;epithelial;mesothelial cell
Bufe 2017 TRACT PhD project abstract2017Metabolic profiles in normal, dysplastic and cancerous oral cells.HumanOther cell lines
Gnaiger 2017 Abstract EUROMIT2017 Cologne2017
EUROMIT2017
Again not a Warburg effect - mitochondrial function in primary prostate cancer.
HumanEndothelial;epithelial;mesothelial cell
Genital
Fibroblast
Laner 2017 Abstract EUROMIT2017 Cologne2017
EUROMIT2017
K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Human
Han 2017 Abstract IOC1222017Retinal mitochondria respiration defects precede hyperglycemia onset in type 2 diabetes.RatNervous system
Skolik 2017 Abstract IOC1222017What can we learn from different sugars as substrates for cancer cells?HumanLiver
Karavyraki 2017 Abstract IOC1222017Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells.HumanEndothelial;epithelial;mesothelial cell
Truu 2017 Abstract IOC1222017Bioenergetics of colorectal cancer.Endothelial;epithelial;mesothelial cell
Amick 2017 MiPschool Obergurgl2017
Amick picture.jpg
Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates.
Other mammalsNervous system
Collins 2017 MiPschool Obergurgl2017
COST Action MitoEAGLE
The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics.
Markova 2017 MiPschool Obergurgl2017
Michaela Markova
Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase.
RatHeart
Chang 2017 FASEB J2017Effects of cycling exercise on mitochondrial function and efficacy of peripheral blood mononuclear cells under hypoxic condition in sedentary men.Blood cells
Hoppel 2017 MiP20172017
Charles Hoppel
Pathways of mitochondrial fatty acid oxidation. Hoppel_Presentation
RatLiver
Irving 2017 MiP20172017
Brian Irving
Impact of acute exercise on PBMC respiratory function and methodological considerations.
Blood cells
Iyer 2017 MiP20172017
Iyer Shilpa
Bioenergetic profiling of patient derived human fibroblasts for mitochondrial diseases. Iyer_Presentation
HumanFibroblast
Komlodi 2017 MiP20172017
Timea Komlodi
H2O2 production under hypoxia in brain and heart mitochondria: does O2 concentration matter?
MouseHeart
Nervous system
Meszaros 2017 MiP20172017
Andras Meszaros
Mitochondrial oxygen kinetics as a sensitive diagnostic tool to determine apparent cytochrome c oxidase excess capacity.
MouseNervous system
Liver
Kidney
Nedergaard 2017 MiP20172017
Jan Nedergaard
Creatine effect in mitochondria from different tissues.
MouseHeart
Liver
Fat
Sumbalova 2017 MiP2017 WG42017
Zuzana Sumbalova
Purity of blood cell fractions in respirometric studies: peripheral blood mononuclear cells and platelets.
Blood cells
Platelet
Sobotka 2017 MiP20172017
Ondrej Sobotka
Metabolic changes in rat liver mitochondria during the development of liver steatosis.
RatLiver
Sumbalova 2017 MiP20172017
Zuzana Sumbalova
The effect of lifestyle on respiration of peripheral blood mononuclear cells and platelets.
Blood cells
Platelet
Aasander Frostner 2017 MiP20172017
Åsander Frostner Eleonor
Cell-permeable succinate and malonate as research tools. Aasander Frostner_Poster
HumanHeart
Liver
Blood cells
Fibroblast
Larsen 2017 MiP2017 WG22017
Steen Larsen
The effect on respiratory capacity using different respiration buffers.
HumanSkeletal muscle
Calabria 2017 MiP20172017
Elisa Calabria
Age and frailty related changes in PBMCs mitochondrial function and whole body physiology.
HumanBlood cells
Wu 2017 FASEB J2017Effects of eccentric and concentric cycling exercise regimens on hypoxia-mediated mitochondrial bioenergetics of platelets in sedentary males.HumanBlood cells
Platelet
Garcia-Souza 2017 MiP20172017
Luiz Garcia
Short-term acclimatization to moderate altitude does not affect respiration of peripheral blood mononuclear cells and platelets.
HumanBlood cells
Platelet
Wu 2017b FASEB J2017Effects of interval and continuous exercise regimens on platelet mitochondrial bioenergetics under hypoxic stress.HumanBlood cells
Platelet
Lin 2017 FASEB J2017Mitochondrial respiration is fiber-type specific in skeletal muscles.RatSkeletal muscle
King 2017 ANDA20172017Improving skeletal muscle mitochondrial turnover to combat insulin resistance.MouseSkeletal muscle
Chowdhury 2017 Blood2017Importance of mitochondrial metabolism as a selective therapeutic approach in chronic lymphocytic leukemia patients.HumanLymphocyte
Muguiz 2017 J Cachexia Sarcopenia Muscle2017Chronic tobacco smoke exposure induces aryl hydrocarbon receptor-dependent neuromuscular junction degeneration.MouseSkeletal muscle
Schilling 2017 J Mol Cell Cardiol2017Loss of caveolin-1 alters cardiac mitochondrial function and increases susceptibility to stress.MouseHeart
White 2017 J Anim Sci2017Influence of temperament on skeletal muscle mitochondrial capacity of Brahman cows.BovinesSkeletal muscle
Cizmarova 2017 MiP20172017
Beate Cizmarova
PBMC cryopreservation and evaluation for functional mitochondrial diagnosis.
HumanBlood cells
Cizmarova 2017 MITOEAGLE Obergurgl2017
Beata Cizmarova
High-resolution respirometry and viability of cryopreserved blood cells.
Blood cells
Platelet
Cizmarova 2017 Abstract MITOEAGLE Barcelona2017
COST Action MitoEAGLE
Optimization of cryopreservation of human peripheral blood mononuclear cells and platelets for high-resolution respirometry.
HumanBlood cells
Platelet
Murray 2017 Abstract MITOEAGLE Barcelona2017
COST Action MitoEAGLE
Metabolic adaptation to high altitude in Himalayan Sherpas.
HumanSkeletal muscle
Gnaiger 2017 Abstract MitoEAGLE Barcelona2017
COST Action MitoEAGLE
Quality first: a paradigm shift in mt-respiratory control towards global connection.
Human
Mouse
Heart
Genital
Doerrier 2017 Abstract MitoEAGLE Barcelona2017
COST Action MitoEAGLE
SUIT reference protocol for comparative mitochondrial physiology.
Human
Mouse
Heart
Nervous system
HEK
Lemieux 2017 MiP20172017
Helene Lemieux
Compounding effects of age and sexual dimorphism on cardiac mitochondrial function in type 2 diabetes.
RatHeart
Scheiber 2017 Europ Heart J2017High-resolution respirometry in human endomyocardial biopsies to assess myocardial mitochondrial function.HumanHeart
Nakajima 2017 Europ Heart J2017Mitochondrial dysfunction in epicardial adipose tissue; possible role in progression of coronary artery disease.HumanFat
Labieniec-Watala 2017 MiP20172017
Magda Labieniec-Watala
Lack of the effect of low metformin concentrations on the response of breast cancer cell mitochondria to radiotherapy under conditions of the in vitro experimental hyperglycemia. Labieniec-Watala_Presentation
HumanGenital
Muntean 2017 MiP20172017
Danina Mundean
Impairment of platelet mitochondrial respiration in metabolic syndrome: A pilot study.
HumanBlood cells
Platelet
Garcia-Roves 2017 MiP20172017
Pablo Garcia-Roves
Mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. MitoEAGLE WG2 pilot study. Garcia-Roves_Presentation
MouseSkeletal muscle
Siewiera 2017 MiP20172017
Karolina Siewiera
Changes in blood platelet and brain mitochondrial respiration during short and long-lasting STZ-induced diabetes.
RatNervous system
Blood cells
Platelet
Keppner 2017 MiP20172017
MiPsociety
Mitochondrial function of peripheral blood mononuclear cells (PBMCs) in subjects with metabolic syndrome.
HumanBlood cells
Endlicher 2017 MiP20172017
Rene Endlicher
Age-related changes in isolated mitochondria from rat liver.
RatLiver
Alan 2017 MiP20172017
Alan Lukas
Role of MLQ protein in the structure and function of mammalian F1FO ATP-synthase.
HumanKidney
Brazdova 2017 MiP20172017
Brazdova Andrea
Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production.
Fat
Karabatsiakis 2017 MiP20172017
MiPsociety
The involvement of mitochondria in chronic low-grade inflammation associated with maltreatment experiences in childhood. Karabatsiakis_Presentation
HumanBlood cells
Klepinin 2017 MiP20172017
MiPsociety
Novel method to study the role of the adenylate kinase network in health and disease.
Human
Rat
Heart
Stem cells
Kovalcikova 2017 MiP20172017
Kovalcikova Jana
Mitochondrial protein TMEM70: key role in the biogenesis of ATP synthase verified in a mouse knockout model.
MouseHeart
Liver
Hofstee 2017 Placenta2017Maternal selenium deficiency in mice alters placental function, reduces foetal glucose concentration and impairs foetal growth.MouseGenital
Markova 2017 MiP20172017
Michaela Markova
Porcine sepsis and associated myocardial depression.
PigHeart
Michalak 2017 MiP20172017
MiPsociety
The effect of anticoagulants on mitochondrial respiration in intact peripheral blood mononuclear cells.
HumanBlood cells
Ounpuu 2017 MiP20172017
Ljudmila Ounpuu
The role of dietary fibers in the energy metabolism of human colon cancer cells.
Human
Pajuelo-Reguera 2017 MiP20172017
David Pajuelo-Reguera
COX4-1/COX4-2 cell knock-out/knock-in models for the study of cytochrome c oxidase regulation.
HumanHEK
Periasamy 2017 MiP20172017
MiPsociety
Targeting skeletal muscle energetics to control obesity and diabetes.
Mouse
Puurand 2017 MiP20172017
MiPsociety
Cellular phosphotransfer networks as a target of bioenergetic research – methods of oxygraphic study.
Rybacka-Mossakowska 2017 MiP20172017
MiPsociety
Mitochondrial respiration in intact peripheral blood mononuclear cells in multiple sclerosis patients.
HumanBlood cells
Shabalina 2017 MiP20172017
Irina Shabalina
In UCP1-ablated mice, prolonged cold exposure promotes mitochondrial dysfunction, apoptosis and inflammation in brown adipose tissue, and accumulation of visceral obesogenic fat.
MouseFat
Truu 2017 MiP20172017
Laura Truu
Bioenergetic comparison of human colorectal and breast cancer clinical patients.
Human
Urban 2017 MiP20172017
MiPsociety
Kinetics of inhibition of energy metabolism pathways by propofol in human skeletal muscle homogenates.
HumanSkeletal muscle
Boyle 2017 MiP20172017
John Boyle
Type 2 diabetes causes systemic skeletal muscle complex I mitochondrial dysfunction in chronic heart failure patients.
HumanSkeletal muscle
Doerrier 2017 MiP2017 C12017
Carolina Anneliese Doerrier
Effects of warm ischemia on cardiac mitochondria to detect specific targets by high-resolution respirometry (HRR)
MouseHeart
Doerrier 2016 Abstract MitoFit Science Camp 20162016Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.Human
Mouse
Heart
Blood cells
HEK
Platelet
Volani 2016 Abstract MitoFit Science Camp 20162016Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.Mouse
Rat
Liver
Blood cells
Lymphocyte
Gnaiger 2016 Abstract EBEC Riva del Garda 20162016MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Krumschnabel 2016b Abstract MitoFit Science Camp 20162016O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry.HumanKidney
HEK
Marcinek 2016 Abstract MitoFit Science Camp 20162016Targeting mitochondrial redox stress reveals two phases for reversal of mitochondrial dysfunction in aged mouse skeletal muscle.MouseSkeletal muscle
Krako 2016 Abstract MitoFit Science Camp 20162016Conformational targeting of amyloid β oligomers inside endoplasmic reticulum rescues mitochondrial deficits in 7PA2 cells.Other mammalsGenital
CHO
Bezuidenhout 2016a Abstract MitoFit Science Camp 20162016Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.MouseSkeletal muscle
Bezuidenhout 2016b Abstract MitoFit Science Camp 20162016Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers.MouseSkeletal muscle
Lamberti 2016 Abstract MitoFit Science Camp 20162016Development of a reference sample for HRR.HumanKidney
HEK
Krumschnabel 2016a Abstract MitoFit Science Camp 20162016O2k-Protocols: Mitochondrial preparations for HRR.MouseHeart
Hoppel 2016c Abstract MitoFit Science Camp 20162016Mitochondrial respiration in permeabilized skin fibroblasts.HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Kane 2016 Abstract MitoFit Science Camp 20162016Effects of inhibiting myosin-ATPase on mitochondrial respiratory capacity in permeabilized skeletal muscle.RatSkeletal muscle
Sumbalova 2016a Abstract MitoFit Science Camp 20162016Optimizing strategies on the malate concentration in SUIT protocols.RatNervous system
Laner 2016 Abstract MitoFit Science Camp 20162016OXPHOS and ET-capacity in permeabilized fibers of canine superathletes. Analysis of HRR data presenting unexpected challenges.DogSkeletal muscle
Louw 2016 Abstract FASEB J2016Exercise limits loss of respiratory function seen with doxorubicin treatment without affecting muscle function.MouseSkeletal muscle
Murphy 2016 Abstract FASEB J2016Metformin limits loss of mitochondrial respiration seen with doxorubicin treatment without affecting muscle function.MouseSkeletal muscle
Sumbalova 2016b Abstract MitoFit Science Camp 20162016Human blood cells: isolation and HRR.HumanBlood cells
Lymphocyte
Platelet
Bird 2016 Abstract IOC1152016High-resolution respirometry for the diagnosis of mitochondrial disease.HumanSkeletal muscle
Liver
Fibroblast
Gnaiger 2016 Abstract SFRR Australasia 20162016Facts and artefacts in measurements of H2O2 production under hypoxia.Saccharomyces cerevisiae
Schaefer 2016 Abstract ADFLIM 20162016ADFLIM in AD research –imaging mitochondrial function in Alzheimer´s diseaseNervous system
Uribe-Alvarez 2016 Abstract MitoFit Science Camp 20162016In Staphylococcus epidermidis, oxygen variations promote differential expression of respiratory enzymes that constitute possible therapeutic targets.Eubacteria
Sparagna 2016 Abstract IOC1092016Sparagna GC (2016) Measuring cardiac mitochondrial function in pediatric patients before and after implantation of a left ventricular assist device. Mitochondr Physiol Network 21.01.HumanHeart
Soendergaard 2016 Abstract IOC1092016Soendergaard SD (2016) Acute exposure of human muscle fibers to EPO or Actovegin has a marked effect on the mitochondrial respiratory capacity. Mitochondr Physiol Network 21.01.HumanSkeletal muscle
Gnaiger 2016 Abstract UMDF20162016Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells.HumanEndothelial;epithelial;mesothelial cell
Genital
Other cell lines
Fibroblast
Chicco 2016a Abstract MitoFit Science Camp 20162016Oxygen dependence of H2O2 release from skeletal muscle and cardiac mitochondria: influence of sample preparation.MouseHeart
Skeletal muscle
Chicco 2016b Abstract MitoFit Science Camp 20162016OXPHOS coupling efficiency of permeabilized muscle fibers predicts metabolic efficiency of subjects exercising at 5260 m.HumanSkeletal muscle
Schaefer 2016 Abstract MitoFit Science Camp 20162016Prominent role of amyloid beta and its intracellular localization in Alzheimer´s disease associated mitochondrial dysfunction.HumanNervous system
HEK
Osiki 2016 Abstract MitoFit Science Camp 20162016Suitability of octanoylcarnitine & malate for assessment of beta oxidation capacity by respirometry in aconitase-inhibited samples.RatSkeletal muscle
Votion 2016 Abstract MitoFit Science Camp 20162016OXPHOS capacities correlate with racing performance and indicate risk of developing exercise-induced myopathy.HorseSkeletal muscle
Madlala 2016 Abstract MitoFit Science Camp 20162016Fructose-induced defects in selected mitochondrial enzymes is detected by respirometry using glutamate&malate but not pyruvate&malate substrates.HumanLiver
Hellgren 2016 Abstract Proceedings of The Physiological Society2016Sexual dimorphism in cardiac mitochondria following intrauterine hypoxia.Nervous system
Heart
Morales-Garcia 2016 Abstract MitoFit Science Camp 20162016Respiratory deficiencies in isolated mitochondria from a Δ-shy1 S. cerevisiae strain.Saccharomyces cerevisiae
Maarman 2016 Abstract MitoFit Science Camp 20162016Melatonin rescues uric acid-induced impairment of respiration in myotubes.MouseSkeletal muscle
Other cell lines
Krajcova 2016 Abstract MitoFit Science Camp 20162016Mitochondrial pathogenesis of propofol infusion syndrome in an in vitro model of human skeletal muscle.HumanSkeletal muscle
Chicco 2016c Abstract MitoFit Science Camp 20162016Investigating the mechanism of cardiac mitochondrial respiratory impairment in Barth Syndrome.MouseHeart
Markova 2016 Abstract MitoFit Science Camp 20162016Porcine hearts samples preparation: PBI-Shredder or saponin?PigHeart
Calzia 2016 Abstract MitoFit Science Camp 20162016Mitochondrial respiration shows tissue- and strain-specific aging in short- and long-lived N. furzeri strains.FishesHeart
Skeletal muscle
Nervous system
Liver
Burtscher J 2016 Abstract MitoFit Science Camp 20162016Oxidative phosphorylation in the healthy and epileptic mouse brain.MouseNervous system
Garcia-Roves 2016b Abstract MitoFit Science Camp 20162016Technical perspective of high-resolution respirometry in permeabilized skinned muscle fibers from different mouse models.MouseSkeletal muscle
Hoppel 2016b Abstract MitoFit Science Camp 20162016Comparison of permeabilized skeletal muscle fibers or isolated mitochondria for the detection of oxidative phosphorylation defects.HumanSkeletal muscle
Zatarain 2016 Abstract Cancer Research2016Abstract 4276: Cystathionine-β-synthase overexpression increases cell proliferation, migration, bioenergetics and tumorigenesis in a non-tumorigenic colorectal cancer (CRC) cell line.Human
Mouse
Endothelial;epithelial;mesothelial cell
Buck 2016 Abstract J Neurol Neurosurg Psychiatry2016B30 Integrated mitochondrial function in human fine-needle muscle biopsies of huntington’s disease mutation carriers and in tissues of HdhQ111 mice.MouseHeart
Skeletal muscle
Nervous system
Liver
Davies 2016 Abstract Proceedings of The Physiological Society2016Development of mitochondrial function in the cortex and cerebellum of the ovine fetus.BovinesNervous system
Krizova 2016 Abstract IOC1162016Krizova J, Macakova M, Bohuslavova B, Klima J, Ellederova Z, Zeman J, Motlik J, Hansikova H (2016) Complex I-dependent respiration decline is a marker of Huntington`s disease in spermatozoa of transgenic minipig model. Mitochondr Physiol Network 21.11PigGenital
Volani 2016 Abstract Mito Xmas Meeting Innsbruck2016Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.MouseLiver
Schoepf 2016 Abstract Mito Xmas Meeting Innsbruck2016Mitochondrial function in primary prostate cancer.Human
Doerrier 2016b Abstract Mito Xmas Meeting Innsbruck2016Searching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.MouseHeart
Krumschnabel 2016 Abstract Mito Xmas Meeting Innsbruck2016Establishment of a reference sample for high-resolution respirometry.HumanHEK
Garcia-Souza 2016 Abstract Mito Xmas Meeting Innsbruck2016Assessment of fatty acid oxidation in mouse brain and liver mitochondria.Nervous system
Liver
Gnaiger 2016 Abstract Mito Xmas Meeting Innsbruck2016The world as a laboratory: exploring mitochondrial fitness.HumanSkeletal muscle
Laner 2016 Abstract Mito Xmas Meeting Innsbruck2016OXPHOS and ET capacity in permeabilized fibers of canine superathletes.DogSkeletal muscle
Sumbalova 2016 Abstract Mito Xmas Meeting Innsbruck2016Methods for evaluation of mitochondrial membrane potential with multi-sensor high-resolution respirometry: potentiometry vs fluorometry.MouseNervous system
Schoepf 2016 Abstract Androgens 20162016Mitochondrial function and mitochondrial heteroplasmy levels differ between benign and malignant prostate tissue.Genital
Komlodi 2016 Abstract IOC1162016Komlodi T, Geibl F, Sassani M, Adam-Vizi V, Tretter L (2016) The effect of ΔΨmt and ΔpH on mitochondrial reactive oxygen species production - A comparative study using mitochondria isolated from different mammalian tissues. Mitochondr Physiol Network 21.11Guinea pigHeart
Skeletal muscle
Nervous system
Nielsen 2016 Abstract IOC1162016Nielsen B, Woertwein G, Cejvanovic V, Hansen AR, Weimann A, Bjerring PN, Poulsen HE, Joergensen MB (2016) The function of mitochondria and oxidative stress after antidepressants treatment in rats. Mitochondr Physiol Network 21.11RatNervous system
Sobotka 2016 Abstract IOC1162016Sobotka O, Kucera Otto, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11RatLiver
Morato 2016 Abstract IOC1162016Morato L, Guillot de Suduiraut MI, Grosse J, Zanoletti O, Riccio O, Fournier C, Sandi C (2016) Impaired mitochondrial function mediates early life stress-induced depression. Mitochondr Physiol Network 21.11Mouse
Weber 2016 Abstract Mito Xmas Meeting Innsbruck2016Loss of PTEN in prostate cancer cells leads to a switch to succinate-mediated mitochondrial respiration associated with increased expression of NaDC3 and HIF-1alpha.Human
Mouse
Genital
Ali 2015 Abstract MiP20152015Mitochondrial function and ROS homeostasis in young mouse heart and brain: the sex factor!MouseHeart
Nervous system
Laner 2015 Abstract MiPschool Greenville 20152015Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.DogSkeletal muscle
Doerrier 2015 Abstract MiPschool Greenville 20152015"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.MouseHeart
Boyle 2015 Abstract MiP20152015Kv1.3 channels in mitochondria: Are they important in cellular proliferation?HumanEndothelial;epithelial;mesothelial cell
HEK
Zhang 2015 Abstract MiPschool Greenville 20152015Skeletal muscle NAMPT overexpression prevents mitochondrial dysfunction during hindlimb unloading induced muscle atrophy.MouseSkeletal muscle
Amoedo 2015 Abstract MiP20152015The energy requirement of metastatic cells.Mouse
Rat
Other cell lines
Blecha 2015 Abstract MiP20152015Modulation of mitochondrial electron transport chain activity differentially regulates cell death in proliferating and quiescent cells.
Calzia 2015 Abstract MiP20152015Mitochondrial respiration in homogenized small tissue biopsies from the M. Vastus lateralis of patients with Huntington's Disease before and after cycling exercise.HumanSkeletal muscle
Kokassaar 2015 Eesti Arst2015Erinevused wolframiinidefitsiidiga ja normaalsete hiirte lihaste hingamisahelate komplekside aktiivsuses.Skeletal muscle
Hoppel 2015 Abstract MiP20152015Effects of ultramarathon performance on mitochondrial respiration in human platelets.HumanBlood cells
Platelet
Gnaiger 2015 Abstract MiP20152015Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.HumanHEK
Karabatsiakis 2015 Abstract MiP20152015Mitochondrial respiration of peripheral blood mononuclear cells in patients with borderline personality disorder.HumanBlood cells
Rohlena 2015 Abstract MiP20152015Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation.HumanOther cell lines
Kaambre 2015 Abstract MiP20152015Quantitative characterization of respiratory parameters of human colorectal and breast cancer clinical material.HumanEndothelial;epithelial;mesothelial cell
Laner 2015 Abstract MiP20152015Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.DogSkeletal muscle
Weidgang 2015 Abstract MiP20152015Mitochondrial respiration in homogenized biopsies from kidney, liver, heart and diaphragm from mice after blunt thoracic trauma and hemorrhagic shock. Effects of a novel hydrogen sulfide donor AP39.MouseHeart
Skeletal muscle
Liver
Kidney
Sleiman 2015 Abstract MiP20152015Mitochondrial respiration in sequential biospies from skeletal muscles during hemorrhagic shock and over the course of 48h of reperfusion in pigs.PigSkeletal muscle
Shevchuk 2015 Abstract MiP20152015Analysis of energy fluxes in colorectal cancer saponin skinned tissues and Caco-2 cells.HumanEndothelial;epithelial;mesothelial cell
Madlala 2015 Abstract MiPschool Cape Town 20152015Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-β1.HumanLiver
Other cell lines
Brown 2015 Abstract MiPschool Cape Town 20152015Protection of post-ischemic mitochondrial bioenergetics by targeting cardiolipin-dependent membrane fluidity.RatHeart
Smenes 2015 Abstract IOC1002015Smenes BT, Baekkerud FH, Hassel E, Wohlwend M, Slagsvold KH, Rognmo O, Wahba A (2015) Mitochondrial function in patients exercising prior to coronary surgery – A single blinded randomized controlled trial. Mitochondr Physiol Network 20.01.HumanSkeletal muscle
Abdel-Rahman 2015 Abstract MiPschool Cape Town 20152015Assessment of NADPH-dependent oxygen consumption and hydrogen peroxide production by high-resolution respirometry and EPR spectroscopy.Human
Mouse
Nervous system
Gnaiger 2015 Abstract MiPschool Cape Town 20152015The functional design of the electron transfer system (ETS) and mitochondrial respiratory control.
Laner 2015 Abstract MiPschool Cape Town 20152015The Oroboros Oxygraph-2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis.Mouse
Saccharomyces cerevisiae
Heart
Ost 2015 Abstract IOC1002015Ost M (2015) “Mitokines” and the organismal role of mitochondrial function in energy homeostasis & metabolism. Mitochondr Physiol Network 20.01.MouseSkeletal muscle
Fibroblast
Bezuidenhout 2015 Abstract MiPschool Cape Town 20152015A study of the effects of fructose feeding & exercise on SIRT 3 regulation in skeletal muscle.Rat
George 2015 Abstract MiPschool Cape Town 20152015Regulation of LCAD and SIRT3 activities by NAD+ in skeletal muscle of fructose-fed rats.RatSkeletal muscle
Maarman 2015 Abstract MiPschool Cape Town 20152015Characterisation of mitochondrial function in a model of pulmonary hypertension-induced right ventricular failure.RatHeart
Sheldon 2015 Abstract MiPschool Greenville 20152015eNOS is required to preserve hepatic mitochondrial function in western diet-induced nonalcoholic fatty liver disease.MouseLiver
Ojuka 2015 Abstract MiPschool Cape Town 20152015Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation.
Ali 2015 Abstract MiPschool Cape Town 20152015Early gender-related dimorphism in heart and brain mitochondria function and ROS dynamics.MouseHeart
Nervous system
Mussulini 2015 Abstract MiPschool London2015Changes of brain substrates preference and metabolism during seizure induced by pentylenetetrazole in adult zebrafish.ZebrafishNervous system
Pettersen 2015 Abstract MiPschool London 20152015Metabolic adjustments after reversible induction of mitochondrial biogenesis via AMPK/NRF1 in HeLa cells.
Ehinger 2015 Abstract MiPschool London 20152015Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease.HumanHeart
Blood cells
Fibroblast
Hoppel 2015 Abstract MiPschool London 20152015Human blood cell types as study models of mitochondrial respiration and H2O2 production.HumanBlood cells
Logan 2015 Abstract MiPschool London 20152015Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling.HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Hill 2015 Abstract MiPschool London 20152015A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis.MouseLiver
Bhattarai 2015 Abstract MiPschool Greenville 20152015Exercise improves whole-body and skeletal muscle oxidative capacity in burned children.HumanSkeletal muscle
Doerrier 2015 Abstract MiP20152015Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.MouseHeart
Coelho 2015 Abstract Thyroid Cancer2015AMPK overactivation in BCPAP tumor cells induces cell death through increased reactive oxygen species (ROS).
Chang 2015 Abstract EB20152015Different effects of interval and continuous exercise regimens on capacity of mitochondria oxidative phosphorylation in lymphocyte.HumanMacrophage-derived
Devaux 2015 Abstract MiP20152015Mitochondrial complexes I and II behave differently in two anoxia-tolerant species: adaptive mitochondrial plasticity may be related to the ability to undergo metabolic depression.FishesNervous system
Lindquist 2015 Abstract IOC1062015Alteraas EK, Lindquist C, Berge RK, Bjorndal B (2015) OXPHOS capacity in mouse liver altered by modified fatty acids that inhibit or stimulate beta-oxidation. Mitochondr Physiol Network 20.10.MouseLiver
Volani 2015 Abstract IOC1062015Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.Human
Mouse
Heart
Liver
Blood cells
Lymphocyte
Galina 2015 Abstract MiP20152015High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles.RatSkeletal muscle
Kovalcikova 2015 Abstract MiP20152015Derangements of myocardial mitochondrial function in patients with end-stage heart failure is associated with reduced endonuclease G.HumanHeart
Tepp 2015 Abstract MiP20152015Changes in energy transfer regulation during development and aging.Heart
Sumbalova 2015 Abstract MiP20152015High-resolution measurement of mitochondrial membrane potential and respiration – comparison of potentiometric and fluorometric methods.MouseNervous system
Renshaw 2015 Abstract MiP20152015Mitochondrial responses to thermal stress: is the ability to withstand anoxia-induced stress associated with cross-tolerance to thermal stress?FishesNervous system
Tretter 2014 Abstract MiP20142014Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia.Guinea pigNervous system
Bristot 2014 Abstract MiP20142014High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations.HumanFibroblast
Brown DA 2014 Abstract MiP20142014The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes.RatHeart
Burtscher 2014 Abstract MiP20142014Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain.MouseNervous system
Coen 2014 Abstract MiP20142014Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery.HumanSkeletal muscle
MacDonald 2014 Abstract MiP20142014The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle.RatHeart
Nervous system
Liver
Kidney
Dohlmann 2014 Abstract MiP20142014Mitochondrial adaptations to high-intensity training in young and elderly men and women.HumanSkeletal muscle
HeLa
Fibroblast
Meszaros 2014 Abstract MiP20142014Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs.Rat
Guinea pig
Bresciani Martins de Andrade 2014 Abstract MiP20142014Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption.Fat
Galina 2014 Abstract MiP20142014Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system.RatNervous system
Power 2014 Abstract MiP20142014The hot heart: cardiac mitochondrial energetics during hyperthermia.RatHeart
Figueira 2014 Abstract MiP20142014Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity.RatHeart
Skeletal muscle
Nervous system
Liver
Rodrigues 2014 Abstract MiP20142014Bioenergetics’ traits of tongue cancer metastatic cells.MouseLymphocyte
Schoepf 2014 Abstract MiP20142014OXPHOS analysis in small prostate biopsies.HumanGenital
Sparks 2014 Abstract MiP20142014NAMPT remodels substrate metabolism in skeletal muscle.MouseSkeletal muscle
Spendiff 2014 Abstract MiP20142014Lessons from the master athlete: mitochondrial contributions to aging.HumanSkeletal muscle
Sumbalova 2014 Abstract MiP20142014Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.RatNervous system
Liver
Nogueira 2014 Abstract IOC 2014-04 Schroecken2014Nogueira NP, Baldow QCS, Costa DSS, Domingos J, Laranja GAT, Costa PRR, Dias AG, Paes MC (2014) The effect of nitrones upon clinically relevant forms of Trypanosoma cruzi. Mitochondr Physiol Network 19.02.Mouse
Protists
Macrophage-derived
Pecina 2014 Abstract MiP20142014Manifestation of mitochondrial disorders of nuclear origin in lymphocytes.HumanBlood cells
Lymphocyte
Paju 2014 Abstract MiP20142014Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts.HumanSkeletal muscle
Neufer 2014 Abstract MiP20142014Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O.MouseSkeletal muscle
Nagy 2014 Abstract MiP20142014Investigation of the energy metabolism of microglial cells.HumanNervous system
Mracek 2014 Abstract MiP20142014Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13.HumanHeart
Holloway 2014 Abstract MiP20142014Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions.MouseFat
Legkun 2014 Abstract IOC 2014-04 Schroecken2014Legkun G, Motovilov K (2014) Investigation on alternative mechanism of electron transport in the respiratory system. Mitochondr Physiol Network 19.02.RatLiver
Paes 2014 Abstract IOC 2014-04 Schroecken2014Paes MC, Saraiva FMS, Nogueira NP, Laranja GAT, Coelho MGP, Oliveira MF (2014) Heme increases mitochondrial membrane potential and ROS production in Trypanosoma cruzi epimastigotes. Mitochondr Physiol Network 19.02.Protists
Mendonca 2014 Abstract IOC 2014-04 Schroecken2014Mendonca AP, Rodrigues MF, Amoedo ND, Oliveira MF (2014) Effects of iron on mitochondrial physiology of central nervous system cell lines. Mitochondr Physiol Network 19.02.Nervous system
Other cell lines
Neuroblastoma
Borutaite 2014 Abstract MiP20142014Controversies regarding cytochrome c test for mitochondrial membrane integrity.RatHeart
Nervous system
Maedo 2014 Abstract IOC 2014-04 Schroecken2014Maedo K, Kaldma A, Planken A, Klepinin A, Chekulayev V, Varikmaa M, Tepp K, Chevchuk I, Kaambre T (2014) Regulation of mitochondrial respiration in human colorectal cancer cells in situ: the possible role of beta-tubulins. Mitochondr Physiol Network 19.02.HumanEndothelial;epithelial;mesothelial cell
Perry 2014 Abstract MiP20142014Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibers.HumanSkeletal muscle
Agrimi 2014 Abstract IOC 2014-04 Schroecken2014Agrimi G, Mena MC, Izumi K, Pisano I, Germinario L, Fukuzaki H, Palmieri L, Blank LM, Kitagaki H (2014) Increased mitochondrial pyruvate dissimilation in sake yeast. Mitochondr Physiol Network 19.02.Saccharomyces cerevisiae
Wagenaars 2014 Abstract IOC 2014-04 Schroecken2014Wagenaars J, Willems PHGM, Koopman WJ (2014) Oxygen consumption in OXPHOS-deficient cells. Mitochondr Physiol Network 19.02.Human
Mouse
Skeletal muscle
Fibroblast
Dhandapani 2014 Abstract IOC 2014-04 Schroecken2014Dhandapani PK, Dufour E, Jacobs HT, Szibor M (2014) Alternative oxidase-based therapy for heart failure. Mitochondr Physiol Network 19.02.MouseHeart
Alberici 2014 Abstract MiP20142014Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism.RatSkeletal muscle
Ali 2014 Abstract MiP20142014Oxygen-consuming and ROS-producing activities in synaptosomes.Nervous system
Amoedo 2014 Abstract MiP20142014The metabolic panorama during tumor progression towards malignancy.Other cell lines
Jezek 2014 Abstract MiP20142014Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.Other cell lines
Hahn 2014 Abstract MiP20142014Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases.HumanSkeletal muscle
Fibroblast
Harrison 2014 Abstract MiP20142014The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia.Rat
Bovines
Heart
Hepple 2014 Abstract MiP20142014Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention.HumanSkeletal muscle
Herbst 2014 Abstract MiP20142014Analysis of mitochondrial function in multiple brain regions through in situ permeabilization.MouseNervous system
Hickey 2014 Abstract MiP20142014Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart.RatHeart
Horscroft 2014 Abstract MiP20142014Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch?RatHeart
Houghton 2014 Abstract MiP20142014The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes.HumanLiver
Jaburek 2014 Abstract MiP20142014The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function.Islet cell;pancreas;thymus
Zorzano 2014 Abstract MiP20142014Metabolic implications of mitofusin 2 dysfunction.MouseSkeletal muscle
Kandashvili 2014 Abstract MiP20142014Regulation of energy metabolism in human colorectal cancer cells in situ.HumanEndothelial;epithelial;mesothelial cell
Kane 2014 Abstract MiP20142014Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect.RatSkeletal muscle
Kluckova 2014 Abstract MiP20142014Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13.Other cell lines
Komlodi 2014 Abstract MiP20142014Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation.Guinea pigNervous system
Kowaltowski 2014 Abstract MiP20142014Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation.Saccharomyces cerevisiae
Krumschnabel 2014 Abstract MiP20142014Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.MouseNervous system
Larsen 2014 Abstract MiP20142014The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.HumanSkeletal muscle
Fat
Wohlwend 2014 Abstract MiP20142014Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people.HumanSkeletal muscle
Felser 2014 Abstract MiP20142014Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry.HumanEndothelial;epithelial;mesothelial cell
HeLa
Fibroblast
Sobotka 2014 Abstract IOC952014Sobotka O (2014) Effect of α-Tocopheryl succinate on Complex II. Mitochondr Physiol Network 19.10RatHeart
Liver
... further results
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